hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06217
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ALS2 | Alsin (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein) (Amyotrophic lateral sclerosis 2 protein) | UniProt NCBI |
| NEK1 | Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (Never in mitosis A-related kinase 1) (NimA-related protein kinase 1) (Renal carcinoma antigen NY-REN-55) | UniProt NCBI |
| URM1 | Ubiquitin-related modifier 1 | UniProt NCBI |
| STXBP6 | Syntaxin-binding protein 6 (Amisyn) | UniProt NCBI |
| TEKT4 | Tektin-4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HPA:024020_23 | 0.0299775061854 | 0.8 | ALS2 STXBP6 NEK1 URM1 | kidney; cells in tubules[Approved,High] |
| HP:0007354 | 0.0417377803311 | 0.4 | ALS2 NEK1 | Amyotrophic lateral sclerosis |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ALS2 | STXBP6 | 0.549 | 0.643 | bioplex (STXBP6) bioplex_WMM |
| ALS2 | NEK1 | 0.138 | 0.406 | bioplex (ALS2) bioplex_WMM |
| NEK1 | TEKT4 | 0.096 | 0.359 | bioplex (TEKT4) bioplex_WMM |
| STXBP6 | URM1 | 0.038 | 0.261 | bioplex (STXBP6) bioplex_WMM |
| ALS2 | URM1 | 0.008 | 0.06 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_06217 has an average edge precision of 0.346 which is ranked 4050 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ALS2 | HuMAP2_00007 HuMAP2_03742 HuMAP2_06217 |
| NEK1 | HuMAP2_00805 HuMAP2_01908 HuMAP2_02878 HuMAP2_06049 HuMAP2_06217 |
| URM1 | HuMAP2_03742 HuMAP2_04244 HuMAP2_06217 |
| STXBP6 | HuMAP2_00007 HuMAP2_03742 HuMAP2_04244 HuMAP2_06217 |
| TEKT4 | HuMAP2_02639 HuMAP2_06049 HuMAP2_06178 HuMAP2_06217 HuMAP2_06686 |