hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06227
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RSL24D1 | Probable ribosome biogenesis protein RLP24 (Ribosomal L24 domain-containing protein 1) (Ribosomal protein L24-like) | UniProt NCBI |
| RPL37A | 60S ribosomal protein L37a (Large ribosomal subunit protein eL43) | UniProt NCBI |
| RPL37 | 60S ribosomal protein L37 (G1.16) (Large ribosomal subunit protein eL37) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:03010 | 1.07586932974e-05 | 1.0 | RPL37A RSL24D1 RPL37 | Ribosome |
| CORUM:5380 | 0.0010057650243 | 0.666666666667 | RPL37A RSL24D1 | TRBP containing complex (DICER, RPL7A, EIF6, MOV10 and subunits of the 60S ribosomal particle) |
| GO:0022625 | 0.00200709053011 | 1.0 | RPL37A RSL24D1 RPL37 | cytosolic large ribosomal subunit |
| CORUM:308 | 0.0034666239215 | 0.666666666667 | RPL37A RPL37 | 60S ribosomal subunit, cytoplasmic |
| WP:WP477 | 0.00357470816736 | 0.666666666667 | RPL37A RPL37 | Cytoplasmic Ribosomal Proteins |
| CORUM:306 | 0.0103042111837 | 0.666666666667 | RPL37A RPL37 | Ribosome, cytoplasmic |
| GO:0022626 | 0.0142448028307 | 1.0 | RPL37A RSL24D1 RPL37 | cytosolic ribosome |
| GO:0015934 | 0.0190659069388 | 1.0 | RPL37A RSL24D1 RPL37 | large ribosomal subunit |
| REAC:R-HSA-192823 | 0.0255313065434 | 0.666666666667 | RPL37A RPL37 | Viral mRNA Translation |
| REAC:R-HSA-156902 | 0.0255313065434 | 0.666666666667 | RPL37A RPL37 | Peptide chain elongation |
| REAC:R-HSA-156842 | 0.0279140119136 | 0.666666666667 | RPL37A RPL37 | Eukaryotic Translation Elongation |
| REAC:R-HSA-72764 | 0.0279140119136 | 0.666666666667 | RPL37A RPL37 | Eukaryotic Translation Termination |
| REAC:R-HSA-2408557 | 0.0279140119136 | 0.666666666667 | RPL37A RPL37 | Selenocysteine synthesis |
| REAC:R-HSA-975956 | 0.0291450496188 | 0.666666666667 | RPL37A RPL37 | Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) |
| REAC:R-HSA-72689 | 0.0329968164925 | 0.666666666667 | RPL37A RPL37 | Formation of a pool of free 40S subunits |
| REAC:R-HSA-156827 | 0.0399448421955 | 0.666666666667 | RPL37A RPL37 | L13a-mediated translational silencing of Ceruloplasmin expression |
| GO:0003735 | 0.0406485782564 | 1.0 | RPL37A RSL24D1 RPL37 | structural constituent of ribosome |
| REAC:R-HSA-1799339 | 0.0406759452204 | 0.666666666667 | RPL37A RPL37 | SRP-dependent cotranslational protein targeting to membrane |
| REAC:R-HSA-72706 | 0.0406759452204 | 0.666666666667 | RPL37A RPL37 | GTP hydrolysis and joining of the 60S ribosomal subunit |
| REAC:R-HSA-975957 | 0.0421579398286 | 0.666666666667 | RPL37A RPL37 | Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) |
| REAC:R-HSA-927802 | 0.0421579398286 | 0.666666666667 | RPL37A RPL37 | Nonsense-Mediated Decay (NMD) |
| REAC:R-HSA-2408522 | 0.0429088296136 | 0.666666666667 | RPL37A RPL37 | Selenoamino acid metabolism |
| REAC:R-HSA-72613 | 0.0459783176444 | 0.666666666667 | RPL37A RPL37 | Eukaryotic Translation Initiation |
| REAC:R-HSA-72737 | 0.0459783176444 | 0.666666666667 | RPL37A RPL37 | Cap-dependent Translation Initiation |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RPL37A | RPL37 | 0.941 | 0.853 | hein_WMM youn_WMM fraction treiber_WMM |
| RPL37A | RSL24D1 | 0.852 | 0.791 | bioplex (RPL37A) bioplex_WMM fraction treiber_WMM |
| RSL24D1 | RPL37 | 0.007 | 0.002 | WMM_only treiber_WMM |
Images
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Complex HuMAP2_06227 has an average edge precision of 0.549 which is ranked 2204 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| RSL24D1 | HuMAP2_01531 HuMAP2_06227 |
| RPL37A | HuMAP2_00484 HuMAP2_02207 HuMAP2_03749 HuMAP2_06227 |
| RPL37 | HuMAP2_03749 HuMAP2_06227 |