hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06228
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CSTF2T | Cleavage stimulation factor subunit 2 tau variant (CF-1 64 kDa subunit tau variant) (Cleavage stimulation factor 64 kDa subunit tau variant) (CSTF 64 kDa subunit tau variant) (TauCstF-64) | UniProt NCBI |
| CSTF2 | Cleavage stimulation factor subunit 2 (CF-1 64 kDa subunit) (Cleavage stimulation factor 64 kDa subunit) (CSTF 64 kDa subunit) (CstF-64) | UniProt NCBI |
| CSTF3 | Cleavage stimulation factor subunit 3 (CF-1 77 kDa subunit) (Cleavage stimulation factor 77 kDa subunit) (CSTF 77 kDa subunit) (CstF-77) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-77595 | 4.35659406764e-07 | 1.0 | CSTF3 CSTF2 CSTF2T | Processing of Intronless Pre-mRNAs |
| REAC:R-HSA-75067 | 1.47287948045e-06 | 1.0 | CSTF3 CSTF2 CSTF2T | Processing of Capped Intronless Pre-mRNA |
| KEGG:03015 | 3.30002227102e-06 | 1.0 | CSTF3 CSTF2 CSTF2T | mRNA surveillance pathway |
| CORUM:1146 | 1.00675659188e-05 | 0.666666666667 | CSTF2 CSTF3 | Cleavage stimulation factor |
| REAC:R-HSA-72187 | 1.11518017806e-05 | 1.0 | CSTF3 CSTF2 CSTF2T | mRNA 3'-end processing |
| REAC:R-HSA-73856 | 1.78539429329e-05 | 1.0 | CSTF3 CSTF2 CSTF2T | RNA Polymerase II Transcription Termination |
| WP:WP411 | 2.0466384774e-05 | 1.0 | CSTF3 CSTF2 CSTF2T | mRNA Processing |
| CORUM:2211 | 3.35555483123e-05 | 0.666666666667 | CSTF2 CSTF3 | BARD1-BRCA1-CSTF complex |
| CORUM:1147 | 7.04603414803e-05 | 0.666666666667 | CSTF2 CSTF3 | Polyadenylation complex (CSTF1, CSTF2, CSTF3, SYMPK CPSF1, CPSF2, CPSF3) |
| GO:0006379 | 7.41079580349e-05 | 1.0 | CSTF3 CSTF2 CSTF2T | mRNA cleavage |
| REAC:R-HSA-72163 | 0.000415506674825 | 1.0 | CSTF3 CSTF2 CSTF2T | mRNA Splicing - Major Pathway |
| REAC:R-HSA-72172 | 0.000474432644369 | 1.0 | CSTF3 CSTF2 CSTF2T | mRNA Splicing |
| GO:0006369 | 0.000594407580071 | 1.0 | CSTF3 CSTF2 CSTF2T | termination of RNA polymerase II transcription |
| REAC:R-HSA-72203 | 0.000960089475622 | 1.0 | CSTF3 CSTF2 CSTF2T | Processing of Capped Intron-Containing Pre-mRNA |
| GO:0090501 | 0.0015707980909 | 1.0 | CSTF3 CSTF2 CSTF2T | RNA phosphodiester bond hydrolysis |
| GO:0006353 | 0.00564855215433 | 1.0 | CSTF3 CSTF2 CSTF2T | DNA-templated transcription, termination |
| GO:0031124 | 0.0117851633362 | 1.0 | CSTF3 CSTF2 CSTF2T | mRNA 3'-end processing |
| REAC:R-HSA-8953854 | 0.0206735000409 | 1.0 | CSTF3 CSTF2 CSTF2T | Metabolism of RNA |
| GO:0090305 | 0.0310032822085 | 1.0 | CSTF3 CSTF2 CSTF2T | nucleic acid phosphodiester bond hydrolysis |
| GO:0031123 | 0.0356085105614 | 1.0 | CSTF3 CSTF2 CSTF2T | RNA 3'-end processing |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CSTF2 | CSTF3 | 0.996 | 0.927 | hein_WMM bioplex_WMM youn_WMM Malo fraction treiber_WMM |
| CSTF2 | CSTF2T | 0.987 | 0.901 | hein_WMM bioplex (CSTF2T) bioplex_WMM youn_WMM Malo gupta_WMM fraction |
| CSTF2T | CSTF3 | 0.617 | 0.674 | hein_WMM bioplex (CSTF2T) bioplex_WMM youn_WMM Malo gupta_WMM fraction |
Images
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Complex HuMAP2_06228 has an average edge precision of 0.834 which is ranked 826 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| CSTF2T | HuMAP2_02956 HuMAP2_06228 |
| CSTF2 | HuMAP2_01150 HuMAP2_02956 HuMAP2_06228 |
| CSTF3 | HuMAP2_02956 HuMAP2_06228 |