hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06248
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| INIP | SOSS complex subunit C (INTS3- and NABP-interacting protein) (Sensor of single-strand DNA complex subunit C) (Sensor of ssDNA subunit C) (SOSS-C) (Single-stranded DNA-binding protein-interacting protein 1) (SSB-interacting protein 1) (hSSBIP1) | UniProt NCBI |
| NABP2 | SOSS complex subunit B1 (Nucleic acid-binding protein 2) (Oligonucleotide/oligosaccharide-binding fold-containing protein 2B) (Sensor of single-strand DNA complex subunit B1) (Sensor of ssDNA subunit B1) (SOSS-B1) (Single-stranded DNA-binding protein 1) (hSSB1) | UniProt NCBI |
| INTS3 | Integrator complex subunit 3 (Int3) (SOSS complex subunit A) (Sensor of single-strand DNA complex subunit A) (SOSS-A) (Sensor of ssDNA subunit A) | UniProt NCBI |
| NABP1 | SOSS complex subunit B2 (Nucleic acid-binding protein 1) (Oligonucleotide/oligosaccharide-binding fold-containing protein 2A) (Sensor of single-strand DNA complex subunit B2) (Sensor of ssDNA subunit B2) (SOSS-B2) (Single-stranded DNA-binding protein 2) (hSSB2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0070876 | 2.4395561352e-11 | 1.0 | INTS3 NABP1 INIP NABP2 | SOSS complex |
| GO:0010212 | 5.18053162868e-05 | 1.0 | INTS3 NABP1 INIP NABP2 | response to ionizing radiation |
| REAC:R-HSA-6807505 | 8.72293047842e-05 | 0.75 | INTS3 NABP1 NABP2 | RNA polymerase II transcribes snRNA genes |
| GO:0009314 | 0.005282769645 | 1.0 | INTS3 NABP1 INIP NABP2 | response to radiation |
| GO:0042795 | 0.0198185309013 | 0.75 | INTS3 NABP1 NABP2 | snRNA transcription by RNA polymerase II |
| GO:0009301 | 0.0206918321066 | 0.75 | INTS3 NABP1 NABP2 | snRNA transcription |
| GO:0006281 | 0.042993565242 | 1.0 | INTS3 NABP1 INIP NABP2 | DNA repair |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| INIP | NABP2 | 0.994 | 0.923 | hein_WMM bioplex_WMM hein (NABP2) Malo fraction |
| NABP2 | INTS3 | 0.975 | 0.887 | hein_WMM bioplex_WMM hein (NABP2) Malo fraction |
| INIP | INTS3 | 0.717 | 0.73 | hein_WMM bioplex_WMM Malo fraction |
| INIP | NABP1 | 0.276 | 0.487 | hein_WMM hein (NABP1) |
| INTS3 | NABP1 | 0.055 | 0.311 | hein_WMM hein (NABP1) |
Images
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Complex HuMAP2_06248 has an average edge precision of 0.668 which is ranked 1533 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| INIP | HuMAP2_00768 HuMAP2_01055 HuMAP2_03907 HuMAP2_06248 |
| NABP2 | HuMAP2_00768 HuMAP2_01055 HuMAP2_03907 HuMAP2_06248 |
| INTS3 | HuMAP2_03907 HuMAP2_06248 |
| NABP1 | HuMAP2_06248 |