hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_06274
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| FGFR1 | Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331) | UniProt NCBI |
| FGFR2 | Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332) | UniProt NCBI |
| FGFR3 | Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0003795 | 5.93585464203e-09 | 1.0 | FGFR1 FGFR2 FGFR3 | Short middle phalanx of toe |
| HP:0002676 | 2.07754912471e-08 | 1.0 | FGFR1 FGFR2 FGFR3 | Cloverleaf skull |
| HP:0010183 | 4.98611789931e-08 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of the middle phalanges of the toes |
| HP:0004440 | 4.8436573879e-07 | 1.0 | FGFR1 FGFR2 FGFR3 | Coronal craniosynostosis |
| GO:0005007 | 9.08185760231e-07 | 1.0 | FGFR1 FGFR2 FGFR3 | fibroblast growth factor-activated receptor activity |
| HP:0008368 | 1.0512398571e-06 | 1.0 | FGFR1 FGFR2 FGFR3 | Tarsal synostosis |
| KEGG:05230 | 1.44061718026e-06 | 1.0 | FGFR1 FGFR2 FGFR3 | Central carbon metabolism in cancer |
| HP:0009138 | 1.54332220693e-06 | 1.0 | FGFR1 FGFR2 FGFR3 | Synostosis involving bones of the lower limbs |
| HP:0009140 | 1.54332220693e-06 | 1.0 | FGFR1 FGFR2 FGFR3 | Synostosis involving bones of the feet |
| HP:0000262 | 2.1689612862e-06 | 1.0 | FGFR1 FGFR2 FGFR3 | Turricephaly |
| WP:WP4155 | 2.43599896822e-06 | 1.0 | FGFR1 FGFR2 FGFR3 | Endometrial cancer |
| HP:0005819 | 3.88501686321e-06 | 1.0 | FGFR1 FGFR2 FGFR3 | Short middle phalanx of finger |
| WP:WP2064 | 4.52804673364e-06 | 1.0 | FGFR1 FGFR2 FGFR3 | Neural Crest Differentiation |
| HP:0010055 | 5.00748697602e-06 | 1.0 | FGFR1 FGFR2 FGFR3 | Broad hallux |
| HP:0010051 | 5.86462438633e-06 | 1.0 | FGFR1 FGFR2 FGFR3 | Deviation of the hallux |
| HP:0100266 | 6.32762104841e-06 | 1.0 | FGFR1 FGFR2 FGFR3 | Synostosis of carpals/tarsals |
| HP:0009843 | 6.32762104841e-06 | 1.0 | FGFR1 FGFR2 FGFR3 | Aplasia/Hypoplasia of the middle phalanges of the hand |
| WP:WP4540 | 6.82717373445e-06 | 1.0 | FGFR1 FGFR2 FGFR3 | Pathways Regulating Hippo Signaling |
| HP:0009833 | 7.32543821373e-06 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormal middle phalanx morphology of the hand |
| HP:0008122 | 8.83967473292e-06 | 0.666666666667 | FGFR1 FGFR2 | Calcaneonavicular fusion |
| HP:0005347 | 8.83967473292e-06 | 0.666666666667 | FGFR1 FGFR2 | Cartilaginous trachea |
| HP:0000614 | 9.01062734661e-06 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormal nasolacrimal system morphology |
| KEGG:04550 | 9.10053254791e-06 | 1.0 | FGFR1 FGFR2 FGFR3 | Signaling pathways regulating pluripotency of stem cells |
| HP:0001837 | 9.62498830206e-06 | 1.0 | FGFR1 FGFR2 FGFR3 | Broad toe |
| WP:WP3931 | 9.79655470838e-06 | 1.0 | FGFR1 FGFR2 FGFR3 | ESC Pluripotency Pathways |
| HP:0100257 | 1.02666541889e-05 | 1.0 | FGFR1 FGFR2 FGFR3 | Ectrodactyly |
| REAC:R-HSA-1226099 | 1.05322572372e-05 | 1.0 | FGFR1 FGFR2 FGFR3 | Signaling by FGFR in disease |
| WP:WP4541 | 1.10592549668e-05 | 1.0 | FGFR1 FGFR2 FGFR3 | Hippo-Merlin Signaling Dysregulation |
| HP:0002308 | 1.2361417292e-05 | 1.0 | FGFR1 FGFR2 FGFR3 | Arnold-Chiari malformation |
| HP:0000676 | 1.2361417292e-05 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of the incisor |
| HP:0011304 | 1.92968698558e-05 | 1.0 | FGFR1 FGFR2 FGFR3 | Broad thumb |
| WP:WP51 | 2.41319770871e-05 | 1.0 | FGFR1 FGFR2 FGFR3 | Regulation of Actin Cytoskeleton |
| KEGG:04015 | 2.55027583186e-05 | 1.0 | FGFR1 FGFR2 FGFR3 | Rap1 signaling pathway |
| HP:0009740 | 2.65178370278e-05 | 0.666666666667 | FGFR2 FGFR3 | Aplasia of the parotid gland |
| HP:0007656 | 2.65178370278e-05 | 0.666666666667 | FGFR2 FGFR3 | Lacrimal gland aplasia |
| HP:0009637 | 2.65178370278e-05 | 0.666666666667 | FGFR2 FGFR3 | Absent proximal phalanx of thumb |
| HP:0009462 | 2.65178370278e-05 | 0.666666666667 | FGFR2 FGFR3 | Radial deviation of the 3rd finger |
| HP:0009899 | 2.65178370278e-05 | 0.666666666667 | FGFR2 FGFR3 | Prominent crus of helix |
| HP:0007892 | 2.65178370278e-05 | 0.666666666667 | FGFR2 FGFR3 | Hypoplasia of the lacrimal punctum |
| HP:0100583 | 2.65178370278e-05 | 0.666666666667 | FGFR2 FGFR3 | Corneal perforation |
| HP:0032107 | 2.65178370278e-05 | 0.666666666667 | FGFR2 FGFR3 | Limbal stem cell deficiency |
| HP:0005707 | 2.65178370278e-05 | 0.666666666667 | FGFR2 FGFR3 | Bilateral triphalangeal thumbs |
| HP:0009741 | 2.65178370278e-05 | 0.666666666667 | FGFR2 FGFR3 | Nephrosclerosis |
| KEGG:04014 | 3.07154438585e-05 | 1.0 | FGFR1 FGFR2 FGFR3 | Ras signaling pathway |
| HP:0000678 | 3.11003168115e-05 | 1.0 | FGFR1 FGFR2 FGFR3 | Dental crowding |
| KEGG:04810 | 3.2250969458e-05 | 1.0 | FGFR1 FGFR2 FGFR3 | Regulation of actin cytoskeleton |
| HP:0009768 | 3.24928683105e-05 | 1.0 | FGFR1 FGFR2 FGFR3 | Broad phalanges of the hand |
| HP:0001831 | 3.39263772065e-05 | 1.0 | FGFR1 FGFR2 FGFR3 | Short toe |
| WP:WP4223 | 3.92056063451e-05 | 1.0 | FGFR1 FGFR2 FGFR3 | Ras Signaling |
| HP:0001850 | 4.00818584703e-05 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of the tarsal bones |
| HP:0006501 | 4.17290581335e-05 | 1.0 | FGFR1 FGFR2 FGFR3 | Aplasia/Hypoplasia of the radius |
| HP:0000601 | 4.34207767065e-05 | 1.0 | FGFR1 FGFR2 FGFR3 | Hypotelorism |
| HP:0100538 | 4.34207767065e-05 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of the supraorbital ridges |
| HP:0007732 | 5.30332997138e-05 | 0.666666666667 | FGFR2 FGFR3 | Lacrimal gland hypoplasia |
| HP:0000198 | 5.30332997138e-05 | 0.666666666667 | FGFR2 FGFR3 | Absence of Stensen duct |
| HP:0007900 | 5.30332997138e-05 | 0.666666666667 | FGFR2 FGFR3 | Hypoplastic lacrimal duct |
| HP:0005037 | 5.30332997138e-05 | 0.666666666667 | FGFR2 FGFR3 | Proximal radio-ulnar synostosis |
| HP:0008080 | 5.30332997138e-05 | 0.666666666667 | FGFR1 FGFR2 | Hallux varus |
| HP:0009629 | 5.30332997138e-05 | 0.666666666667 | FGFR2 FGFR3 | Aplasia/Hypoplasia of the proximal phalanx of the thumb |
| HP:0009317 | 5.30332997138e-05 | 0.666666666667 | FGFR2 FGFR3 | Deviation of the 3rd finger |
| HP:0011318 | 5.30332997138e-05 | 0.666666666667 | FGFR1 FGFR2 | Bicoronal synostosis |
| HP:0008743 | 5.30332997138e-05 | 0.666666666667 | FGFR2 FGFR3 | Coronal hypospadias |
| HP:0004279 | 5.86284362994e-05 | 1.0 | FGFR1 FGFR2 FGFR3 | Short palm |
| HP:0100498 | 6.07475364066e-05 | 1.0 | FGFR1 FGFR2 FGFR3 | Deviation of toes |
| HP:0001500 | 6.29170912782e-05 | 1.0 | FGFR1 FGFR2 FGFR3 | Broad finger |
| HP:0006503 | 6.74099396568e-05 | 1.0 | FGFR1 FGFR2 FGFR3 | Aplasia/hypoplasia involving forearm bones |
| HP:0009601 | 6.97344203346e-05 | 1.0 | FGFR1 FGFR2 FGFR3 | Aplasia/Hypoplasia of the thumb |
| HP:0100238 | 7.21117301188e-05 | 1.0 | FGFR1 FGFR2 FGFR3 | Synostosis involving bones of the upper limbs |
| GO:0017134 | 7.41079580349e-05 | 1.0 | FGFR1 FGFR2 FGFR3 | fibroblast growth factor binding |
| HP:0006009 | 7.70272113478e-05 | 1.0 | FGFR1 FGFR2 FGFR3 | Broad phalanx |
| HP:0000453 | 7.70272113478e-05 | 1.0 | FGFR1 FGFR2 FGFR3 | Choanal atresia |
| HP:0000889 | 8.21611320277e-05 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of the clavicle |
| KEGG:04010 | 8.31056129839e-05 | 1.0 | FGFR1 FGFR2 FGFR3 | MAPK signaling pathway |
| HP:0001991 | 8.48114911254e-05 | 1.0 | FGFR1 FGFR2 FGFR3 | Aplasia/Hypoplasia of toe |
| HP:0001773 | 8.75182408421e-05 | 1.0 | FGFR1 FGFR2 FGFR3 | Short foot |
| HP:0001092 | 8.83848756199e-05 | 0.666666666667 | FGFR2 FGFR3 | Absent lacrimal punctum |
| HP:0008038 | 8.83848756199e-05 | 0.666666666667 | FGFR2 FGFR3 | Aplastic/hypoplastic lacrimal glands |
| HP:0011479 | 8.83848756199e-05 | 0.666666666667 | FGFR2 FGFR3 | Abnormal lacrimal punctum morphology |
| HP:0000415 | 9.02819747635e-05 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of the choanae |
| HP:0000327 | 9.31032864748e-05 | 1.0 | FGFR1 FGFR2 FGFR3 | Hypoplasia of the maxilla |
| HP:0010161 | 9.59827695617e-05 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of the phalanges of the toes |
| HP:0003764 | 9.59827695617e-05 | 1.0 | FGFR1 FGFR2 FGFR3 | Nevus |
| HP:0005622 | 9.59827695617e-05 | 1.0 | FGFR1 FGFR2 FGFR3 | Broad long bones |
| WP:WP382 | 0.000111215333222 | 1.0 | FGFR1 FGFR2 FGFR3 | MAPK Signaling Pathway |
| HP:0001844 | 0.00012118403403 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of the hallux |
| HP:0000326 | 0.000131666159742 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of the maxilla |
| HP:0000620 | 0.000132571377575 | 0.666666666667 | FGFR2 FGFR3 | Dacryocystitis |
| HP:0009895 | 0.000132571377575 | 0.666666666667 | FGFR2 FGFR3 | Abnormality of the crus of the helix |
| HP:0001245 | 0.000132571377575 | 0.666666666667 | FGFR2 FGFR3 | Small thenar eminence |
| HP:0001227 | 0.000132571377575 | 0.666666666667 | FGFR2 FGFR3 | Abnormality of the thenar eminence |
| HP:0009618 | 0.000132571377575 | 0.666666666667 | FGFR2 FGFR3 | Abnormality of the proximal phalanx of the thumb |
| HP:0010239 | 0.000132571377575 | 0.666666666667 | FGFR2 FGFR3 | Aplasia of the middle phalanx of the hand |
| HP:0011482 | 0.000132571377575 | 0.666666666667 | FGFR2 FGFR3 | Abnormal lacrimal gland morphology |
| KEGG:04151 | 0.00013397544306 | 1.0 | FGFR1 FGFR2 FGFR3 | PI3K-Akt signaling pathway |
| HP:0000506 | 0.000138979726247 | 1.0 | FGFR1 FGFR2 FGFR3 | Telecanthus |
| HP:0000104 | 0.000154409386803 | 1.0 | FGFR1 FGFR2 FGFR3 | Renal agenesis |
| HP:0001363 | 0.000170940741981 | 1.0 | FGFR1 FGFR2 FGFR3 | Craniosynostosis |
| WP:WP3932 | 0.000177999256178 | 1.0 | FGFR1 FGFR2 FGFR3 | Focal Adhesion-PI3K-Akt-mTOR-signaling pathway |
| HP:0004150 | 0.000185591618409 | 0.666666666667 | FGFR2 FGFR3 | Abnormal 3rd finger morphology |
| HP:0009659 | 0.000185591618409 | 0.666666666667 | FGFR2 FGFR3 | Partial absence of thumb |
| HP:0006110 | 0.000185591618409 | 0.666666666667 | FGFR1 FGFR2 | Shortening of all middle phalanges of the fingers |
| HP:0003070 | 0.000185591618409 | 0.666666666667 | FGFR1 FGFR2 | Elbow ankylosis |
| HP:0000244 | 0.000185591618409 | 0.666666666667 | FGFR1 FGFR2 | Brachyturricephaly |
| HP:0009602 | 0.000197886554129 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of thumb phalanx |
| HP:0006711 | 0.000212361135673 | 1.0 | FGFR1 FGFR2 FGFR3 | Aplasia/Hypoplasia involving bones of the thorax |
| HP:0009774 | 0.000212361135673 | 1.0 | FGFR1 FGFR2 FGFR3 | Triangular shaped phalanges of the hand |
| HP:0000197 | 0.00024744441095 | 0.666666666667 | FGFR2 FGFR3 | Abnormal parotid gland morphology |
| HP:3000022 | 0.00024744441095 | 0.666666666667 | FGFR2 FGFR3 | Abnormality of cartilage of external ear |
| WP:WP4172 | 0.000251129143237 | 1.0 | FGFR1 FGFR2 FGFR3 | PI3K-Akt Signaling Pathway |
| HP:0001428 | 0.000277311257167 | 1.0 | FGFR1 FGFR2 FGFR3 | Somatic mutation |
| HP:0100240 | 0.000283253641249 | 1.0 | FGFR1 FGFR2 FGFR3 | Synostosis of joints |
| HP:0001233 | 0.000318128568027 | 0.666666666667 | FGFR2 FGFR3 | 2-3 finger syndactyly |
| HP:0001783 | 0.000318128568027 | 0.666666666667 | FGFR1 FGFR2 | Broad metatarsal |
| HP:0000248 | 0.00034059933936 | 1.0 | FGFR1 FGFR2 FGFR3 | Brachycephaly |
| HP:0003026 | 0.000347411326147 | 1.0 | FGFR1 FGFR2 FGFR3 | Short long bone |
| HP:0002781 | 0.00039764290247 | 0.666666666667 | FGFR2 FGFR3 | Upper airway obstruction |
| HP:0003938 | 0.00039764290247 | 0.666666666667 | FGFR1 FGFR2 | Synostosis involving the elbow |
| HP:0003041 | 0.00039764290247 | 0.666666666667 | FGFR1 FGFR2 | Humeroradial synostosis |
| HP:0002818 | 0.000397654774179 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of the radius |
| HP:0000606 | 0.000397654774179 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of the periorbital region |
| HP:0006101 | 0.000412850562063 | 1.0 | FGFR1 FGFR2 FGFR3 | Finger syndactyly |
| HP:0009803 | 0.000452522846563 | 1.0 | FGFR1 FGFR2 FGFR3 | Short phalanx of finger |
| HP:0000272 | 0.000477503890824 | 1.0 | FGFR1 FGFR2 FGFR3 | Malar flattening |
| HP:0410007 | 0.000485986227107 | 0.666666666667 | FGFR2 FGFR3 | Abnormality of cartilage morphology |
| HP:0009802 | 0.000485986227107 | 0.666666666667 | FGFR2 FGFR3 | Aplasia of the phalanges of the hand |
| HP:0009823 | 0.000485986227107 | 0.666666666667 | FGFR2 FGFR3 | Aplasia involving bones of the upper limbs |
| HP:0040072 | 0.000486030746017 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of forearm bone |
| KEGG:05200 | 0.000500689425538 | 1.0 | FGFR1 FGFR2 FGFR3 | Pathways in cancer |
| HP:0006482 | 0.000503387778576 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of dental morphology |
| HP:0002973 | 0.000503387778576 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of the forearm |
| HP:0006292 | 0.000512219143112 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of dental eruption |
| HP:0012369 | 0.000548577439966 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of malar bones |
| HP:0000520 | 0.000567384601813 | 1.0 | FGFR1 FGFR2 FGFR3 | Proptosis |
| HP:0011386 | 0.000583157354768 | 0.666666666667 | FGFR2 FGFR3 | Narrow internal auditory canal |
| HP:0000680 | 0.000583157354768 | 0.666666666667 | FGFR2 FGFR3 | Delayed eruption of primary teeth |
| HP:0009944 | 0.000583157354768 | 0.666666666667 | FGFR2 FGFR3 | Partial duplication of thumb phalanx |
| HP:0000522 | 0.000583157354768 | 0.666666666667 | FGFR2 FGFR3 | Alacrima |
| HP:0000348 | 0.00060627869577 | 1.0 | FGFR1 FGFR2 FGFR3 | High forehead |
| HP:0009811 | 0.000636587763158 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of the elbow |
| HP:0009826 | 0.000657344853255 | 1.0 | FGFR1 FGFR2 FGFR3 | Limb undergrowth |
| HP:0009767 | 0.000657344853255 | 1.0 | FGFR1 FGFR2 FGFR3 | Aplasia/Hypoplasia of the phalanges of the hand |
| HP:0006487 | 0.000678548319622 | 1.0 | FGFR1 FGFR2 FGFR3 | Bowing of the long bones |
| HP:0009999 | 0.000689155098282 | 0.666666666667 | FGFR2 FGFR3 | Partial duplication of the phalanx of hand |
| HP:0000495 | 0.000689155098282 | 0.666666666667 | FGFR2 FGFR3 | Recurrent corneal erosions |
| HP:0006504 | 0.000722313375898 | 1.0 | FGFR1 FGFR2 FGFR3 | Anomaly of the limb diaphyses |
| HP:0010668 | 0.000722313375898 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of the zygomatic bone |
| HP:0006494 | 0.000733541044953 | 1.0 | FGFR1 FGFR2 FGFR3 | Aplasia/Hypoplasia involving bones of the feet |
| HP:0009825 | 0.000803978270478 | 0.666666666667 | FGFR2 FGFR3 | Aplasia involving bones of the extremities |
| HP:0010286 | 0.000803978270478 | 0.666666666667 | FGFR2 FGFR3 | Abnormal salivary gland morphology |
| HP:0000452 | 0.000803978270478 | 0.666666666667 | FGFR1 FGFR2 | Choanal stenosis |
| HP:0011800 | 0.000890249981845 | 1.0 | FGFR1 FGFR2 FGFR3 | Midface retrusion |
| HP:0100761 | 0.000927625684184 | 0.666666666667 | FGFR1 FGFR2 | Visceral angiomatosis |
| HP:3000030 | 0.000927625684184 | 0.666666666667 | FGFR1 FGFR2 | Abnormality of bony orbit of skull |
| HP:0000410 | 0.000927625684184 | 0.666666666667 | FGFR2 FGFR3 | Mixed hearing impairment |
| HP:0011384 | 0.000927625684184 | 0.666666666667 | FGFR2 FGFR3 | Abnormality of the internal auditory canal |
| HP:0002780 | 0.000927625684184 | 0.666666666667 | FGFR1 FGFR2 | Bronchomalacia |
| HP:0000586 | 0.000927625684184 | 0.666666666667 | FGFR1 FGFR2 | Shallow orbits |
| HP:0000940 | 0.000969535785884 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormal diaphysis morphology |
| HP:0009381 | 0.000983191219488 | 1.0 | FGFR1 FGFR2 FGFR3 | Short finger |
| HP:0009804 | 0.000996974273967 | 1.0 | FGFR1 FGFR2 FGFR3 | Reduced number of teeth |
| HP:0008678 | 0.00105339457234 | 1.0 | FGFR1 FGFR2 FGFR3 | Renal hypoplasia/aplasia |
| HP:0100702 | 0.00106009615223 | 0.666666666667 | FGFR1 FGFR2 | Arachnoid cyst |
| HP:0000633 | 0.00106009615223 | 0.666666666667 | FGFR2 FGFR3 | Decreased lacrimation |
| HP:0010059 | 0.00106009615223 | 0.666666666667 | FGFR1 FGFR2 | Broad hallux phalanx |
| HP:0100700 | 0.00106009615223 | 0.666666666667 | FGFR1 FGFR2 | Abnormal arachnoid mater morphology |
| HP:0012385 | 0.00106782463497 | 1.0 | FGFR1 FGFR2 FGFR3 | Camptodactyly |
| HP:0000692 | 0.00108238588 | 1.0 | FGFR1 FGFR2 FGFR3 | Misalignment of teeth |
| GO:0010518 | 0.0011207920467 | 1.0 | FGFR1 FGFR2 FGFR3 | positive regulation of phospholipase activity |
| HP:0011329 | 0.00115718061641 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of cranial sutures |
| HP:0002410 | 0.00120138848745 | 0.666666666667 | FGFR1 FGFR2 | Aqueductal stenosis |
| HP:0007461 | 0.00120138848745 | 0.666666666667 | FGFR1 FGFR2 | Hemangiomatosis |
| KEGG:01521 | 0.00120571114426 | 0.666666666667 | FGFR2 FGFR3 | EGFR tyrosine kinase inhibitor resistance |
| WP:WP474 | 0.00122029571265 | 0.666666666667 | FGFR1 FGFR3 | Endochondral Ossification |
| HP:0030044 | 0.00131695007996 | 1.0 | FGFR1 FGFR2 FGFR3 | Flexion contracture of digit |
| HP:0006483 | 0.00133369097081 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormal number of teeth |
| HP:0011065 | 0.00135150150266 | 0.666666666667 | FGFR2 FGFR3 | Conical incisor |
| HP:0031013 | 0.00135150150266 | 0.666666666667 | FGFR1 FGFR2 | Ankylosis |
| HP:0000047 | 0.00138476365773 | 1.0 | FGFR1 FGFR2 FGFR3 | Hypospadias |
| HP:0000579 | 0.0015104340107 | 0.666666666667 | FGFR2 FGFR3 | Nasolacrimal duct obstruction |
| HP:0003312 | 0.0015272953994 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormal form of the vertebral bodies |
| HP:0006265 | 0.00154577074697 | 1.0 | FGFR1 FGFR2 FGFR3 | Aplasia/Hypoplasia of fingers |
| HP:0032076 | 0.00162116203678 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormal male urethral meatus morphology |
| HP:0100627 | 0.00162116203678 | 1.0 | FGFR1 FGFR2 FGFR3 | Displacement of the urethral meatus |
| HP:0006493 | 0.00164038530204 | 1.0 | FGFR1 FGFR2 FGFR3 | Aplasia/hypoplasia involving bones of the lower limbs |
| HP:0000882 | 0.0016781848244 | 0.666666666667 | FGFR1 FGFR3 | Hypoplastic scapulae |
| HP:0002438 | 0.00167928651902 | 1.0 | FGFR1 FGFR2 FGFR3 | Cerebellar malformation |
| HP:0007360 | 0.00169896565791 | 1.0 | FGFR1 FGFR2 FGFR3 | Aplasia/Hypoplasia of the cerebellum |
| HP:0001172 | 0.00171879794186 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormal thumb morphology |
| HP:0001156 | 0.00171879794186 | 1.0 | FGFR1 FGFR2 FGFR3 | Brachydactyly |
| KEGG:05215 | 0.00178652468712 | 0.666666666667 | FGFR1 FGFR2 | Prostate cancer |
| GO:0010517 | 0.00189129684568 | 1.0 | FGFR1 FGFR2 FGFR3 | regulation of phospholipase activity |
| GO:0060193 | 0.00189129684568 | 1.0 | FGFR1 FGFR2 FGFR3 | positive regulation of lipase activity |
| HP:0001631 | 0.0019042779662 | 1.0 | FGFR1 FGFR2 FGFR3 | Atrial septal defect |
| HP:0100871 | 0.00192567434784 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of the palm |
| HP:0011994 | 0.00192567434784 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormal atrial septum morphology |
| HP:0002032 | 0.00204013662007 | 0.666666666667 | FGFR1 FGFR2 | Esophageal atresia |
| HP:0001355 | 0.00204013662007 | 0.666666666667 | FGFR2 FGFR3 | Megalencephaly |
| HP:0006713 | 0.00204013662007 | 0.666666666667 | FGFR1 FGFR3 | Aplasia/Hypoplasia of the scapulae |
| HP:0003319 | 0.00212549836492 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of the cervical spine |
| HP:0005120 | 0.00212549836492 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormal cardiac atrium morphology |
| HP:0001376 | 0.00217170365104 | 1.0 | FGFR1 FGFR2 FGFR3 | Limitation of joint mobility |
| HP:0005922 | 0.00219505530321 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormal hand morphology |
| HP:0011218 | 0.00219505530321 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormal shape of the frontal region |
| HP:0002007 | 0.00219505530321 | 1.0 | FGFR1 FGFR2 FGFR3 | Frontal bossing |
| HP:0009738 | 0.00223433522771 | 0.666666666667 | FGFR2 FGFR3 | Abnormality of the antihelix |
| HP:0000238 | 0.00229013582286 | 1.0 | FGFR1 FGFR2 FGFR3 | Hydrocephalus |
| WP:WP4657 | 0.00230941333173 | 0.666666666667 | FGFR1 FGFR2 | 22q11.2 Deletion Syndrome |
| HP:0003974 | 0.00243734739233 | 0.666666666667 | FGFR2 FGFR3 | Absent radius |
| HP:0002360 | 0.00246306270181 | 1.0 | FGFR1 FGFR2 FGFR3 | Sleep disturbance |
| GO:0004714 | 0.00251749092736 | 1.0 | FGFR1 FGFR2 FGFR3 | transmembrane receptor protein tyrosine kinase activity |
| HP:0000795 | 0.00259176983801 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of the urethra |
| HP:0001159 | 0.00261803777556 | 1.0 | FGFR1 FGFR2 FGFR3 | Syndactyly |
| HP:0009822 | 0.00264917192674 | 0.666666666667 | FGFR2 FGFR3 | Aplasia involving forearm bones |
| HP:0010109 | 0.00264917192674 | 0.666666666667 | FGFR1 FGFR2 | Short hallux |
| HP:0003953 | 0.00264917192674 | 0.666666666667 | FGFR2 FGFR3 | Absent forearm bone |
| HP:0001377 | 0.00264917192674 | 0.666666666667 | FGFR2 FGFR3 | Limited elbow extension |
| HP:0000235 | 0.00269790529335 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of the fontanelles or cranial sutures |
| REAC:R-HSA-5663202 | 0.00284240562301 | 1.0 | FGFR1 FGFR2 FGFR3 | Diseases of signal transduction |
| HP:0009942 | 0.00286980764378 | 0.666666666667 | FGFR2 FGFR3 | Duplication of thumb phalanx |
| HP:0011481 | 0.00286980764378 | 0.666666666667 | FGFR2 FGFR3 | Abnormal lacrimal duct morphology |
| HP:0000243 | 0.00309925335629 | 0.666666666667 | FGFR1 FGFR2 | Trigonocephaly |
| HP:0008362 | 0.00309925335629 | 0.666666666667 | FGFR1 FGFR2 | Aplasia/Hypoplasia of the hallux |
| HP:0000256 | 0.00315141408537 | 1.0 | FGFR1 FGFR2 FGFR3 | Macrocephaly |
| HP:0040194 | 0.00315141408537 | 1.0 | FGFR1 FGFR2 FGFR3 | Increased head circumference |
| WP:WP2261 | 0.00317409068183 | 0.666666666667 | FGFR1 FGFR2 | Signaling Pathways in Glioblastoma |
| HP:0011368 | 0.00321143982185 | 1.0 | FGFR1 FGFR2 FGFR3 | Epidermal thickening |
| HP:0002761 | 0.00333750787708 | 0.666666666667 | FGFR1 FGFR3 | Generalized joint laxity |
| HP:0040070 | 0.00342752570631 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormal upper limb bone morphology |
| HP:0003468 | 0.00355524749065 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormal vertebral morphology |
| HP:0009658 | 0.00358457001899 | 0.666666666667 | FGFR2 FGFR3 | Aplasia/Hypoplasia of the phalanges of the thumb |
| HP:0011063 | 0.00358457001899 | 0.666666666667 | FGFR2 FGFR3 | Abnormality of incisor morphology |
| HP:0000698 | 0.00358457001899 | 0.666666666667 | FGFR2 FGFR3 | Conical tooth |
| HP:0000643 | 0.00358457001899 | 0.666666666667 | FGFR2 FGFR3 | Blepharospasm |
| HP:0001000 | 0.00365309352498 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of skin pigmentation |
| HP:0007392 | 0.00384043859485 | 0.666666666667 | FGFR2 FGFR3 | Excessive wrinkled skin |
| HP:0009702 | 0.00410511241748 | 0.666666666667 | FGFR2 FGFR3 | Carpal synostosis |
| HP:0000494 | 0.00420537493824 | 1.0 | FGFR1 FGFR2 FGFR3 | Downslanted palpebral fissures |
| HP:0030084 | 0.00427808915761 | 1.0 | FGFR1 FGFR2 FGFR3 | Clinodactyly |
| HP:0001072 | 0.00435163677096 | 1.0 | FGFR1 FGFR2 FGFR3 | Thickened skin |
| HP:0100728 | 0.00437859029972 | 0.666666666667 | FGFR2 FGFR3 | Germ cell neoplasia |
| HP:0010174 | 0.00437859029972 | 0.666666666667 | FGFR1 FGFR2 | Broad phalanx of the toes |
| HP:0031879 | 0.00437859029972 | 0.666666666667 | FGFR2 FGFR3 | Abnormal eyelid physiology |
| HP:0100744 | 0.00437859029972 | 0.666666666667 | FGFR1 FGFR2 | Abnormality of the humeroradial joint |
| HP:0032040 | 0.00437859029972 | 0.666666666667 | FGFR2 FGFR3 | Abnormal ocular adnexa physiology |
| HP:0005280 | 0.00453918306631 | 1.0 | FGFR1 FGFR2 FGFR3 | Depressed nasal bridge |
| HP:0005927 | 0.00457732746182 | 1.0 | FGFR1 FGFR2 FGFR3 | Aplasia/hypoplasia involving bones of the hand |
| HP:0010057 | 0.00466087105439 | 0.666666666667 | FGFR1 FGFR2 | Abnormality of the phalanges of the hallux |
| HP:0002980 | 0.00495195349433 | 0.666666666667 | FGFR2 FGFR3 | Femoral bowing |
| HP:0000378 | 0.00495195349433 | 0.666666666667 | FGFR2 FGFR3 | Cupped ear |
| HP:0000956 | 0.00495195349433 | 0.666666666667 | FGFR2 FGFR3 | Acanthosis nigricans |
| GO:0060191 | 0.00497140885151 | 1.0 | FGFR1 FGFR2 FGFR3 | regulation of lipase activity |
| HP:0000286 | 0.00505185155361 | 1.0 | FGFR1 FGFR2 FGFR3 | Epicanthus |
| HP:0009810 | 0.00509281251216 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of upper limb joint |
| GO:0019199 | 0.0051907357126 | 1.0 | FGFR1 FGFR2 FGFR3 | transmembrane receptor protein kinase activity |
| HP:0002984 | 0.00556051868131 | 0.666666666667 | FGFR2 FGFR3 | Hypoplasia of the radius |
| HP:0030962 | 0.00568972146137 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormal morphology of the great vessels |
| HP:0002921 | 0.00586844410879 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of the cerebrospinal fluid |
| HP:0006496 | 0.00586844410879 | 1.0 | FGFR1 FGFR2 FGFR3 | Aplasia/hypoplasia involving bones of the upper limbs |
| HP:0004278 | 0.00587799905401 | 0.666666666667 | FGFR2 FGFR3 | Synostosis involving bones of the hand |
| HP:0001822 | 0.00587799905401 | 0.666666666667 | FGFR2 FGFR3 | Hallux valgus |
| HP:0002692 | 0.00587799905401 | 0.666666666667 | FGFR1 FGFR2 | Hypoplastic facial bones |
| HP:0010807 | 0.00587799905401 | 0.666666666667 | FGFR2 FGFR3 | Open bite |
| HP:0200020 | 0.00620427636329 | 0.666666666667 | FGFR2 FGFR3 | Corneal erosion |
| HP:0010743 | 0.00620427636329 | 0.666666666667 | FGFR1 FGFR2 | Short metatarsal |
| HP:0011927 | 0.00633153871247 | 1.0 | FGFR1 FGFR2 FGFR3 | Short digit |
| HP:0002991 | 0.00653934942198 | 0.666666666667 | FGFR2 FGFR3 | Abnormality of fibula morphology |
| HP:0009380 | 0.0068832170429 | 0.666666666667 | FGFR2 FGFR3 | Aplasia of the fingers |
| HP:0003063 | 0.0068832170429 | 0.666666666667 | FGFR1 FGFR2 | Abnormality of the humerus |
| GO:0008543 | 0.00690911398953 | 1.0 | FGFR1 FGFR2 FGFR3 | fibroblast growth factor receptor signaling pathway |
| HP:0000309 | 0.00707088502327 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of the midface |
| HP:0100678 | 0.0072358780389 | 0.666666666667 | FGFR2 FGFR3 | Premature skin wrinkling |
| HP:0001964 | 0.00759733122278 | 0.666666666667 | FGFR1 FGFR2 | Aplasia/Hypoplasia of metatarsal bones |
| HP:0006481 | 0.00759733122278 | 0.666666666667 | FGFR2 FGFR3 | Abnormality of primary teeth |
| HP:0000008 | 0.00764818547026 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of female internal genitalia |
| HP:0002093 | 0.00781090802149 | 1.0 | FGFR1 FGFR2 FGFR3 | Respiratory insufficiency |
| HP:0000175 | 0.00781090802149 | 1.0 | FGFR1 FGFR2 FGFR3 | Cleft palate |
| HP:0100737 | 0.00786565737678 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormal hard palate morphology |
| GO:0048705 | 0.00804289309261 | 1.0 | FGFR1 FGFR2 FGFR3 | skeletal system morphogenesis |
| HP:0000463 | 0.00831289078327 | 1.0 | FGFR1 FGFR2 FGFR3 | Anteverted nares |
| HP:0000974 | 0.00834660940556 | 0.666666666667 | FGFR2 FGFR3 | Hyperextensible skin |
| HP:0001199 | 0.00834660940556 | 0.666666666667 | FGFR2 FGFR3 | Triphalangeal thumb |
| HP:0009891 | 0.00834660940556 | 0.666666666667 | FGFR2 FGFR3 | Underdeveloped supraorbital ridges |
| HP:0001671 | 0.00895506774716 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormal cardiac septum morphology |
| HP:0005288 | 0.00901503471868 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of the nares |
| HP:0001171 | 0.00913104209388 | 0.666666666667 | FGFR1 FGFR3 | Split hand |
| HP:0100491 | 0.00938046670593 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of lower limb joint |
| HP:0000812 | 0.00950443643655 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormal internal genitalia |
| HP:0000995 | 0.00953643840968 | 0.666666666667 | FGFR2 FGFR3 | Melanocytic nevus |
| HP:0045060 | 0.00956682879828 | 1.0 | FGFR1 FGFR2 FGFR3 | Aplasia/hypoplasia involving bones of the extremities |
| HP:0000218 | 0.00975564299217 | 1.0 | FGFR1 FGFR2 FGFR3 | High palate |
| HP:0000202 | 0.00988288931455 | 1.0 | FGFR1 FGFR2 FGFR3 | Oral cleft |
| HP:0000217 | 0.00995061979035 | 0.666666666667 | FGFR2 FGFR3 | Xerostomia |
| HP:0000629 | 0.0103735850487 | 0.666666666667 | FGFR2 FGFR3 | Periorbital fullness |
| HP:0040071 | 0.0108053329976 | 0.666666666667 | FGFR2 FGFR3 | Abnormal morphology of ulna |
| HP:0003022 | 0.0108053329976 | 0.666666666667 | FGFR2 FGFR3 | Hypoplasia of the ulna |
| HP:0001454 | 0.0108053329976 | 0.666666666667 | FGFR1 FGFR2 | Abnormality of the upper arm |
| HP:0010460 | 0.0110094432953 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of the female genitalia |
| HP:0002119 | 0.0110094432953 | 1.0 | FGFR1 FGFR2 FGFR3 | Ventriculomegaly |
| GO:0044344 | 0.0110330947082 | 1.0 | FGFR1 FGFR2 FGFR3 | cellular response to fibroblast growth factor stimulus |
| HP:0001780 | 0.0112167292753 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of toe |
| HP:0006297 | 0.0112458624499 | 0.666666666667 | FGFR2 FGFR3 | Hypoplasia of dental enamel |
| HP:0009466 | 0.0112458624499 | 0.666666666667 | FGFR2 FGFR3 | Radial deviation of finger |
| HP:0002589 | 0.0112458624499 | 0.666666666667 | FGFR1 FGFR2 | Gastrointestinal atresia |
| HP:0045009 | 0.0112458624499 | 0.666666666667 | FGFR2 FGFR3 | Abnormal morphology of the radius |
| HP:0200006 | 0.0117104796003 | 1.0 | FGFR1 FGFR2 FGFR3 | Slanting of the palpebral fissure |
| KEGG:04144 | 0.0117748506163 | 0.666666666667 | FGFR2 FGFR3 | Endocytosis |
| GO:0071774 | 0.0117851633362 | 1.0 | FGFR1 FGFR2 FGFR3 | response to fibroblast growth factor |
| HP:0011314 | 0.0118541652721 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of long bone morphology |
| HP:0009815 | 0.0119990214944 | 1.0 | FGFR1 FGFR2 FGFR3 | Aplasia/hypoplasia of the extremities |
| GO:0019838 | 0.0125706532002 | 1.0 | FGFR1 FGFR2 FGFR3 | growth factor binding |
| HP:0011390 | 0.0126201279551 | 0.666666666667 | FGFR2 FGFR3 | Morphological abnormality of the inner ear |
| HP:0001360 | 0.0126201279551 | 0.666666666667 | FGFR1 FGFR3 | Holoprosencephaly |
| HP:0000429 | 0.0126654873819 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of the nasal alae |
| HP:0005918 | 0.012893006316 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormal finger phalanx morphology |
| HP:0000646 | 0.0130957715491 | 0.666666666667 | FGFR2 FGFR3 | Amblyopia |
| HP:0001421 | 0.0130957715491 | 0.666666666667 | FGFR2 FGFR3 | Abnormality of the musculature of the hand |
| HP:0040069 | 0.0131232337806 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormal lower limb bone morphology |
| HP:0000508 | 0.0135130087077 | 1.0 | FGFR1 FGFR2 FGFR3 | Ptosis |
| HP:0010760 | 0.0135801907106 | 0.666666666667 | FGFR1 FGFR2 | Absent toe |
| HP:0006495 | 0.0135801907106 | 0.666666666667 | FGFR2 FGFR3 | Aplasia/Hypoplasia of the ulna |
| HP:0000270 | 0.0135801907106 | 0.666666666667 | FGFR2 FGFR3 | Delayed cranial suture closure |
| HP:0009485 | 0.0135801907106 | 0.666666666667 | FGFR2 FGFR3 | Radial deviation of the hand or of fingers of the hand |
| HP:0000377 | 0.0138303276252 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of the pinna |
| HP:0000316 | 0.0139908331347 | 1.0 | FGFR1 FGFR2 FGFR3 | Hypertelorism |
| HP:0000481 | 0.0140715494797 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormal cornea morphology |
| HP:0006753 | 0.0140733842524 | 0.666666666667 | FGFR2 FGFR3 | Neoplasm of the stomach |
| HP:0000632 | 0.0140733842524 | 0.666666666667 | FGFR2 FGFR3 | Lacrimation abnormality |
| HP:0000036 | 0.0141525756763 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of the penis |
| HP:0000369 | 0.0144797908506 | 1.0 | FGFR1 FGFR2 FGFR3 | Low-set ears |
| HP:0000444 | 0.0145753509873 | 0.666666666667 | FGFR2 FGFR3 | Convex nasal ridge |
| HP:0000294 | 0.0145753509873 | 0.666666666667 | FGFR2 FGFR3 | Low anterior hairline |
| HP:0008905 | 0.0145753509873 | 0.666666666667 | FGFR1 FGFR3 | Rhizomelia |
| HP:0007370 | 0.0148120111376 | 1.0 | FGFR1 FGFR2 FGFR3 | Aplasia/Hypoplasia of the corpus callosum |
| HP:0000028 | 0.0148958527101 | 1.0 | FGFR1 FGFR2 FGFR3 | Cryptorchidism |
| HP:0001357 | 0.0150860897283 | 0.666666666667 | FGFR2 FGFR3 | Plagiocephaly |
| HP:0010535 | 0.0150860897283 | 0.666666666667 | FGFR2 FGFR3 | Sleep apnea |
| HP:0002974 | 0.0150860897283 | 0.666666666667 | FGFR2 FGFR3 | Radioulnar synostosis |
| HP:0007598 | 0.0150860897283 | 0.666666666667 | FGFR2 FGFR3 | Bilateral single transverse palmar creases |
| HP:0002242 | 0.0155780034999 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormal intestine morphology |
| HP:0001371 | 0.0156647085286 | 1.0 | FGFR1 FGFR2 FGFR3 | Flexion contracture |
| HP:0009118 | 0.0157517346871 | 1.0 | FGFR1 FGFR2 FGFR3 | Aplasia/Hypoplasia of the mandible |
| HP:0012179 | 0.0161338784795 | 0.666666666667 | FGFR2 FGFR3 | Craniofacial dystonia |
| HP:0010936 | 0.0162806686033 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of the lower urinary tract |
| HP:0009116 | 0.0165495188933 | 1.0 | FGFR1 FGFR2 FGFR3 | Aplasia/Hypoplasia involving bones of the skull |
| HP:0100261 | 0.0170041519362 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormal tendon morphology |
| HP:0000357 | 0.0172808874154 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormal location of ears |
| HP:0008050 | 0.0175606092232 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of the palpebral fissures |
| HP:0010622 | 0.017771321972 | 0.666666666667 | FGFR1 FGFR3 | Neoplasm of the skeletal system |
| GO:0004713 | 0.0180261250619 | 1.0 | FGFR1 FGFR2 FGFR3 | protein tyrosine kinase activity |
| HP:0002516 | 0.0183346678183 | 0.666666666667 | FGFR2 FGFR3 | Increased intracranial pressure |
| HP:0012640 | 0.0183346678183 | 0.666666666667 | FGFR2 FGFR3 | Abnormality of intracranial pressure |
| HP:0001191 | 0.0183346678183 | 0.666666666667 | FGFR2 FGFR3 | Abnormality of the carpal bones |
| HP:0010609 | 0.0183346678183 | 0.666666666667 | FGFR1 FGFR2 | Skin tags |
| HP:0000685 | 0.0189067773604 | 0.666666666667 | FGFR2 FGFR3 | Hypoplasia of teeth |
| HP:0000260 | 0.0189067773604 | 0.666666666667 | FGFR2 FGFR3 | Wide anterior fontanel |
| HP:0001273 | 0.0191035562841 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormal corpus callosum morphology |
| HP:0004691 | 0.0194876494112 | 0.666666666667 | FGFR1 FGFR2 | 2-3 toe syndactyly |
| HP:0009821 | 0.0194876494112 | 0.666666666667 | FGFR2 FGFR3 | Forearm undergrowth |
| HP:0100258 | 0.0194876494112 | 0.666666666667 | FGFR2 FGFR3 | Preaxial polydactyly |
| GO:0051897 | 0.0196004650773 | 1.0 | FGFR1 FGFR2 FGFR3 | positive regulation of protein kinase B signaling |
| HP:0000383 | 0.0200772827833 | 0.666666666667 | FGFR1 FGFR2 | Abnormality of periauricular region |
| HP:0025015 | 0.0202151346972 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormal vascular morphology |
| HP:0001482 | 0.0218987389569 | 0.666666666667 | FGFR1 FGFR2 | Subcutaneous nodule |
| HP:0004373 | 0.0225234057432 | 0.666666666667 | FGFR2 FGFR3 | Focal dystonia |
| HP:0008572 | 0.0225234057432 | 0.666666666667 | FGFR2 FGFR3 | External ear malformation |
| HP:0002118 | 0.022676974613 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of the cerebral ventricles |
| HP:0002648 | 0.022676974613 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of calvarial morphology |
| HP:0000587 | 0.0229000256292 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of the optic nerve |
| HP:0009122 | 0.0232373370987 | 1.0 | FGFR1 FGFR2 FGFR3 | Aplasia/hypoplasia affecting bones of the axial skeleton |
| HP:0009824 | 0.0237990042853 | 0.666666666667 | FGFR2 FGFR3 | Upper limb undergrowth |
| HP:0000973 | 0.0237990042853 | 0.666666666667 | FGFR2 FGFR3 | Cutis laxa |
| HP:0000027 | 0.0237990042853 | 0.666666666667 | FGFR1 FGFR3 | Azoospermia |
| HP:0012368 | 0.0237990042853 | 0.666666666667 | FGFR2 FGFR3 | Flat face |
| HP:0010651 | 0.0244499336669 | 0.666666666667 | FGFR1 FGFR2 | Abnormal meningeal morphology |
| CORUM:6836 | 0.0249904952816 | 0.333333333333 | FGFR1 | FGFR1c-KLB complex |
| CORUM:6834 | 0.0249904952816 | 0.333333333333 | FGFR1 | FGF21-FGFR1c-KLB complex |
| CORUM:6828 | 0.0249904952816 | 0.333333333333 | FGFR1 | FGF21-FGFR1c-KLB complex |
| CORUM:912 | 0.0249904952816 | 0.333333333333 | FGFR1 | FGFR1-KAL11 complex |
| HP:0001317 | 0.0256917079286 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormal cerebellum morphology |
| HP:0003510 | 0.0257780467151 | 0.666666666667 | FGFR1 FGFR3 | Severe short stature |
| HP:0011355 | 0.0259340813389 | 1.0 | FGFR1 FGFR2 FGFR3 | Localized skin lesion |
| HP:0011283 | 0.026177974328 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of the metencephalon |
| HP:0011282 | 0.026177974328 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of hindbrain morphology |
| HP:0000407 | 0.0266703380374 | 1.0 | FGFR1 FGFR2 FGFR3 | Sensorineural hearing impairment |
| HP:0011793 | 0.027043635032 | 1.0 | FGFR1 FGFR2 FGFR3 | Neoplasm by anatomical site |
| HP:0000765 | 0.0278006464462 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of the thorax |
| HP:0040073 | 0.028539256711 | 0.666666666667 | FGFR2 FGFR3 | Abnormal forearm bone morphology |
| HP:0000689 | 0.028539256711 | 0.666666666667 | FGFR2 FGFR3 | Dental malocclusion |
| HP:0008669 | 0.0292514239306 | 0.666666666667 | FGFR1 FGFR3 | Abnormal spermatogenesis |
| HP:0002500 | 0.0293567877248 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of the cerebral white matter |
| HP:0000164 | 0.0293567877248 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of the dentition |
| HP:0010785 | 0.029972334664 | 0.666666666667 | FGFR2 FGFR3 | Gonadal neoplasm |
| HP:0008873 | 0.029972334664 | 0.666666666667 | FGFR1 FGFR3 | Disproportionate short-limb short stature |
| HP:0200036 | 0.0307019877242 | 0.666666666667 | FGFR1 FGFR2 | Skin nodule |
| HP:0011495 | 0.0307019877242 | 0.666666666667 | FGFR2 FGFR3 | Abnormal corneal epithelium morphology |
| HP:0000277 | 0.0308333096044 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of the mandible |
| HP:0002664 | 0.0308333096044 | 1.0 | FGFR1 FGFR2 FGFR3 | Neoplasm |
| HP:0000035 | 0.0309699417001 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormal testis morphology |
| HP:0002084 | 0.0314403819239 | 0.666666666667 | FGFR1 FGFR3 | Encephalocele |
| HP:0011815 | 0.0314403819239 | 0.666666666667 | FGFR1 FGFR3 | Cephalocele |
| HP:0001166 | 0.0314403819239 | 0.666666666667 | FGFR2 FGFR3 | Arachnodactyly |
| HP:0010938 | 0.0316591597185 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of the external nose |
| HP:0100886 | 0.0323585280482 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of globe location |
| HP:0000236 | 0.0329433889933 | 0.666666666667 | FGFR2 FGFR3 | Abnormality of the anterior fontanelle |
| HP:0011354 | 0.0333548375065 | 1.0 | FGFR1 FGFR2 FGFR3 | Generalized abnormality of skin |
| HP:0000486 | 0.0336432066673 | 1.0 | FGFR1 FGFR2 FGFR3 | Strabismus |
| HP:0000599 | 0.0344813463748 | 0.666666666667 | FGFR2 FGFR3 | Abnormality of the frontal hairline |
| HP:0000926 | 0.0344813463748 | 0.666666666667 | FGFR1 FGFR3 | Platyspondyly |
| HP:0000290 | 0.0351100068041 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of the forehead |
| HP:0002092 | 0.0352634284647 | 0.666666666667 | FGFR1 FGFR3 | Pulmonary arterial hypertension |
| HP:0004890 | 0.0352634284647 | 0.666666666667 | FGFR1 FGFR3 | Elevated pulmonary artery pressure |
| HP:0011389 | 0.0354083909388 | 1.0 | FGFR1 FGFR2 FGFR3 | Functional abnormality of the inner ear |
| HP:0002683 | 0.0355582148779 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of the calvaria |
| HP:0030791 | 0.0358591294675 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormal jaw morphology |
| HP:0003745 | 0.0360542445711 | 0.666666666667 | FGFR1 FGFR3 | Sporadic |
| HP:0000422 | 0.0367720496654 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of the nasal bridge |
| HP:0001331 | 0.0368537935068 | 0.666666666667 | FGFR1 FGFR2 | Absent septum pellucidum |
| HP:0000359 | 0.03707976437 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of the inner ear |
| HP:0000549 | 0.0372342633882 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormal conjugate eye movement |
| HP:0012210 | 0.0372342633882 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormal renal morphology |
| HP:0005105 | 0.0373891909751 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormal nasal morphology |
| HP:0002996 | 0.0384790851177 | 0.666666666667 | FGFR2 FGFR3 | Limited elbow movement |
| HP:0001792 | 0.0384790851177 | 0.666666666667 | FGFR1 FGFR2 | Small nail |
| HP:0002983 | 0.0384790851177 | 0.666666666667 | FGFR2 FGFR3 | Micromelia |
| HP:0011039 | 0.0393048254184 | 0.666666666667 | FGFR2 FGFR3 | Abnormality of the helix |
| HP:0008551 | 0.0393048254184 | 0.666666666667 | FGFR2 FGFR3 | Microtia |
| HP:0000774 | 0.0401392937999 | 0.666666666667 | FGFR2 FGFR3 | Narrow chest |
| HP:0001739 | 0.0401392937999 | 0.666666666667 | FGFR1 FGFR2 | Abnormality of the nasopharynx |
| HP:0010993 | 0.0409072271866 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormality of the cerebral subcortex |
| HP:0001238 | 0.0409824890748 | 0.666666666667 | FGFR2 FGFR3 | Slender finger |
| HP:0007375 | 0.041834410056 | 0.666666666667 | FGFR1 FGFR2 | Abnormality of the septum pellucidum |
| HP:0000174 | 0.0424077548495 | 1.0 | FGFR1 FGFR2 FGFR3 | Abnormal palate morphology |
| HP:0008772 | 0.0426950555564 | 0.666666666667 | FGFR2 FGFR3 | Aplasia/Hypoplasia of the external ear |
| HP:0007495 | 0.0435644243888 | 0.666666666667 | FGFR2 FGFR3 | Prematurely aged appearance |
| HP:0003508 | 0.044442515366 | 0.666666666667 | FGFR1 FGFR3 | Proportionate short stature |
| HP:0000505 | 0.0446392984448 | 1.0 | FGFR1 FGFR2 FGFR3 | Visual impairment |
| HP:0002650 | 0.0451651492781 | 1.0 | FGFR1 FGFR2 FGFR3 | Scoliosis |
| HP:0003498 | 0.0453293273008 | 0.666666666667 | FGFR1 FGFR3 | Disproportionate short stature |
| HP:0005107 | 0.0453293273008 | 0.666666666667 | FGFR2 FGFR3 | Abnormal sacrum morphology |
| HP:0008771 | 0.0462248590062 | 0.666666666667 | FGFR2 FGFR3 | Aplasia/Hypoplasia of the ear |
| HP:0000324 | 0.0462248590062 | 0.666666666667 | FGFR2 FGFR3 | Facial asymmetry |
| HP:0003019 | 0.0462248590062 | 0.666666666667 | FGFR2 FGFR3 | Abnormality of the wrist |
| GO:0051896 | 0.047104416733 | 1.0 | FGFR1 FGFR2 FGFR3 | regulation of protein kinase B signaling |
| HP:0001053 | 0.0480420769795 | 0.666666666667 | FGFR2 FGFR3 | Hypopigmented skin patches |
| HP:0001028 | 0.0489637608732 | 0.666666666667 | FGFR1 FGFR2 | Hemangioma |
| HP:0001832 | 0.0489637608732 | 0.666666666667 | FGFR1 FGFR2 | Abnormal metatarsal morphology |
| REAC:R-HSA-2023837 | 0.0498572752401 | 0.333333333333 | FGFR2 | Signaling by FGFR2 amplification mutants |
| REAC:R-HSA-2033515 | 0.0498572752401 | 0.333333333333 | FGFR3 | t(4;14) translocations of FGFR3 |
| REAC:R-HSA-8853333 | 0.0498572752401 | 0.333333333333 | FGFR2 | Signaling by FGFR2 fusions |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| FGFR2 | FGFR3 | 0.995 | 0.924 | bioplex (FGFR2) bioplex_WMM |
| FGFR2 | FGFR1 | 0.707 | 0.729 | bioplex (FGFR2) bioplex_WMM |
| FGFR1 | FGFR3 | 0.008 | 0.068 | bioplex_WMM WMM_only |
Images
Click to enlarge
Complex HuMAP2_06274 has an average edge precision of 0.574 which is ranked 2060 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| FGFR1 | HuMAP2_02095 HuMAP2_06014 HuMAP2_06274 HuMAP2_06605 |
| FGFR2 | HuMAP2_02095 HuMAP2_06014 HuMAP2_06274 HuMAP2_06605 |
| FGFR3 | HuMAP2_02095 HuMAP2_02142 HuMAP2_06014 HuMAP2_06274 HuMAP2_06605 |