hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06285
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CKMT1A | Creatine kinase U-type, mitochondrial (EC 2.7.3.2) (Acidic-type mitochondrial creatine kinase) (Mia-CK) (Ubiquitous mitochondrial creatine kinase) (U-MtCK) | UniProt NCBI |
| MICALL1 | MICAL-like protein 1 (Molecule interacting with Rab13) (MIRab13) | UniProt NCBI |
| RAB8A | Ras-related protein Rab-8A (Oncogene c-mel) | UniProt NCBI |
| MICALL2 | MICAL-like protein 2 (Junctional Rab13-binding protein) (Molecule interacting with CasL-like 2) (MICAL-L2) | UniProt NCBI |
| SLC25A46 | Solute carrier family 25 member 46 | UniProt NCBI |
| RAB8B | Ras-related protein Rab-8B | UniProt NCBI |
| NARS2 | Probable asparagine--tRNA ligase, mitochondrial (EC 6.1.1.22) (Asparaginyl-tRNA synthetase) (AsnRS) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04530 | 0.000819121924932 | 0.5 | RAB8B MICALL2 RAB8A | Tight junction |
| GO:0055037 | 0.0028699930952 | 0.666666666667 | MICALL1 RAB8B MICALL2 RAB8A | recycling endosome |
| REAC:R-HSA-8854214 | 0.019874448248 | 0.333333333333 | RAB8B RAB8A | TBC/RABGAPs |
| GO:0055038 | 0.0332327932613 | 0.5 | MICALL1 RAB8A RAB8B | recycling endosome membrane |
| REAC:R-HSA-8873719 | 0.0414781208299 | 0.333333333333 | RAB8B RAB8A | RAB geranylgeranylation |
| WP:WP2858 | 0.0437238028604 | 0.333333333333 | RAB8B NARS2 | Ectoderm Differentiation |
| CORUM:7333 | 0.0499726005494 | 0.166666666667 | MICALL1 | MICALL1-RAB13 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RAB8B | RAB8A | 0.89 | 0.818 | bioplex (RAB8B) bioplex_WMM gupta_WMM |
| RAB8B | MICALL2 | 0.639 | 0.686 | bioplex (RAB8B) bioplex_WMM |
| MICALL1 | RAB8B | 0.188 | 0.439 | bioplex (RAB8B) bioplex_WMM |
| RAB8B | CKMT1A | 0.031 | 0.24 | bioplex (RAB8B) fraction |
| RAB8B | NARS2 | 0.028 | 0.231 | bioplex (RAB8B) bioplex_WMM |
| RAB8A | CKMT1A | 0.021 | 0.188 | fraction |
| CKMT1A | SLC25A46 | 0.02 | 0.185 | fraction |
| MICALL1 | RAB8A | 0.009 | 0.089 | bioplex_WMM boldt (RAB8A) gupta_WMM boldt_WMM |
| MICALL1 | MICALL2 | 0.008 | 0.093 | bioplex_WMM WMM_only |
| RAB8A | MICALL2 | 0.008 | 0.087 | bioplex_WMM WMM_only |
| MICALL2 | NARS2 | 0.008 | 0.013 | bioplex_WMM WMM_only |
| MICALL1 | NARS2 | 0.007 | 0.004 | bioplex_WMM WMM_only |
| RAB8A | NARS2 | 0.007 | 0.005 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_06285 has an average edge precision of 0.237 which is ranked 5587 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| CKMT1A | HuMAP2_04485 HuMAP2_06285 HuMAP2_06649 |
| MICALL1 | HuMAP2_00974 HuMAP2_01102 HuMAP2_01103 HuMAP2_01661 HuMAP2_02945 HuMAP2_04010 HuMAP2_06001 HuMAP2_06285 HuMAP2_06775 |
| RAB8A | HuMAP2_01064 HuMAP2_01661 HuMAP2_06144 HuMAP2_06285 |
| MICALL2 | HuMAP2_01661 HuMAP2_06001 HuMAP2_06144 HuMAP2_06285 |
| SLC25A46 | HuMAP2_06285 |
| RAB8B | HuMAP2_01064 HuMAP2_01661 HuMAP2_06001 HuMAP2_06144 HuMAP2_06285 |
| NARS2 | HuMAP2_06001 HuMAP2_06285 |