hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06304
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RPIA | Ribose-5-phosphate isomerase (EC 5.3.1.6) (Phosphoriboisomerase) | UniProt NCBI |
| WDR5B | WD repeat-containing protein 5B | UniProt NCBI |
| DHH | Desert hedgehog protein (DHH) (HHG-3) [Cleaved into: Desert hedgehog protein N-product; Desert hedgehog protein C-product] | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0001271 | 0.00995061979035 | 0.666666666667 | RPIA DHH | Polyneuropathy |
| HP:0007141 | 0.0140733842524 | 0.666666666667 | RPIA DHH | Sensorimotor neuropathy |
| REAC:R-HSA-5659996 | 0.0498572752401 | 0.333333333333 | RPIA | RPIA deficiency: failed conversion of R5P to RU5P |
| REAC:R-HSA-6791461 | 0.0498572752401 | 0.333333333333 | RPIA | RPIA deficiency: failed conversion of RU5P to R5P |
| WP:WP134 | 0.0499785733994 | 0.333333333333 | RPIA | Pentose Phosphate Metabolism |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| WDR5B | RPIA | 0.321 | 0.512 | bioplex (WDR5B) bioplex_WMM |
| DHH | RPIA | 0.049 | 0.294 | bioplex (DHH) bioplex_WMM |
Images
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Complex HuMAP2_06304 has an average edge precision of 0.403 which is ranked 3283 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| RPIA | HuMAP2_00048 HuMAP2_03817 HuMAP2_06304 HuMAP2_06579 |
| WDR5B | HuMAP2_00048 HuMAP2_03817 HuMAP2_03871 HuMAP2_06304 HuMAP2_06579 |
| DHH | HuMAP2_00048 HuMAP2_03817 HuMAP2_05477 HuMAP2_06304 HuMAP2_06405 HuMAP2_06579 |