hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06314
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| POFUT2 | GDP-fucose protein O-fucosyltransferase 2 (EC 2.4.1.221) (Peptide-O-fucosyltransferase 2) (O-FucT-2) | UniProt NCBI |
| DNMT1 | DNA (cytosine-5)-methyltransferase 1 (Dnmt1) (EC 2.1.1.37) (CXXC-type zinc finger protein 9) (DNA methyltransferase HsaI) (DNA MTase HsaI) (M.HsaI) (MCMT) | UniProt NCBI |
| DENR | Density-regulated protein (DRP) (Protein DRP1) (Smooth muscle cell-associated protein 3) (SMAP-3) | UniProt NCBI |
| DOCK11 | Dedicator of cytokinesis protein 11 (Activated Cdc42-associated guanine nucleotide exchange factor) (ACG) (Zizimin-2) | UniProt NCBI |
| MCTS1 | Malignant T-cell-amplified sequence 1 (MCT-1) (Multiple copies T-cell malignancies) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0002188 | 0.0135228859698 | 0.4 | MCTS1 DENR | translation reinitiation |
| CORUM:862 | 0.0499494897235 | 0.2 | DNMT1 | DNMT1-EHMT2 complex |
| CORUM:6336 | 0.0499494897235 | 0.2 | DNMT1 | CTNNB1-DNMT1 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| DENR | MCTS1 | 1.0 | 0.949 | bioplex (DENR) bioplex_WMM gupta_WMM fraction |
| DENR | DOCK11 | 0.198 | 0.45 | bioplex (DENR) bioplex_WMM |
| POFUT2 | MCTS1 | 0.038 | 0.261 | fraction |
| DENR | DNMT1 | 0.021 | 0.189 | bioplex_WMM youn_WMM gupta_WMM fraction |
| DENR | POFUT2 | 0.013 | 0.143 | fraction |
| DOCK11 | MCTS1 | 0.008 | 0.09 | bioplex_WMM WMM_only |
| MCTS1 | DNMT1 | 0.007 | 0.003 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| POFUT2 | DNMT1 | 0.006 | 0.009 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_06314 has an average edge precision of 0.262 which is ranked 5200 out of all 6965 complexes.
Related Complexes