hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06324
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| KAT7 | Histone acetyltransferase KAT7 (EC 2.3.1.48) (Histone acetyltransferase binding to ORC1) (Lysine acetyltransferase 7) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (MYST-2) | UniProt NCBI |
| BRD1 | Bromodomain-containing protein 1 (BR140-like protein) (Bromodomain and PHD finger-containing protein 2) | UniProt NCBI |
| JADE1 | Protein Jade-1 (Jade family PHD finger protein 1) (PHD finger protein 17) | UniProt NCBI |
| JADE3 | Protein Jade-3 (Jade family PHD finger protein 3) (PHD finger protein 16) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-3214847 | 1.47230432248e-06 | 1.0 | KAT7 BRD1 JADE3 JADE1 | HATs acetylate histones |
| GO:0043966 | 5.61829777936e-06 | 1.0 | KAT7 BRD1 JADE3 JADE1 | histone H3 acetylation |
| GO:0043983 | 7.26438828159e-06 | 0.75 | KAT7 JADE1 JADE3 | histone H4-K12 acetylation |
| REAC:R-HSA-4839726 | 1.93476074015e-05 | 1.0 | KAT7 BRD1 JADE3 JADE1 | Chromatin organization |
| REAC:R-HSA-3247509 | 1.93476074015e-05 | 1.0 | KAT7 BRD1 JADE3 JADE1 | Chromatin modifying enzymes |
| CORUM:2858 | 3.01612206104e-05 | 0.5 | KAT7 JADE1 | ING5 complex (ING5, JADE1, KAT7, MEAF6) |
| CORUM:2848 | 3.01612206104e-05 | 0.5 | KAT7 JADE3 | ING4 complex (ING4, JADE3, KAT7, MEAF6) |
| CORUM:1352 | 3.01612206104e-05 | 0.5 | KAT7 JADE1 | ING4 complex (ING4, JADE1, KAT7, MEAF6) |
| CORUM:7255 | 3.01612206104e-05 | 0.5 | KAT7 JADE3 | ING5 complex (ING5, JADE3, KAT7, MEAF6) |
| GO:0000123 | 3.47984386015e-05 | 1.0 | KAT7 BRD1 JADE3 JADE1 | histone acetyltransferase complex |
| GO:1902493 | 5.68877655611e-05 | 1.0 | KAT7 BRD1 JADE3 JADE1 | acetyltransferase complex |
| GO:0031248 | 5.68877655611e-05 | 1.0 | KAT7 BRD1 JADE3 JADE1 | protein acetyltransferase complex |
| GO:0016573 | 0.000125895977869 | 1.0 | KAT7 BRD1 JADE3 JADE1 | histone acetylation |
| GO:0018393 | 0.000135718631087 | 1.0 | KAT7 BRD1 JADE3 JADE1 | internal peptidyl-lysine acetylation |
| GO:0006475 | 0.000162788555852 | 1.0 | KAT7 BRD1 JADE3 JADE1 | internal protein amino acid acetylation |
| GO:0043981 | 0.000165189908538 | 0.75 | KAT7 JADE1 JADE3 | histone H4-K5 acetylation |
| GO:0043982 | 0.000165189908538 | 0.75 | KAT7 JADE1 JADE3 | histone H4-K8 acetylation |
| GO:0018394 | 0.000168654810117 | 1.0 | KAT7 BRD1 JADE3 JADE1 | peptidyl-lysine acetylation |
| GO:0006473 | 0.000455512457831 | 1.0 | KAT7 BRD1 JADE3 JADE1 | protein acetylation |
| GO:0043543 | 0.00107888479641 | 1.0 | KAT7 BRD1 JADE3 JADE1 | protein acylation |
| GO:0018205 | 0.00665909549353 | 1.0 | KAT7 BRD1 JADE3 JADE1 | peptidyl-lysine modification |
| GO:0043967 | 0.00848863295691 | 0.75 | KAT7 JADE1 JADE3 | histone H4 acetylation |
| GO:0016570 | 0.0111323368581 | 1.0 | KAT7 BRD1 JADE3 JADE1 | histone modification |
| GO:0016569 | 0.0133451908966 | 1.0 | KAT7 BRD1 JADE3 JADE1 | covalent chromatin modification |
| CORUM:6342 | 0.0499140284799 | 0.25 | JADE1 | Jade-1-NPHP4 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| KAT7 | JADE1 | 0.995 | 0.924 | hein_WMM bioplex (JADE1,KAT7) bioplex_WMM |
| KAT7 | JADE3 | 0.662 | 0.698 | hein_WMM bioplex (KAT7) bioplex_WMM youn_WMM |
| KAT7 | BRD1 | 0.153 | 0.412 | hein_WMM bioplex (KAT7) bioplex_WMM youn_WMM |
| JADE1 | JADE3 | 0.011 | 0.141 | hein_WMM bioplex_WMM WMM_only |
| JADE3 | BRD1 | 0.01 | 0.103 | hein_WMM bioplex_WMM WMM_only |
| JADE1 | BRD1 | 0.009 | 0.108 | hein_WMM bioplex_WMM WMM_only |
Images
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Complex HuMAP2_06324 has an average edge precision of 0.398 which is ranked 3353 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| KAT7 | HuMAP2_00963 HuMAP2_02043 HuMAP2_06324 HuMAP2_06383 |
| BRD1 | HuMAP2_06324 HuMAP2_06383 |
| JADE1 | HuMAP2_00963 HuMAP2_06324 HuMAP2_06383 |
| JADE3 | HuMAP2_03532 HuMAP2_05301 HuMAP2_06324 HuMAP2_06383 |