hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06334
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| HAUS6 | HAUS augmin-like complex subunit 6 | UniProt NCBI |
| HAUS7 | HAUS augmin-like complex subunit 7 (26S proteasome-associated UCH37-interacting protein 1) (UCHL5-interacting protein) (X-linked protein STS1769) | UniProt NCBI |
| HAUS1 | HAUS augmin-like complex subunit 1 (Coiled-coil domain-containing protein 5) (Enhancer of invasion-cluster) (HEI-C) | UniProt NCBI |
| HAUS2 | HAUS augmin-like complex subunit 2 (Centrosomal protein of 27 kDa) (Cep27) | UniProt NCBI |
| HAUS4 | HAUS augmin-like complex subunit 4 | UniProt NCBI |
| HAUS3 | HAUS augmin-like complex subunit 3 | UniProt NCBI |
| HAUS5 | HAUS augmin-like complex subunit 5 | UniProt NCBI |
| HAUS8 | HAUS augmin-like complex subunit 8 (HEC1/NDC80-interacting centrosome-associated protein 1) (Sarcoma antigen NY-SAR-48) | UniProt NCBI |
| GP1BB | Platelet glycoprotein Ib beta chain (GP-Ib beta) (GPIb-beta) (GPIbB) (Antigen CD42b-beta) (CD antigen CD42c) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0070652 | 7.50686889053e-24 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | HAUS complex |
| CORUM:6435 | 4.61796517245e-23 | 0.777777777778 | HAUS3 HAUS7 HAUS5 HAUS6 HAUS2 HAUS8 HAUS1 | HAUS augmin-like complex |
| REAC:R-HSA-380284 | 1.94382528471e-16 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | Loss of proteins required for interphase microtubule organization from the centrosome |
| REAC:R-HSA-380259 | 1.94382528471e-16 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | Loss of Nlp from mitotic centrosomes |
| REAC:R-HSA-8854518 | 2.81295260136e-16 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | AURKA Activation by TPX2 |
| REAC:R-HSA-380270 | 7.76951260456e-16 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | Recruitment of mitotic centrosome proteins and complexes |
| REAC:R-HSA-380287 | 7.76951260456e-16 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | Centrosome maturation |
| REAC:R-HSA-2565942 | 1.29791975725e-15 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | Regulation of PLK1 Activity at G2/M Transition |
| REAC:R-HSA-380320 | 2.30697053655e-15 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | Recruitment of NuMA to mitotic centrosomes |
| REAC:R-HSA-5620912 | 3.6164406664e-15 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | Anchoring of the basal body to the plasma membrane |
| GO:0051225 | 5.79049604675e-13 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | spindle assembly |
| GO:0097711 | 8.31336369814e-13 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | ciliary basal body-plasma membrane docking |
| REAC:R-HSA-69275 | 1.07321659849e-12 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | G2/M Transition |
| REAC:R-HSA-5617833 | 1.1200655496e-12 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | Cilium Assembly |
| REAC:R-HSA-68877 | 1.1200655496e-12 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | Mitotic Prometaphase |
| REAC:R-HSA-453274 | 1.1686934902e-12 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | Mitotic G2-G2/M phases |
| GO:0007098 | 2.62683040645e-12 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | centrosome cycle |
| GO:0031023 | 5.0858206092e-12 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | microtubule organizing center organization |
| GO:0005875 | 1.55241134129e-11 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | microtubule associated complex |
| REAC:R-HSA-1852241 | 2.42120688559e-11 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | Organelle biogenesis and maintenance |
| GO:0007051 | 2.80120884084e-11 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | spindle organization |
| GO:0140056 | 2.96460459391e-11 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | organelle localization by membrane tethering |
| GO:0022406 | 4.85316150523e-11 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | membrane docking |
| GO:0010389 | 1.44399538143e-10 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | regulation of G2/M transition of mitotic cell cycle |
| REAC:R-HSA-68886 | 2.74693103939e-10 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | M Phase |
| GO:1902749 | 2.9334206604e-10 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | regulation of cell cycle G2/M phase transition |
| GO:0000086 | 1.02655324677e-09 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | G2/M transition of mitotic cell cycle |
| GO:0044839 | 1.92120582911e-09 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | cell cycle G2/M phase transition |
| REAC:R-HSA-69278 | 3.42296831398e-09 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | Cell Cycle, Mitotic |
| REAC:R-HSA-1640170 | 1.45311860956e-08 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | Cell Cycle |
| GO:0060271 | 1.83937185998e-08 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | cilium assembly |
| GO:0044782 | 2.79258313883e-08 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | cilium organization |
| GO:1901990 | 3.61798940822e-08 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | regulation of mitotic cell cycle phase transition |
| GO:1901987 | 6.32727636447e-08 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | regulation of cell cycle phase transition |
| GO:0120031 | 2.71334139071e-07 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | plasma membrane bounded cell projection assembly |
| GO:0005813 | 3.0741763744e-07 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | centrosome |
| GO:0030031 | 3.18468288789e-07 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | cell projection assembly |
| GO:0000226 | 3.35695265573e-07 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | microtubule cytoskeleton organization |
| GO:0044772 | 3.99145214857e-07 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | mitotic cell cycle phase transition |
| GO:0051640 | 5.5815785913e-07 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | organelle localization |
| GO:0044770 | 6.67275362331e-07 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | cell cycle phase transition |
| GO:0007346 | 8.59165046808e-07 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | regulation of mitotic cell cycle |
| GO:0005815 | 2.80253368875e-06 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | microtubule organizing center |
| GO:0010564 | 3.07633353367e-06 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | regulation of cell cycle process |
| GO:0007017 | 4.04296322407e-06 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | microtubule-based process |
| GO:0070925 | 7.56682579744e-06 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | organelle assembly |
| GO:1903047 | 1.1580492562e-05 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | mitotic cell cycle process |
| GO:0000278 | 3.92963905955e-05 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | mitotic cell cycle |
| GO:0051726 | 7.35458501042e-05 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | regulation of cell cycle |
| GO:0015630 | 9.80046957858e-05 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | microtubule cytoskeleton |
| GO:0120036 | 0.000184350691284 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | plasma membrane bounded cell projection organization |
| GO:0030030 | 0.000200958578249 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | cell projection organization |
| GO:0007010 | 0.000217175038047 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | cytoskeleton organization |
| GO:0022402 | 0.000350731570528 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | cell cycle process |
| GO:0044430 | 0.000675124390925 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | cytoskeletal part |
| GO:0007049 | 0.00137165375775 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | cell cycle |
| GO:0005856 | 0.00371422709577 | 0.888888888889 | HAUS3 HAUS2 HAUS7 HAUS5 HAUS4 HAUS6 HAUS8 HAUS1 | cytoskeleton |
| CORUM:0000000 | 0.0319384059855 | 0.777777777778 | HAUS3 HAUS7 HAUS5 HAUS6 HAUS2 HAUS8 HAUS1 | CORUM root |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| HAUS7 | HAUS4 | 1.0 | 0.949 | hein_WMM bioplex (HAUS7) bioplex_WMM youn_WMM hein (HAUS4) gupta_WMM |
| HAUS7 | HAUS1 | 1.0 | 0.949 | hein_WMM bioplex (HAUS7) bioplex_WMM youn_WMM hein (HAUS1) gupta_WMM |
| HAUS7 | HAUS2 | 1.0 | 0.949 | hein_WMM bioplex (HAUS7) bioplex_WMM youn_WMM hein (HAUS2) gupta_WMM |
| HAUS7 | HAUS3 | 1.0 | 0.949 | hein_WMM bioplex (HAUS7) bioplex_WMM youn_WMM gupta_WMM |
| HAUS7 | HAUS8 | 1.0 | 0.949 | hein_WMM bioplex (HAUS7) bioplex_WMM youn_WMM gupta_WMM |
| HAUS7 | HAUS5 | 1.0 | 0.949 | hein_WMM bioplex (HAUS7) bioplex_WMM youn_WMM gupta_WMM |
| HAUS7 | HAUS6 | 1.0 | 0.949 | hein_WMM bioplex (HAUS7) bioplex_WMM youn_WMM gupta_WMM |
| HAUS1 | HAUS4 | 0.997 | 0.934 | hein_WMM bioplex_WMM boldt youn_WMM hein (HAUS1,HAUS4) gupta_WMM boldt_WMM |
| HAUS2 | HAUS3 | 0.985 | 0.899 | hein_WMM bioplex_WMM youn_WMM hein (HAUS2) gupta_WMM |
| HAUS2 | HAUS8 | 0.978 | 0.894 | hein_WMM bioplex_WMM youn_WMM hein (HAUS2) gupta_WMM |
| HAUS4 | HAUS2 | 0.963 | 0.871 | hein_WMM bioplex_WMM youn_WMM hein (HAUS2,HAUS4) gupta_WMM |
| HAUS2 | HAUS5 | 0.944 | 0.856 | hein_WMM bioplex_WMM youn_WMM hein (HAUS2) gupta_WMM |
| HAUS1 | HAUS2 | 0.905 | 0.828 | hein_WMM bioplex_WMM youn_WMM hein (HAUS1,HAUS2) gupta_WMM |
| HAUS4 | HAUS3 | 0.851 | 0.791 | hein_WMM bioplex_WMM youn_WMM hein (HAUS4) gupta_WMM |
| HAUS4 | HAUS5 | 0.797 | 0.763 | hein_WMM bioplex_WMM youn_WMM hein (HAUS4) gupta_WMM |
| HAUS1 | HAUS3 | 0.756 | 0.747 | hein_WMM bioplex_WMM youn_WMM hein (HAUS1) gupta_WMM |
| HAUS4 | HAUS8 | 0.681 | 0.708 | hein_WMM bioplex_WMM youn_WMM hein (HAUS4) gupta_WMM |
| HAUS2 | HAUS6 | 0.632 | 0.681 | hein_WMM bioplex_WMM youn_WMM hein (HAUS2) gupta_WMM |
| HAUS6 | HAUS8 | 0.383 | 0.55 | hein_WMM bioplex (HAUS8) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| HAUS4 | HAUS6 | 0.33 | 0.52 | hein_WMM bioplex_WMM youn_WMM hein (HAUS4) gupta_WMM |
| HAUS1 | HAUS5 | 0.312 | 0.505 | hein_WMM bioplex_WMM youn_WMM hein (HAUS1) gupta_WMM |
| HAUS1 | HAUS6 | 0.161 | 0.418 | hein_WMM bioplex_WMM youn_WMM hein (HAUS1) gupta_WMM |
| HAUS1 | HAUS8 | 0.155 | 0.416 | hein_WMM bioplex_WMM youn_WMM hein (HAUS1) gupta_WMM |
| HAUS7 | GP1BB | 0.047 | 0.292 | bioplex (HAUS7) bioplex_WMM |
| HAUS3 | HAUS8 | 0.022 | 0.205 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| HAUS5 | HAUS8 | 0.021 | 0.187 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| HAUS3 | HAUS5 | 0.018 | 0.178 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| HAUS6 | HAUS3 | 0.016 | 0.157 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| HAUS6 | HAUS5 | 0.016 | 0.154 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| HAUS2 | GP1BB | 0.008 | 0.031 | bioplex_WMM WMM_only |
| GP1BB | HAUS3 | 0.007 | 0.007 | bioplex_WMM WMM_only |
| GP1BB | HAUS8 | 0.007 | 0.003 | bioplex_WMM WMM_only |
| HAUS1 | GP1BB | 0.007 | 0.004 | bioplex_WMM WMM_only |
| HAUS4 | GP1BB | 0.007 | 0.003 | bioplex_WMM WMM_only |
| GP1BB | HAUS5 | 0.006 | 0.002 | bioplex_WMM WMM_only |
| GP1BB | HAUS6 | 0.006 | 0.003 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_06334 has an average edge precision of 0.535 which is ranked 2307 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| HAUS6 | HuMAP2_04538 HuMAP2_05337 HuMAP2_06334 |
| HAUS7 | HuMAP2_00474 HuMAP2_03612 HuMAP2_04538 HuMAP2_05337 HuMAP2_06334 |
| HAUS1 | HuMAP2_00474 HuMAP2_04538 HuMAP2_05337 HuMAP2_06334 |
| HAUS2 | HuMAP2_00474 HuMAP2_04538 HuMAP2_05337 HuMAP2_06334 |
| HAUS4 | HuMAP2_00474 HuMAP2_04538 HuMAP2_05337 HuMAP2_06334 |
| HAUS3 | HuMAP2_04538 HuMAP2_05337 HuMAP2_06334 |
| HAUS5 | HuMAP2_04538 HuMAP2_05337 HuMAP2_06334 |
| HAUS8 | HuMAP2_04538 HuMAP2_05337 HuMAP2_06334 |
| GP1BB | HuMAP2_03612 HuMAP2_05337 HuMAP2_06334 |