hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06339
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SYNRG | Synergin gamma (AP1 subunit gamma-binding protein 1) (Gamma-synergin) | UniProt NCBI |
| BRCA2 | Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein) | UniProt NCBI |
| DNAJB8 | DnaJ homolog subfamily B member 8 | UniProt NCBI |
| AP1G2 | AP-1 complex subunit gamma-like 2 (Gamma2-adaptin) (G2ad) | UniProt NCBI |
| MLF1 | Myeloid leukemia factor 1 (Myelodysplasia-myeloid leukemia factor 1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0004808 | 0.0259615168254 | 0.4 | MLF1 BRCA2 | Acute myeloid leukemia |
| GO:0030121 | 0.0450641792523 | 0.4 | SYNRG AP1G2 | AP-1 adaptor complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SYNRG | MLF1 | 0.577 | 0.659 | bioplex (MLF1) bioplex_WMM |
| MLF1 | BRCA2 | 0.075 | 0.357 | bioplex (MLF1) bioplex_WMM |
| MLF1 | DNAJB8 | 0.05 | 0.297 | bioplex (DNAJB8) bioplex_WMM |
| SYNRG | AP1G2 | 0.042 | 0.27 | hein_WMM bioplex (AP1G2) bioplex_WMM |
| SYNRG | BRCA2 | 0.007 | 0.002 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| BRCA2 | AP1G2 | 0.004 | 0.018 | bioplex (AP1G2) bioplex_WMM |
Images
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Complex HuMAP2_06339 has an average edge precision of 0.267 which is ranked 5083 out of all 6965 complexes.
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