hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06341
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| TIMM8B | Mitochondrial import inner membrane translocase subunit Tim8 B (DDP-like protein) (Deafness dystonia protein 2) | UniProt NCBI |
| TIMM8A | Mitochondrial import inner membrane translocase subunit Tim8 A (Deafness dystonia protein 1) (X-linked deafness dystonia protein) | UniProt NCBI |
| TIMM13 | Mitochondrial import inner membrane translocase subunit Tim13 | UniProt NCBI |
| STPG3 | Protein STPG3 (Sperm-tail PG-rich repeat-containing protein 3) | UniProt NCBI |
| PDYN | Proenkephalin-B (Beta-neoendorphin-dynorphin) (Preprodynorphin) [Cleaved into: Alpha-neoendorphin; Beta-neoendorphin; Big dynorphin (Big Dyn); Dynorphin A(1-17) (Dyn-A17) (Dynorphin A); Dynorphin A(1-13); Dynorphin A(1-8); Leu-enkephalin; Rimorphin (Dynorphin B) (Dyn-B) (Dynorphin B(1-13)); Leumorphin (Dynorphin B-29)] | UniProt NCBI |
| ACAD11 | Acyl-CoA dehydrogenase family member 11 (ACAD-11) (EC 1.3.99.-) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6452 | 8.39001385941e-06 | 0.333333333333 | TIMM13 TIMM8A | TIMM8A-TIMM13 complex |
| CORUM:7198 | 2.51655344529e-05 | 0.333333333333 | TIMM13 TIMM8A | TIMM8A-TIMM13-TIMM23 complex |
| REAC:R-HSA-1268020 | 0.000202041038028 | 0.5 | TIMM8B TIMM8A TIMM13 | Mitochondrial protein import |
| GO:0072321 | 0.000217734118711 | 0.5 | TIMM8B TIMM8A TIMM13 | chaperone-mediated protein transport |
| REAC:R-HSA-9609507 | 0.00296089666153 | 0.5 | TIMM8B TIMM8A TIMM13 | Protein localization |
| MIRNA:hsa-miR-6743-3p | 0.00674179049689 | 0.333333333333 | PDYN TIMM8A | hsa-miR-6743-3p |
| GO:0005758 | 0.0499477329172 | 0.5 | TIMM8B TIMM8A TIMM13 | mitochondrial intermembrane space |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| TIMM8B | TIMM13 | 0.952 | 0.858 | hein_WMM bioplex_WMM Guru boldt Malo fraction boldt_WMM |
| PDYN | TIMM8B | 0.945 | 0.857 | bioplex (PDYN) bioplex_WMM |
| PDYN | TIMM13 | 0.303 | 0.497 | bioplex (PDYN) bioplex_WMM |
| PDYN | TIMM8A | 0.091 | 0.354 | bioplex (PDYN) bioplex_WMM |
| TIMM8A | TIMM13 | 0.077 | 0.352 | hein_WMM bioplex_WMM boldt fraction boldt_WMM |
| TIMM13 | STPG3 | 0.069 | 0.347 | bioplex (STPG3) bioplex_WMM |
| PDYN | ACAD11 | 0.062 | 0.341 | bioplex (PDYN) bioplex_WMM |
| TIMM8B | TIMM8A | 0.019 | 0.184 | bioplex_WMM boldt boldt_WMM |
| TIMM8A | STPG3 | 0.008 | 0.044 | bioplex (STPG3) bioplex_WMM |
| TIMM8B | ACAD11 | 0.007 | 0.003 | bioplex_WMM WMM_only |
| TIMM8A | ACAD11 | 0.007 | 0.004 | bioplex_WMM WMM_only |
| TIMM13 | ACAD11 | 0.007 | 0.004 | bioplex_WMM WMM_only |
| TIMM8B | STPG3 | 0.005 | 0.009 | bioplex (STPG3) |
Images
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Complex HuMAP2_06341 has an average edge precision of 0.296 which is ranked 4645 out of all 6965 complexes.
Related Complexes