hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06343
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RAB3IP | Rab-3A-interacting protein (Rab3A-interacting protein) (Rabin-3) (SSX2-interacting protein) | UniProt NCBI |
| PPFIA3 | Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3) | UniProt NCBI |
| RAB3IL1 | Guanine nucleotide exchange factor for Rab-3A (Rab-3A-interacting-like protein 1) (Rab3A-interacting-like protein 1) (Rabin3-like 1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-8876198 | 0.0238137546255 | 0.666666666667 | RAB3IP RAB3IL1 | RAB GEFs exchange GTP for GDP on RABs |
| REAC:R-HSA-9007101 | 0.0444303896492 | 0.666666666667 | RAB3IP RAB3IL1 | Rab regulation of trafficking |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RAB3IP | RAB3IL1 | 1.0 | 0.949 | bioplex (RAB3IL1) bioplex_WMM boldt (RAB3IP) boldt_WMM |
| PPFIA3 | RAB3IL1 | 0.916 | 0.839 | bioplex (RAB3IL1) bioplex_WMM |
| PPFIA3 | RAB3IP | 0.008 | 0.082 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_06343 has an average edge precision of 0.623 which is ranked 1810 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| RAB3IP | HuMAP2_03605 HuMAP2_03962 HuMAP2_06343 |
| PPFIA3 | HuMAP2_00347 HuMAP2_03605 HuMAP2_03962 HuMAP2_05013 HuMAP2_05428 HuMAP2_06343 |
| RAB3IL1 | HuMAP2_03605 HuMAP2_03962 HuMAP2_05013 HuMAP2_05222 HuMAP2_06343 |