hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06345
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CEP57 | Centrosomal protein of 57 kDa (Cep57) (FGF2-interacting protein) (Testis-specific protein 57) (Translokin) | UniProt NCBI |
| TNFRSF8 | Tumor necrosis factor receptor superfamily member 8 (CD30L receptor) (Ki-1 antigen) (Lymphocyte activation antigen CD30) (CD antigen CD30) | UniProt NCBI |
| TRAF3 | TNF receptor-associated factor 3 (EC 2.3.2.27) (CAP-1) (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein 1) (LAP1) (RING-type E3 ubiquitin transferase TRAF3) | UniProt NCBI |
| CCDC112 | Coiled-coil domain-containing protein 112 (Mutated in bladder cancer protein 1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5668541 | 0.0356320611636 | 0.5 | TNFRSF8 TRAF3 | TNFR2 non-canonical NF-kB pathway |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CEP57 | TNFRSF8 | 0.119 | 0.393 | bioplex (TNFRSF8) bioplex_WMM |
| CCDC112 | TNFRSF8 | 0.046 | 0.294 | bioplex (TNFRSF8) bioplex_WMM |
| TRAF3 | TNFRSF8 | 0.031 | 0.24 | bioplex (TNFRSF8) bioplex_WMM |
| CCDC112 | TRAF3 | 0.009 | 0.099 | bioplex_WMM WMM_only |
| CCDC112 | CEP57 | 0.008 | 0.04 | bioplex_WMM WMM_only |
| TRAF3 | CEP57 | 0.007 | 0.01 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_06345 has an average edge precision of 0.179 which is ranked 6430 out of all 6965 complexes.
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