hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06349
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SKIV2L | Helicase SKI2W (Ski2) (EC 3.6.4.-) (Helicase-like protein) (HLP) | UniProt NCBI |
| OSBPL2 | Oxysterol-binding protein-related protein 2 (ORP-2) (OSBP-related protein 2) | UniProt NCBI |
| TTC37 | Tetratricopeptide repeat protein 37 (TPR repeat protein 37) (SKI3 homolog) (Ski3) (Tricho-hepatic-enteric syndrome protein) (Thespin) | UniProt NCBI |
| UNC45A | Protein unc-45 homolog A (Unc-45A) (GCUNC-45) (Smooth muscle cell-associated protein 1) (SMAP-1) | UniProt NCBI |
| FAM83H | Protein FAM83H | UniProt NCBI |
| SDF2 | Stromal cell-derived factor 2 (SDF-2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:1168 | 2.51655344529e-05 | 0.333333333333 | SKIV2L TTC37 | SKI complex |
| HP:0009886 | 0.00112625143517 | 0.333333333333 | SKIV2L TTC37 | Trichorrhexis nodosa |
| REAC:R-HSA-429958 | 0.00265393377546 | 0.333333333333 | SKIV2L TTC37 | mRNA decay by 3' to 5' exoribonuclease |
| HP:0040130 | 0.00412589193299 | 0.333333333333 | SKIV2L TTC37 | Abnormal serum iron concentration |
| HP:0011031 | 0.00495018352279 | 0.333333333333 | SKIV2L TTC37 | Abnormality of iron homeostasis |
| HP:0011472 | 0.0101912456166 | 0.333333333333 | SKIV2L TTC37 | Abnormality of small intestinal villus morphology |
| HP:0011473 | 0.0101912456166 | 0.333333333333 | SKIV2L TTC37 | Villous atrophy |
| HP:0011030 | 0.0114630974264 | 0.333333333333 | SKIV2L TTC37 | Abnormal blood transition element cation concentration |
| HP:0002224 | 0.0128094019441 | 0.333333333333 | SKIV2L TTC37 | Woolly hair |
| KEGG:03018 | 0.0176099294651 | 0.333333333333 | SKIV2L TTC37 | RNA degradation |
| GO:0055087 | 0.020283420769 | 0.333333333333 | SKIV2L TTC37 | Ski complex |
| HP:0003328 | 0.0262553193116 | 0.333333333333 | SKIV2L TTC37 | Abnormal hair laboratory examination |
| REAC:R-HSA-429914 | 0.0338154872995 | 0.333333333333 | SKIV2L TTC37 | Deadenylation-dependent mRNA decay |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SKIV2L | TTC37 | 1.0 | 0.949 | hein_WMM bioplex_WMM youn_WMM gupta_WMM fraction |
| SKIV2L | UNC45A | 0.281 | 0.487 | bioplex_WMM gupta_WMM fraction |
| UNC45A | TTC37 | 0.034 | 0.261 | bioplex_WMM gupta_WMM fraction boldt_WMM |
| UNC45A | FAM83H | 0.03 | 0.234 | bioplex (UNC45A) bioplex_WMM gupta_WMM |
| SKIV2L | OSBPL2 | 0.026 | 0.224 | fraction |
| UNC45A | SDF2 | 0.021 | 0.186 | bioplex_WMM boldt fraction boldt_WMM |
| FAM83H | SDF2 | 0.006 | 0.004 | bioplex_WMM WMM_only |
| SKIV2L | FAM83H | 0.006 | 0.008 | bioplex_WMM youn_WMM WMM_only |
| SDF2 | TTC37 | 0.006 | 0.011 | bioplex_WMM WMM_only |
| SKIV2L | SDF2 | 0.006 | 0.011 | bioplex_WMM WMM_only |
| OSBPL2 | TTC37 | 0.005 | 0.008 | bioplex_WMM fraction |
| FAM83H | TTC37 | 0.004 | 0.015 | bioplex_WMM youn_WMM WMM_only |
| UNC45A | OSBPL2 | 0.003 | 0.011 | gupta_WMM fraction |
Images
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Complex HuMAP2_06349 has an average edge precision of 0.185 which is ranked 6370 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| SKIV2L | HuMAP2_00385 HuMAP2_05230 HuMAP2_06349 HuMAP2_06992 |
| OSBPL2 | HuMAP2_00871 HuMAP2_03409 HuMAP2_06349 |
| TTC37 | HuMAP2_05230 HuMAP2_06349 HuMAP2_06992 |
| UNC45A | HuMAP2_00385 HuMAP2_05230 HuMAP2_06349 |
| FAM83H | HuMAP2_00673 HuMAP2_00796 HuMAP2_03772 HuMAP2_06349 |
| SDF2 | HuMAP2_01951 HuMAP2_02585 HuMAP2_04796 HuMAP2_06349 |