hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06350
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SKA3 | Spindle and kinetochore-associated protein 3 | UniProt NCBI |
| NOL4L | Nucleolar protein 4-like | UniProt NCBI |
| SKA2 | Spindle and kinetochore-associated protein 2 (Protein FAM33A) | UniProt NCBI |
| SKA1 | Spindle and kinetochore-associated protein 1 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0000940 | 0.000132158586819 | 0.75 | SKA2 SKA3 SKA1 | condensed chromosome outer kinetochore |
| GO:0000777 | 0.00147288799354 | 0.75 | SKA2 SKA3 SKA1 | condensed chromosome kinetochore |
| GO:0000779 | 0.00331394418715 | 0.75 | SKA2 SKA3 SKA1 | condensed chromosome, centromeric region |
| GO:0005876 | 0.0080085486554 | 0.75 | SKA2 SKA3 SKA1 | spindle microtubule |
| GO:0031110 | 0.0165706850483 | 0.75 | SKA2 SKA3 SKA1 | regulation of microtubule polymerization or depolymerization |
| REAC:R-HSA-141444 | 0.041754071825 | 0.5 | SKA2 SKA1 | Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal |
| REAC:R-HSA-141424 | 0.041754071825 | 0.5 | SKA2 SKA1 | Amplification of signal from the kinetochores |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SKA1 | SKA3 | 1.0 | 0.949 | hein_WMM bioplex (SKA3) bioplex_WMM youn_WMM hein (SKA1,SKA3) gupta_WMM |
| SKA2 | SKA3 | 1.0 | 0.949 | hein_WMM bioplex (SKA3) bioplex_WMM youn_WMM hein (SKA3) gupta_WMM |
| SKA1 | SKA2 | 0.874 | 0.806 | hein_WMM bioplex_WMM youn_WMM hein (SKA1) gupta_WMM |
| SKA3 | NOL4L | 0.318 | 0.509 | bioplex (SKA3) bioplex_WMM |
| SKA2 | NOL4L | 0.008 | 0.04 | bioplex_WMM WMM_only |
| SKA1 | NOL4L | 0.008 | 0.025 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_06350 has an average edge precision of 0.546 which is ranked 2220 out of all 6965 complexes.
Related Complexes