hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06354
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| NUSAP1 | Nucleolar and spindle-associated protein 1 (NuSAP) | UniProt NCBI |
| KPNA2 | Importin subunit alpha-1 (Karyopherin subunit alpha-2) (RAG cohort protein 1) (SRP1-alpha) | UniProt NCBI |
| IPO7 | Importin-7 (Imp7) (Ran-binding protein 7) (RanBP7) | UniProt NCBI |
| HNRNPUL2 | Heterogeneous nuclear ribonucleoprotein U-like protein 2 (Scaffold-attachment factor A2) (SAF-A2) | UniProt NCBI |
| KPNB1 | Importin subunit beta-1 (Importin-90) (Karyopherin subunit beta-1) (Nuclear factor p97) (Pore targeting complex 97 kDa subunit) (PTAC97) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6142 | 6.70868171695e-06 | 0.4 | KPNA2 KPNB1 | KPNA2-KPNB1 complex |
| REAC:R-HSA-168276 | 0.00894729002053 | 0.4 | KPNA2 KPNB1 | NS1 Mediated Effects on Host Pathways |
| REAC:R-HSA-168253 | 0.00944309181669 | 0.4 | KPNA2 KPNB1 | Host Interactions with Influenza Factors |
| REAC:R-HSA-1169408 | 0.0295837500362 | 0.4 | KPNA2 KPNB1 | ISG15 antiviral mechanism |
| REAC:R-HSA-1169410 | 0.0361060371214 | 0.4 | KPNA2 KPNB1 | Antiviral mechanism by IFN-stimulated genes |
| CORUM:6143 | 0.0499494897235 | 0.2 | KPNB1 | KPNB1-RAN complex |
| CORUM:7543 | 0.0499494897235 | 0.2 | KPNB1 | KPNB1-SMN-SPN complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| KPNB1 | IPO7 | 0.995 | 0.924 | hein_WMM bioplex_WMM boldt hein (KPNB1) fraction boldt_WMM treiber_WMM |
| KPNB1 | KPNA2 | 0.988 | 0.901 | hein_WMM bioplex (KPNA2) bioplex_WMM boldt hein (KPNB1) fraction boldt_WMM treiber_WMM |
| KPNB1 | NUSAP1 | 0.794 | 0.76 | hein_WMM bioplex (NUSAP1) bioplex_WMM hein (KPNB1) boldt_WMM |
| HNRNPUL2 | KPNB1 | 0.712 | 0.728 | bioplex_WMM fraction treiber_WMM |
| KPNA2 | IPO7 | 0.017 | 0.167 | hein_WMM bioplex (KPNA2) bioplex_WMM Guru boldt youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
| HNRNPUL2 | NUSAP1 | 0.006 | 0.005 | bioplex_WMM youn_WMM WMM_only |
| HNRNPUL2 | KPNA2 | 0.004 | 0.005 | bioplex_WMM youn_WMM gupta_WMM fraction treiber_WMM |
| HNRNPUL2 | IPO7 | 0.0 | 0.017 | bioplex_WMM youn_WMM gupta_WMM fraction treiber_WMM |
| NUSAP1 | IPO7 | 0.0 | 0.013 | hein_WMM bioplex (NUSAP1) bioplex_WMM youn_WMM gupta_WMM |
| NUSAP1 | KPNA2 | 0.0 | 0.008 | hein_WMM bioplex (KPNA2,NUSAP1) bioplex_WMM youn_WMM gupta_WMM fraction |
Images
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Complex HuMAP2_06354 has an average edge precision of 0.353 which is ranked 3901 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| NUSAP1 | HuMAP2_00798 HuMAP2_03992 HuMAP2_06097 HuMAP2_06354 |
| KPNA2 | HuMAP2_01285 HuMAP2_01705 HuMAP2_04098 HuMAP2_04747 HuMAP2_06354 |
| IPO7 | HuMAP2_04857 HuMAP2_06354 HuMAP2_06690 |
| HNRNPUL2 | HuMAP2_00798 HuMAP2_06354 |
| KPNB1 | HuMAP2_00798 HuMAP2_01285 HuMAP2_02831 HuMAP2_03992 HuMAP2_04028 HuMAP2_06354 |