hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06375
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RACK1 | Receptor of activated protein C kinase 1 (Cell proliferation-inducing gene 21 protein) (Guanine nucleotide-binding protein subunit beta-2-like 1) (Guanine nucleotide-binding protein subunit beta-like protein 12.3) (Human lung cancer oncogene 7 protein) (HLC-7) (Receptor for activated C kinase) (Small ribosomal subunit protein RACK1) [Cleaved into: Receptor of activated protein C kinase 1, N-terminally processed (Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed)] | UniProt NCBI |
| HELZ | Probable helicase with zinc finger domain (EC 3.6.4.-) (Down-regulated in human cancers protein) | UniProt NCBI |
| WIPI1 | WD repeat domain phosphoinositide-interacting protein 1 (WIPI-1) (Atg18 protein homolog) (WD40 repeat protein interacting with phosphoinositides of 49 kDa) (WIPI 49 kDa) | UniProt NCBI |
| CROT | Peroxisomal carnitine O-octanoyltransferase (COT) (EC 2.3.1.137) | UniProt NCBI |
| PCK1 | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] (PEPCK-C) (EC 4.1.1.32) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7011 | 0.0499494897235 | 0.2 | RACK1 | FERMT3-RACK1 complex |
| CORUM:7012 | 0.0499494897235 | 0.2 | RACK1 | ITGB1-RACK1 complex |
| CORUM:7013 | 0.0499494897235 | 0.2 | RACK1 | ITGB2-RACK1 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| WIPI1 | RACK1 | 0.838 | 0.783 | bioplex (WIPI1) bioplex_WMM |
| RACK1 | HELZ | 0.113 | 0.382 | bioplex (RACK1) bioplex_WMM gupta_WMM |
| PCK1 | RACK1 | 0.064 | 0.349 | fraction |
| RACK1 | CROT | 0.063 | 0.348 | bioplex (CROT) fraction |
Images
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Complex HuMAP2_06375 has an average edge precision of 0.466 which is ranked 2754 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| RACK1 | HuMAP2_04124 HuMAP2_05653 HuMAP2_06375 |
| HELZ | HuMAP2_04124 HuMAP2_04239 HuMAP2_06375 |
| WIPI1 | HuMAP2_04124 HuMAP2_05653 HuMAP2_06375 |
| CROT | HuMAP2_04641 HuMAP2_06063 HuMAP2_06375 |
| PCK1 | HuMAP2_00780 HuMAP2_02821 HuMAP2_03122 HuMAP2_04124 HuMAP2_06375 HuMAP2_06449 |