hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06380
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CERS2 | Ceramide synthase 2 (CerS2) (LAG1 longevity assurance homolog 2) (SP260) (Tumor metastasis-suppressor gene 1 protein) | UniProt NCBI |
| KDSR | 3-ketodihydrosphingosine reductase (KDS reductase) (EC 1.1.1.102) (3-dehydrosphinganine reductase) (Follicular variant translocation protein 1) (FVT-1) (Short chain dehydrogenase/reductase family 35C member 1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00600 | 0.000119635986191 | 1.0 | CERS2 KDSR | Sphingolipid metabolism |
| WP:WP1422 | 0.000121088932808 | 1.0 | CERS2 KDSR | Sphingolipid pathway |
| REAC:R-HSA-1660661 | 0.000940193062392 | 1.0 | CERS2 KDSR | Sphingolipid de novo biosynthesis |
| REAC:R-HSA-428157 | 0.00452666927187 | 1.0 | CERS2 KDSR | Sphingolipid metabolism |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| KDSR | CERS2 | 0.023 | 0.208 | bioplex_WMM boldt boldt_WMM |
Images
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Complex HuMAP2_06380 has an average edge precision of 0.208 which is ranked 6059 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| CERS2 | HuMAP2_01266 HuMAP2_01787 HuMAP2_03970 HuMAP2_06380 |
| KDSR | HuMAP2_01092 HuMAP2_03970 HuMAP2_06380 HuMAP2_06974 |