hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06389
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| MRPL46 | 39S ribosomal protein L46, mitochondrial (L46mt) (MRP-L46) (Mitochondrial large ribosomal subunit protein mL46) (P2ECSL) | UniProt NCBI |
| MRPL40 | 39S ribosomal protein L40, mitochondrial (L40mt) (MRP-L40) (Mitochondrial large ribosomal subunit protein mL40) (Nuclear localization signal-containing protein deleted in velocardiofacial syndrome) (Up-regulated in metastasis) | UniProt NCBI |
| MRPL48 | 39S ribosomal protein L48, mitochondrial (L48mt) (MRP-L48) (Mitochondrial large ribosomal subunit protein mL48) | UniProt NCBI |
| MRPL55 | 39S ribosomal protein L55, mitochondrial (L55mt) (MRP-L55) (Mitochondrial large ribosomal subunit protein bL31m) (Mitochondrial large ribosomal subunit protein mL55) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:324 | 8.08794479656e-09 | 1.0 | MRPL55 MRPL48 MRPL46 MRPL40 | 39S ribosomal subunit, mitochondrial |
| CORUM:320 | 6.13641325067e-08 | 1.0 | MRPL55 MRPL48 MRPL46 MRPL40 | 55S ribosome, mitochondrial |
| REAC:R-HSA-5419276 | 2.01866015002e-07 | 1.0 | MRPL55 MRPL48 MRPL46 MRPL40 | Mitochondrial translation termination |
| REAC:R-HSA-5368286 | 2.01866015002e-07 | 1.0 | MRPL55 MRPL48 MRPL46 MRPL40 | Mitochondrial translation initiation |
| REAC:R-HSA-5389840 | 2.01866015002e-07 | 1.0 | MRPL55 MRPL48 MRPL46 MRPL40 | Mitochondrial translation elongation |
| REAC:R-HSA-5368287 | 2.64790239123e-07 | 1.0 | MRPL55 MRPL48 MRPL46 MRPL40 | Mitochondrial translation |
| GO:0000315 | 8.96024572897e-06 | 1.0 | MRPL55 MRPL48 MRPL46 MRPL40 | organellar large ribosomal subunit |
| GO:0005762 | 8.96024572897e-06 | 1.0 | MRPL55 MRPL48 MRPL46 MRPL40 | mitochondrial large ribosomal subunit |
| REAC:R-HSA-72766 | 2.61768581314e-05 | 1.0 | MRPL55 MRPL48 MRPL46 MRPL40 | Translation |
| GO:0000313 | 4.93957666921e-05 | 1.0 | MRPL55 MRPL48 MRPL46 MRPL40 | organellar ribosome |
| GO:0005761 | 4.93957666921e-05 | 1.0 | MRPL55 MRPL48 MRPL46 MRPL40 | mitochondrial ribosome |
| GO:0070125 | 5.43019580356e-05 | 1.0 | MRPL55 MRPL48 MRPL46 MRPL40 | mitochondrial translational elongation |
| GO:0070126 | 5.68877655611e-05 | 1.0 | MRPL55 MRPL48 MRPL46 MRPL40 | mitochondrial translational termination |
| GO:0006415 | 9.56604850625e-05 | 1.0 | MRPL55 MRPL48 MRPL46 MRPL40 | translational termination |
| GO:0015934 | 0.000135718631087 | 1.0 | MRPL55 MRPL48 MRPL46 MRPL40 | large ribosomal subunit |
| GO:0006414 | 0.000200399046415 | 1.0 | MRPL55 MRPL48 MRPL46 MRPL40 | translational elongation |
| GO:0032543 | 0.000303906363787 | 1.0 | MRPL55 MRPL48 MRPL46 MRPL40 | mitochondrial translation |
| GO:0140053 | 0.000625429030777 | 1.0 | MRPL55 MRPL48 MRPL46 MRPL40 | mitochondrial gene expression |
| GO:0044391 | 0.00100892420578 | 1.0 | MRPL55 MRPL48 MRPL46 MRPL40 | ribosomal subunit |
| GO:0043624 | 0.00100892420578 | 1.0 | MRPL55 MRPL48 MRPL46 MRPL40 | cellular protein complex disassembly |
| GO:0005840 | 0.00164259339851 | 1.0 | MRPL55 MRPL48 MRPL46 MRPL40 | ribosome |
| GO:0098798 | 0.00297010167954 | 1.0 | MRPL55 MRPL48 MRPL46 MRPL40 | mitochondrial protein complex |
| GO:0032984 | 0.00620315916282 | 1.0 | MRPL55 MRPL48 MRPL46 MRPL40 | protein-containing complex disassembly |
| GO:0005743 | 0.0166033324327 | 1.0 | MRPL55 MRPL48 MRPL46 MRPL40 | mitochondrial inner membrane |
| HPA:056010_03 | 0.019302446397 | 0.75 | MRPL55 MRPL46 MRPL40 | tonsil; germinal center cells[Uncertain,High] |
| HPA:021010_03 | 0.0218446946143 | 0.75 | MRPL55 MRPL46 MRPL40 | heart muscle; myocytes[Uncertain,High] |
| GO:0019866 | 0.0226824675867 | 1.0 | MRPL55 MRPL48 MRPL46 MRPL40 | organelle inner membrane |
| HPA:056020_03 | 0.0244560243519 | 0.75 | MRPL55 MRPL46 MRPL40 | tonsil; non-germinal center cells[Uncertain,High] |
| GO:0005759 | 0.0280287343891 | 1.0 | MRPL55 MRPL48 MRPL46 MRPL40 | mitochondrial matrix |
| HPA:013020_03 | 0.0307757765426 | 0.75 | MRPL55 MRPL46 MRPL40 | endometrium 1; glandular cells[Uncertain,High] |
| HPA:040010_03 | 0.031444391961 | 0.75 | MRPL55 MRPL46 MRPL40 | seminal vesicle; glandular cells[Uncertain,High] |
| GO:0022411 | 0.0393249836577 | 1.0 | MRPL55 MRPL48 MRPL46 MRPL40 | cellular component disassembly |
| REAC:R-HSA-392499 | 0.0403329683602 | 1.0 | MRPL55 MRPL48 MRPL46 MRPL40 | Metabolism of proteins |
| HPA:039010_03 | 0.0416307958449 | 0.75 | MRPL55 MRPL46 MRPL40 | salivary gland; glandular cells[Uncertain,High] |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| MRPL40 | MRPL46 | 1.0 | 0.949 | hein_WMM bioplex (MRPL46) bioplex_WMM Guru youn_WMM fraction treiber_WMM |
| MRPL48 | MRPL46 | 1.0 | 0.949 | hein_WMM bioplex (MRPL46) bioplex_WMM Guru youn_WMM fraction treiber_WMM |
| MRPL55 | MRPL46 | 1.0 | 0.949 | hein_WMM bioplex (MRPL46) bioplex_WMM Guru youn_WMM fraction |
| MRPL40 | MRPL55 | 0.999 | 0.949 | hein_WMM bioplex_WMM Guru youn_WMM fraction |
| MRPL40 | MRPL48 | 0.933 | 0.848 | hein_WMM bioplex_WMM Guru youn_WMM fraction treiber_WMM |
| MRPL48 | MRPL55 | 0.859 | 0.796 | hein_WMM bioplex_WMM Guru youn_WMM fraction |
Images
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Complex HuMAP2_06389 has an average edge precision of 0.907 which is ranked 528 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| MRPL46 | HuMAP2_01036 HuMAP2_04440 HuMAP2_04542 HuMAP2_06389 HuMAP2_06482 HuMAP2_06691 |
| MRPL40 | HuMAP2_01036 HuMAP2_04440 HuMAP2_04542 HuMAP2_06389 HuMAP2_06482 HuMAP2_06691 |
| MRPL48 | HuMAP2_01036 HuMAP2_04542 HuMAP2_06389 HuMAP2_06482 HuMAP2_06691 |
| MRPL55 | HuMAP2_01036 HuMAP2_04542 HuMAP2_06389 HuMAP2_06482 HuMAP2_06691 |