hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06399
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| FUS | RNA-binding protein FUS (75 kDa DNA-pairing protein) (Oncogene FUS) (Oncogene TLS) (POMp75) (Translocated in liposarcoma protein) | UniProt NCBI |
| HNRNPR | Heterogeneous nuclear ribonucleoprotein R (hnRNP R) | UniProt NCBI |
| ZFR | Zinc finger RNA-binding protein (hZFR) (M-phase phosphoprotein homolog) | UniProt NCBI |
| DDX17 | Probable ATP-dependent RNA helicase DDX17 (EC 3.6.4.13) (DEAD box protein 17) (DEAD box protein p72) (DEAD box protein p82) (RNA-dependent helicase p72) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:3082 | 1.11368231542e-07 | 0.75 | FUS DDX17 HNRNPR | DGCR8 multiprotein complex |
| CORUM:1332 | 0.000953737505851 | 0.5 | FUS DDX17 | Large Drosha complex |
| WP:WP411 | 0.0128777248997 | 0.5 | FUS HNRNPR | mRNA Processing |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ZFR | HNRNPR | 0.998 | 0.936 | bioplex (HNRNPR) bioplex_WMM Guru youn_WMM gupta_WMM fraction treiber_WMM |
| FUS | HNRNPR | 0.988 | 0.901 | hein_WMM bioplex (FUS,HNRNPR) bioplex_WMM youn_WMM hein (FUS) gupta_WMM fraction treiber_WMM |
| DDX17 | HNRNPR | 0.932 | 0.846 | hein_WMM bioplex_WMM Guru fraction treiber_WMM |
| ZFR | DDX17 | 0.0 | 0.011 | bioplex_WMM Guru fraction treiber_WMM |
| DDX17 | FUS | 0.0 | 0.008 | hein_WMM bioplex (DDX17,FUS) bioplex_WMM hein (FUS) fraction treiber_WMM |
| ZFR | FUS | 0.0 | 0.0 | bioplex_WMM youn_WMM gupta_WMM fraction treiber_WMM |
Images
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Complex HuMAP2_06399 has an average edge precision of 0.45 which is ranked 2870 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| FUS | HuMAP2_04525 HuMAP2_06399 |
| HNRNPR | HuMAP2_04525 HuMAP2_06399 HuMAP2_06411 |
| ZFR | HuMAP2_00340 HuMAP2_01587 HuMAP2_02239 HuMAP2_02717 HuMAP2_04525 HuMAP2_05966 HuMAP2_06399 HuMAP2_06996 |
| DDX17 | HuMAP2_00707 HuMAP2_04312 HuMAP2_04605 HuMAP2_06399 |