hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06403
Confidence: Extremely High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| NSL1 | Kinetochore-associated protein NSL1 homolog | UniProt NCBI |
| DSN1 | Kinetochore-associated protein DSN1 homolog | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:1464 | 2.51388519356e-05 | 1.0 | NSL1 DSN1 | Mis12 centromere complex |
| GO:0000444 | 0.00270494046827 | 1.0 | NSL1 DSN1 | MIS12/MIND type complex |
| REAC:R-HSA-141444 | 0.0070154156135 | 1.0 | NSL1 DSN1 | Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal |
| REAC:R-HSA-141424 | 0.0070154156135 | 1.0 | NSL1 DSN1 | Amplification of signal from the kinetochores |
| REAC:R-HSA-69618 | 0.00950416195513 | 1.0 | NSL1 DSN1 | Mitotic Spindle Checkpoint |
| REAC:R-HSA-2500257 | 0.0119660935214 | 1.0 | NSL1 DSN1 | Resolution of Sister Chromatid Cohesion |
| REAC:R-HSA-5663220 | 0.0147112561527 | 1.0 | NSL1 DSN1 | RHO GTPases Activate Formins |
| REAC:R-HSA-2467813 | 0.0279091534189 | 1.0 | NSL1 DSN1 | Separation of Sister Chromatids |
| REAC:R-HSA-68882 | 0.0304096312248 | 1.0 | NSL1 DSN1 | Mitotic Anaphase |
| REAC:R-HSA-68877 | 0.0304096312248 | 1.0 | NSL1 DSN1 | Mitotic Prometaphase |
| REAC:R-HSA-2555396 | 0.0307297326061 | 1.0 | NSL1 DSN1 | Mitotic Metaphase and Anaphase |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| DSN1 | NSL1 | 1.0 | 0.949 | hein_WMM bioplex (DSN1,NSL1) bioplex_WMM hein (DSN1) |
Images
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Complex HuMAP2_06403 has an average edge precision of 0.949 which is ranked 5 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| NSL1 | HuMAP2_01723 HuMAP2_06403 HuMAP2_06889 |
| DSN1 | HuMAP2_01723 HuMAP2_06403 HuMAP2_06889 |