hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06411
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| DHX36 | ATP-dependent DNA/RNA helicase DHX36 (EC 3.6.4.12) (EC 3.6.4.13) (DEAD/H box polypeptide 36) (DEAH-box protein 36) (G4-resolvase-1) (G4R1) (MLE-like protein 1) (RNA helicase associated with AU-rich element protein) | UniProt NCBI |
| DNMT1 | DNA (cytosine-5)-methyltransferase 1 (Dnmt1) (EC 2.1.1.37) (CXXC-type zinc finger protein 9) (DNA methyltransferase HsaI) (DNA MTase HsaI) (M.HsaI) (MCMT) | UniProt NCBI |
| RBMX | RNA-binding motif protein, X chromosome (Glycoprotein p43) (Heterogeneous nuclear ribonucleoprotein G) (hnRNP G) [Cleaved into: RNA-binding motif protein, X chromosome, N-terminally processed] | UniProt NCBI |
| OTUD6A | OTU domain-containing protein 6A (EC 3.4.19.12) (DUBA-2) | UniProt NCBI |
| ZNF326 | DBIRD complex subunit ZNF326 (Zinc finger protein 326) (Zinc finger protein interacting with mRNPs and DBC1) | UniProt NCBI |
| STRBP | Spermatid perinuclear RNA-binding protein | UniProt NCBI |
| HNRNPR | Heterogeneous nuclear ribonucleoprotein R (hnRNP R) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| MIRNA:hsa-miR-5096 | 0.000869277660396 | 0.571428571429 | STRBP HNRNPR OTUD6A ZNF326 | hsa-miR-5096 |
| CORUM:1181 | 0.0297343384587 | 0.285714285714 | HNRNPR RBMX | C complex spliceosome |
| CORUM:862 | 0.0499886427319 | 0.142857142857 | DNMT1 | DNMT1-EHMT2 complex |
| CORUM:6336 | 0.0499886427319 | 0.142857142857 | DNMT1 | CTNNB1-DNMT1 complex |
| CORUM:6847 | 0.0499886427319 | 0.142857142857 | ZNF326 | DBIRD complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| STRBP | HNRNPR | 0.063 | 0.346 | bioplex (HNRNPR,STRBP) bioplex_WMM youn_WMM gupta_WMM treiber_WMM |
| HNRNPR | DHX36 | 0.061 | 0.335 | bioplex_WMM youn_WMM gupta_WMM fraction treiber_WMM |
| OTUD6A | HNRNPR | 0.053 | 0.301 | fraction |
| DNMT1 | HNRNPR | 0.052 | 0.301 | bioplex_WMM youn_WMM gupta_WMM fraction |
| RBMX | HNRNPR | 0.037 | 0.265 | hein_WMM bioplex (HNRNPR,RBMX) bioplex_WMM youn_WMM gupta_WMM fraction treiber_WMM |
| RBMX | ZNF326 | 0.028 | 0.23 | hein_WMM bioplex (RBMX) bioplex_WMM youn_WMM gupta_WMM treiber_WMM |
| ZNF326 | HNRNPR | 0.023 | 0.209 | hein_WMM bioplex (HNRNPR) bioplex_WMM youn_WMM gupta_WMM treiber_WMM |
| STRBP | ZNF326 | 0.01 | 0.115 | bioplex (STRBP) bioplex_WMM youn_WMM gupta_WMM treiber_WMM |
| RBMX | STRBP | 0.008 | 0.054 | bioplex (STRBP) bioplex_WMM youn_WMM gupta_WMM treiber_WMM |
| STRBP | DHX36 | 0.007 | 0.006 | bioplex_WMM youn_WMM WMM_only treiber_WMM |
| DNMT1 | OTUD6A | 0.007 | 0.004 | bioplex_WMM WMM_only |
| DNMT1 | DHX36 | 0.007 | 0.003 | bioplex_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
| ZNF326 | DHX36 | 0.007 | 0.006 | bioplex_WMM youn_WMM WMM_only treiber_WMM |
| DNMT1 | STRBP | 0.007 | 0.002 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| DNMT1 | ZNF326 | 0.006 | 0.002 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| DNMT1 | RBMX | 0.003 | 0.018 | bioplex_WMM youn_WMM gupta_WMM fraction |
| RBMX | DHX36 | 0.0 | 0.001 | bioplex (RBMX) bioplex_WMM youn_WMM gupta_WMM fraction |
Images
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Complex HuMAP2_06411 has an average edge precision of 0.129 which is ranked 6832 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| DHX36 | HuMAP2_05099 HuMAP2_06411 |
| DNMT1 | HuMAP2_01019 HuMAP2_02434 HuMAP2_06314 HuMAP2_06411 |
| RBMX | HuMAP2_01393 HuMAP2_02261 HuMAP2_03721 HuMAP2_04343 HuMAP2_05678 HuMAP2_06411 |
| OTUD6A | HuMAP2_02126 HuMAP2_04071 HuMAP2_06121 HuMAP2_06411 |
| ZNF326 | HuMAP2_02342 HuMAP2_02606 HuMAP2_04343 HuMAP2_06411 |
| STRBP | HuMAP2_01587 HuMAP2_02857 HuMAP2_03452 HuMAP2_04131 HuMAP2_05966 HuMAP2_06411 |
| HNRNPR | HuMAP2_04525 HuMAP2_06399 HuMAP2_06411 |