hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06420
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| UTP4 | U3 small nucleolar RNA-associated protein 4 homolog (Cirhin) (UTP4 small subunit processome component) | UniProt NCBI |
| NOL7 | Nucleolar protein 7 (Nucleolar protein of 27 kDa) | UniProt NCBI |
| WDR75 | WD repeat-containing protein 75 (U3 small nucleolar RNA-associated protein 17 homolog) | UniProt NCBI |
| CNRIP1 | CB1 cannabinoid receptor-interacting protein 1 (CRIP-1) | UniProt NCBI |
| NOL11 | Nucleolar protein 11 | UniProt NCBI |
| UTP15 | U3 small nucleolar RNA-associated protein 15 homolog | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-6790901 | 5.81540421648e-07 | 0.666666666667 | UTP15 NOL11 WDR75 UTP4 | rRNA modification in the nucleus and cytosol |
| REAC:R-HSA-6791226 | 5.09116254048e-05 | 0.666666666667 | UTP15 NOL11 WDR75 UTP4 | Major pathway of rRNA processing in the nucleolus and cytosol |
| REAC:R-HSA-8868773 | 6.31725452927e-05 | 0.666666666667 | UTP15 NOL11 WDR75 UTP4 | rRNA processing in the nucleus and cytosol |
| REAC:R-HSA-72312 | 7.75166031651e-05 | 0.666666666667 | UTP15 NOL11 WDR75 UTP4 | rRNA processing |
| KEGG:03008 | 0.000121655342604 | 0.5 | UTP15 WDR75 UTP4 | Ribosome biogenesis in eukaryotes |
| GO:0045943 | 0.00240920978697 | 0.5 | UTP15 WDR75 NOL11 | positive regulation of transcription by RNA polymerase I |
| GO:0006356 | 0.00661098268806 | 0.5 | UTP15 WDR75 NOL11 | regulation of transcription by RNA polymerase I |
| REAC:R-HSA-8953854 | 0.00833913786065 | 0.666666666667 | UTP15 NOL11 WDR75 UTP4 | Metabolism of RNA |
| GO:0006364 | 0.0129505725968 | 0.666666666667 | UTP15 NOL11 WDR75 UTP4 | rRNA processing |
| GO:0016072 | 0.015875268856 | 0.666666666667 | UTP15 NOL11 WDR75 UTP4 | rRNA metabolic process |
| GO:0034455 | 0.020283420769 | 0.333333333333 | UTP4 NOL11 | t-UTP complex |
| GO:0042254 | 0.0442052130199 | 0.666666666667 | UTP15 NOL11 WDR75 UTP4 | ribosome biogenesis |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| UTP4 | NOL11 | 0.916 | 0.839 | bioplex (UTP4) bioplex_WMM youn_WMM gupta_WMM treiber_WMM |
| UTP4 | CNRIP1 | 0.648 | 0.686 | bioplex (CNRIP1) bioplex_WMM |
| UTP15 | UTP4 | 0.57 | 0.656 | hein_WMM bioplex (UTP4) bioplex_WMM youn_WMM gupta_WMM treiber_WMM |
| UTP15 | NOL11 | 0.428 | 0.576 | bioplex_WMM youn_WMM Malo gupta_WMM fraction treiber_WMM |
| UTP4 | WDR75 | 0.398 | 0.559 | bioplex (UTP4) bioplex_WMM youn_WMM gupta_WMM treiber_WMM |
| UTP15 | NOL7 | 0.06 | 0.336 | bioplex (NOL7) bioplex_WMM youn_WMM treiber_WMM |
| WDR75 | NOL7 | 0.048 | 0.295 | bioplex (NOL7) bioplex_WMM youn_WMM |
| UTP15 | WDR75 | 0.013 | 0.151 | bioplex_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
| WDR75 | NOL11 | 0.009 | 0.101 | bioplex_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
| NOL7 | NOL11 | 0.008 | 0.068 | bioplex (NOL7) bioplex_WMM youn_WMM |
| NOL7 | CNRIP1 | 0.007 | 0.005 | bioplex_WMM WMM_only |
| UTP4 | NOL7 | 0.006 | 0.004 | bioplex (NOL7,UTP4) bioplex_WMM youn_WMM treiber_WMM |
Images
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Complex HuMAP2_06420 has an average edge precision of 0.356 which is ranked 3818 out of all 6965 complexes.
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