hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06429
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| KCNC4 | Potassium voltage-gated channel subfamily C member 4 (KSHIIIC) (Voltage-gated potassium channel subunit Kv3.4) | UniProt NCBI |
| DCAF4L2 | DDB1- and CUL4-associated factor 4-like protein 2 (WD repeat-containing protein 21C) | UniProt NCBI |
| KCNC1 | Potassium voltage-gated channel subfamily C member 1 (NGK2) (Voltage-gated potassium channel subunit Kv3.1) (Voltage-gated potassium channel subunit Kv4) | UniProt NCBI |
| KCNC3 | Potassium voltage-gated channel subfamily C member 3 (KSHIIID) (Voltage-gated potassium channel subunit Kv3.3) | UniProt NCBI |
| RNF215 | RING finger protein 215 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-1296072 | 1.77393158174e-05 | 0.6 | KCNC1 KCNC3 KCNC4 | Voltage gated Potassium channels |
| REAC:R-HSA-1296071 | 0.000167928044622 | 0.6 | KCNC1 KCNC3 KCNC4 | Potassium Channels |
| GO:0032809 | 0.000507918241599 | 0.6 | KCNC1 KCNC3 KCNC4 | neuronal cell body membrane |
| GO:0044298 | 0.000507918241599 | 0.6 | KCNC1 KCNC3 KCNC4 | cell body membrane |
| GO:0032590 | 0.000739960245213 | 0.6 | KCNC1 KCNC3 KCNC4 | dendrite membrane |
| GO:0005251 | 0.00120569794977 | 0.6 | KCNC1 KCNC3 KCNC4 | delayed rectifier potassium channel activity |
| GO:0032589 | 0.00208420080219 | 0.6 | KCNC1 KCNC3 KCNC4 | neuron projection membrane |
| REAC:R-HSA-112316 | 0.0172109299174 | 0.6 | KCNC1 KCNC3 KCNC4 | Neuronal System |
| GO:0005249 | 0.022411068229 | 0.6 | KCNC1 KCNC3 KCNC4 | voltage-gated potassium channel activity |
| GO:0008076 | 0.034143769383 | 0.6 | KCNC1 KCNC3 KCNC4 | voltage-gated potassium channel complex |
| GO:0034705 | 0.0493791608738 | 0.6 | KCNC1 KCNC3 KCNC4 | potassium channel complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| KCNC3 | KCNC4 | 1.0 | 0.949 | bioplex (KCNC4) bioplex_WMM |
| KCNC1 | KCNC4 | 1.0 | 0.949 | bioplex (KCNC4) bioplex_WMM |
| KCNC4 | DCAF4L2 | 0.316 | 0.51 | bioplex (KCNC4) bioplex_WMM |
| KCNC4 | RNF215 | 0.088 | 0.352 | bioplex (KCNC4) bioplex_WMM |
| KCNC1 | RNF215 | 0.009 | 0.095 | bioplex_WMM WMM_only |
| KCNC3 | RNF215 | 0.009 | 0.095 | bioplex_WMM WMM_only |
| KCNC1 | KCNC3 | 0.009 | 0.095 | bioplex_WMM WMM_only |
| KCNC3 | DCAF4L2 | 0.008 | 0.091 | bioplex_WMM WMM_only |
| RNF215 | DCAF4L2 | 0.008 | 0.091 | bioplex_WMM WMM_only |
| KCNC1 | DCAF4L2 | 0.008 | 0.091 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_06429 has an average edge precision of 0.332 which is ranked 4215 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| KCNC4 | HuMAP2_00584 HuMAP2_02000 HuMAP2_02901 HuMAP2_03027 HuMAP2_06429 |
| DCAF4L2 | HuMAP2_03027 HuMAP2_03701 HuMAP2_06429 |
| KCNC1 | HuMAP2_00584 HuMAP2_02901 HuMAP2_03027 HuMAP2_06429 |
| KCNC3 | HuMAP2_00584 HuMAP2_02000 HuMAP2_02901 HuMAP2_03027 HuMAP2_06429 |
| RNF215 | HuMAP2_02901 HuMAP2_03027 HuMAP2_06429 |