hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06437
Confidence: Extremely High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| EEF1A1 | Elongation factor 1-alpha 1 (EF-1-alpha-1) (Elongation factor Tu) (EF-Tu) (Eukaryotic elongation factor 1 A-1) (eEF1A-1) (Leukocyte receptor cluster member 7) | UniProt NCBI |
| EEF1B2 | Elongation factor 1-beta (EF-1-beta) | UniProt NCBI |
| VARS | Valine--tRNA ligase (EC 6.1.1.9) (Protein G7a) (Valyl-tRNA synthetase) (ValRS) | UniProt NCBI |
| EEF1G | Elongation factor 1-gamma (EF-1-gamma) (eEF-1B gamma) | UniProt NCBI |
| EEF1D | Elongation factor 1-delta (EF-1-delta) (Antigen NY-CO-4) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP107 | 2.07570829481e-08 | 0.8 | EEF1A1 EEF1D EEF1B2 EEF1G | Translation Factors |
| REAC:R-HSA-72766 | 4.0494371971e-07 | 1.0 | EEF1D EEF1A1 EEF1G EEF1B2 VARS | Translation |
| GO:0005853 | 9.08185760231e-07 | 0.6 | EEF1A1 EEF1B2 EEF1D | eukaryotic translation elongation factor 1 complex |
| REAC:R-HSA-156842 | 1.01560921166e-06 | 0.8 | EEF1A1 EEF1D EEF1B2 EEF1G | Eukaryotic Translation Elongation |
| CORUM:1335 | 0.000910544014226 | 0.4 | EEF1A1 EEF1G | SNW1 complex |
| GO:0006414 | 0.000995750426332 | 0.8 | EEF1A1 EEF1D EEF1B2 EEF1G | translational elongation |
| GO:0006412 | 0.00235530637857 | 1.0 | EEF1D EEF1A1 EEF1G EEF1B2 VARS | translation |
| GO:0043043 | 0.00293652212837 | 1.0 | EEF1D EEF1A1 EEF1G EEF1B2 VARS | peptide biosynthetic process |
| REAC:R-HSA-392499 | 0.0039377533293 | 1.0 | EEF1D EEF1A1 EEF1G EEF1B2 VARS | Metabolism of proteins |
| KEGG:05134 | 0.00441762805526 | 0.4 | EEF1A1 EEF1G | Legionellosis |
| GO:0043604 | 0.00727283691478 | 1.0 | EEF1D EEF1A1 EEF1G EEF1B2 VARS | amide biosynthetic process |
| GO:0006518 | 0.00744517222081 | 1.0 | EEF1D EEF1A1 EEF1G EEF1B2 VARS | peptide metabolic process |
| HPA:009020_13 | 0.0136400669622 | 0.6 | EEF1A1 EEF1B2 EEF1D | cervix, uterine; squamous epithelial cells[Supported,High] |
| HPA:014020_13 | 0.0138986902566 | 0.6 | EEF1A1 EEF1B2 EEF1D | endometrium 2; glandular cells[Supported,High] |
| MIRNA:hsa-miR-93-3p | 0.0142310277096 | 0.6 | EEF1A1 VARS EEF1D | hsa-miR-93-3p |
| HPA:058010_13 | 0.0151025190567 | 0.6 | EEF1A1 EEF1B2 EEF1D | vagina; squamous epithelial cells[Supported,High] |
| HPA:040010_13 | 0.0165184888819 | 0.6 | EEF1A1 EEF1B2 EEF1D | seminal vesicle; glandular cells[Supported,High] |
| HPA:013020_13 | 0.0180192386998 | 0.6 | EEF1A1 EEF1B2 EEF1D | endometrium 1; glandular cells[Supported,High] |
| HPA:044010_13 | 0.0234185559543 | 0.6 | EEF1A1 EEF1B2 EEF1D | skin 2; epidermal cells[Supported,High] |
| HPA:039010_13 | 0.0236024900229 | 0.6 | EEF1A1 EEF1B2 EEF1D | salivary gland; glandular cells[Supported,High] |
| GO:0043603 | 0.0273795782463 | 1.0 | EEF1D EEF1A1 EEF1G EEF1B2 VARS | cellular amide metabolic process |
| HPA:016010_13 | 0.0293581469203 | 0.6 | EEF1A1 EEF1B2 EEF1D | esophagus; squamous epithelial cells[Supported,High] |
| HPA:009020_03 | 0.0397374089383 | 0.6 | EEF1A1 EEF1B2 EEF1D | cervix, uterine; squamous epithelial cells[Uncertain,High] |
| HPA:014010_12 | 0.0432077883482 | 0.6 | EEF1A1 EEF1B2 EEF1D | endometrium 2; cells in endometrial stroma[Supported,Medium] |
| HPA:057010_13 | 0.0437586981176 | 0.6 | EEF1A1 EEF1B2 EEF1D | urinary bladder; urothelial cells[Supported,High] |
| HPA:018010_13 | 0.0486283293616 | 0.6 | EEF1A1 EEF1B2 EEF1D | fallopian tube; glandular cells[Supported,High] |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| VARS | EEF1A1 | 1.0 | 0.949 | hein_WMM bioplex (EEF1A1) bioplex_WMM hein (EEF1A1) Malo fraction boldt_WMM treiber_WMM |
| EEF1A1 | EEF1G | 1.0 | 0.949 | hein_WMM bioplex (EEF1A1,EEF1G) bioplex_WMM Guru boldt hein (EEF1A1) Malo fraction boldt_WMM treiber_WMM |
| EEF1A1 | EEF1D | 1.0 | 0.949 | hein_WMM bioplex (EEF1A1,EEF1D) bioplex_WMM boldt hein (EEF1A1) Malo fraction boldt_WMM treiber_WMM |
| VARS | EEF1G | 1.0 | 0.949 | hein_WMM bioplex (EEF1G) bioplex_WMM Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| EEF1D | EEF1G | 1.0 | 0.949 | hein_WMM bioplex (EEF1D,EEF1G) bioplex_WMM boldt youn_WMM Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| EEF1B2 | EEF1A1 | 1.0 | 0.949 | hein_WMM bioplex (EEF1A1) bioplex_WMM Guru boldt hein (EEF1A1) Malo fraction boldt_WMM treiber_WMM |
| VARS | EEF1D | 1.0 | 0.949 | hein_WMM bioplex (EEF1D) bioplex_WMM Malo gupta_WMM fraction boldt_WMM |
| EEF1B2 | VARS | 1.0 | 0.949 | hein_WMM bioplex_WMM Malo gupta_WMM fraction boldt_WMM |
| EEF1B2 | EEF1D | 1.0 | 0.949 | hein_WMM bioplex (EEF1D) bioplex_WMM boldt youn_WMM Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| EEF1B2 | EEF1G | 1.0 | 0.949 | hein_WMM bioplex (EEF1G) bioplex_WMM boldt youn_WMM Malo gupta_WMM fraction boldt_WMM treiber_WMM |
Images
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Complex HuMAP2_06437 has an average edge precision of 0.949 which is ranked 2 out of all 6965 complexes.
Related Complexes