hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_06474
Confidence: Extremely High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| WASHC2A | WASH complex subunit 2A | UniProt NCBI |
| CAPZB | F-actin-capping protein subunit beta (CapZ beta) | UniProt NCBI |
| CAPZA2 | F-actin-capping protein subunit alpha-2 (CapZ alpha-2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04144 | 6.09806140287e-05 | 1.0 | CAPZB WASHC2A CAPZA2 | Endocytosis |
| CORUM:6671 | 0.000305232445119 | 0.666666666667 | CAPZB WASHC2A | PI4K2A-WASH complex |
| REAC:R-HSA-6811436 | 0.00818423736949 | 0.666666666667 | CAPZB CAPZA2 | COPI-independent Golgi-to-ER retrograde traffic |
| REAC:R-HSA-3371497 | 0.008858224502 | 0.666666666667 | CAPZB CAPZA2 | HSP90 chaperone cycle for steroid hormone receptors (SHR) |
| REAC:R-HSA-6807878 | 0.03104119222 | 0.666666666667 | CAPZB CAPZA2 | COPI-mediated anterograde transport |
| GO:0008290 | 0.0378589948753 | 0.666666666667 | CAPZB CAPZA2 | F-actin capping protein complex |
| REAC:R-HSA-2132295 | 0.0444303896492 | 0.666666666667 | CAPZB CAPZA2 | MHC class II antigen presentation |
| CORUM:6483 | 0.0499776345577 | 0.333333333333 | CAPZB | CAPZalpha-CAPZbeta complex |
| CORUM:7002 | 0.0499776345577 | 0.333333333333 | CAPZB | CAPZA3-CAPZB complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CAPZB | CAPZA2 | 1.0 | 0.949 | hein_WMM bioplex (CAPZA2) bioplex_WMM Guru boldt youn_WMM hein (CAPZA2) Malo gupta_WMM fraction boldt_WMM |
| CAPZA2 | WASHC2A | 1.0 | 0.949 | hein_WMM bioplex (CAPZA2) bioplex_WMM youn_WMM hein (CAPZA2) gupta_WMM |
| CAPZB | WASHC2A | 0.008 | 0.09 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only boldt_WMM |
Images
Click to enlarge
Complex HuMAP2_06474 has an average edge precision of 0.663 which is ranked 1577 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| WASHC2A | HuMAP2_02312 HuMAP2_03866 HuMAP2_03911 HuMAP2_06474 |
| CAPZB | HuMAP2_02165 HuMAP2_02236 HuMAP2_02991 HuMAP2_03613 HuMAP2_05890 HuMAP2_06451 HuMAP2_06474 |
| CAPZA2 | HuMAP2_02236 HuMAP2_05393 HuMAP2_06474 |