hu.MAP 2.0: Complex View

Human Protein Complex Map

Complex: HuMAP2_06511

Confidence: Medium

Genename	Protein Name	Links
ANP32A	Acidic leucine-rich nuclear phosphoprotein 32 family member A (Acidic nuclear phosphoprotein pp32) (pp32) (Leucine-rich acidic nuclear protein) (LANP) (Mapmodulin) (Potent heat-stable protein phosphatase 2A inhibitor I1PP2A) (Putative HLA-DR-associated protein I) (PHAPI)	UniProt NCBI
TRIM23	E3 ubiquitin-protein ligase TRIM23 (EC 2.3.2.27) (ADP-ribosylation factor domain-containing protein 1) (GTP-binding protein ARD-1) (RING finger protein 46) (RING-type E3 ubiquitin transferase TRIM23) (Tripartite motif-containing protein 23)	UniProt NCBI
ZC3H3	Zinc finger CCCH domain-containing protein 3 (Smad-interacting CPSF-like factor)	UniProt NCBI
ANP32B	Acidic leucine-rich nuclear phosphoprotein 32 family member B (Acidic protein rich in leucines) (Putative HLA-DR-associated protein I-2) (PHAPI2) (Silver-stainable protein SSP29)	UniProt NCBI
REPIN1	Replication initiator 1 (60 kDa origin-specific DNA-binding protein) (60 kDa replication initiation region protein) (ATT-binding protein) (DHFR oribeta-binding protein RIP60) (Zinc finger protein 464)	UniProt NCBI
NME8	Thioredoxin domain-containing protein 3 (NM23-H8) (NME/NM23 family member 8) (Spermatid-specific thioredoxin-2) (Sptrx-2)	UniProt NCBI
POTEB2	POTE ankyrin domain family member B2	UniProt NCBI
SET	Protein SET (HLA-DR-associated protein II) (Inhibitor of granzyme A-activated DNase) (IGAAD) (PHAPII) (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A) (Template-activating factor I) (TAF-I)	UniProt NCBI
ANP32E	Acidic leucine-rich nuclear phosphoprotein 32 family member E (LANP-like protein) (LANP-L)	UniProt NCBI
WDR55	WD repeat-containing protein 55	UniProt NCBI
ZNF672	Zinc finger protein 672	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:6987	0.000100616904936	0.181818181818	ANP32B ANP32A	ProTalpha C7 complex
CORUM:6988	0.000201152732593	0.181818181818	ANP32B ANP32A	ProTalpha C8 complex
CORUM:7299	0.000335119479973	0.181818181818	ANP32B ANP32A	ANP32A-ANP32B-PSMA3-PTMA-SLC25A5 complex
REAC:R-HSA-450520	0.00227917952008	0.181818181818	SET ANP32A	HuR (ELAVL1) binds and stabilizes mRNA
HPA:058010_03	0.00303893287583	0.454545454545	ANP32B ANP32E ANP32A SET WDR55	vagina; squamous epithelial cells[Uncertain,High]
HPA:050020_13	0.00341282761402	0.363636363636	ANP32E ANP32A SET ANP32B	spleen; cells in white pulp[Supported,High]
HPA:009010_03	0.00424232309562	0.454545454545	ANP32B ANP32E ANP32A SET WDR55	cervix, uterine; glandular cells[Uncertain,High]
HPA:032020_13	0.00569543098497	0.363636363636	ANP32E ANP32A SET ANP32B	pancreas; islets of Langerhans[Supported,High]
HPA:043040_13	0.00738969087226	0.363636363636	ANP32E ANP32A SET ANP32B	skin 1; melanocytes[Supported,High]
HPA:003010_03	0.0097397186666	0.454545454545	ANP32B ANP32E ANP32A SET WDR55	bone marrow; hematopoietic cells[Uncertain,High]
HPA:035010_13	0.0109999394382	0.363636363636	ANP32E ANP32A SET ANP32B	placenta; decidual cells[Supported,High]
HPA:009020_13	0.0118538724162	0.363636363636	ANP32E ANP32A SET ANP32B	cervix, uterine; squamous epithelial cells[Supported,High]
HPA:014020_13	0.0121490352329	0.363636363636	ANP32E ANP32A SET ANP32B	endometrium 2; glandular cells[Supported,High]
HPA:058010_13	0.0135444797522	0.363636363636	ANP32E ANP32A SET ANP32B	vagina; squamous epithelial cells[Supported,High]
HPA:007030_13	0.0140347128076	0.363636363636	ANP32E ANP32A SET ANP32B	cerebellum; cells in molecular layer[Supported,High]
HPA:040010_13	0.0152290845144	0.363636363636	ANP32E ANP32A SET ANP32B	seminal vesicle; glandular cells[Supported,High]
HPA:050020_03	0.0152290845144	0.363636363636	ANP32E ANP32A SET ANP32B	spleen; cells in white pulp[Uncertain,High]
HPA:011030_03	0.0155835999277	0.363636363636	ANP32E ANP32A WDR55 ANP32B	colon; peripheral nerve/ganglion[Uncertain,High]
HPA:056020_13	0.0155835999277	0.363636363636	ANP32E ANP32A SET ANP32B	tonsil; non-germinal center cells[Supported,High]
HPA:004020_13	0.015944127193	0.363636363636	ANP32E ANP32A SET ANP32B	breast; glandular cells[Supported,High]
HPA:009010_13	0.0163107298139	0.363636363636	ANP32E ANP32A SET ANP32B	cervix, uterine; glandular cells[Supported,High]
HPA:013020_13	0.0170624163486	0.363636363636	ANP32E ANP32A SET ANP32B	endometrium 1; glandular cells[Supported,High]
HPA:053010_13	0.0196812161348	0.363636363636	ANP32E ANP32A SET ANP32B	testis; Leydig cells[Supported,High]
HPA:056030_13	0.0214321465934	0.363636363636	ANP32E ANP32A SET ANP32B	tonsil; squamous epithelial cells[Supported,High]
HPA:032020_03	0.0218871024271	0.363636363636	ANP32E ANP32A SET ANP32B	pancreas; islets of Langerhans[Uncertain,High]
HPA:044010_13	0.0240222808154	0.363636363636	ANP32E ANP32A SET ANP32B	skin 2; epidermal cells[Supported,High]
HPA:039010_13	0.0242685680107	0.363636363636	ANP32E ANP32A SET ANP32B	salivary gland; glandular cells[Supported,High]
HPA:014010_02	0.027022139903	0.454545454545	ANP32B ANP32E ANP32A SET WDR55	endometrium 2; cells in endometrial stroma[Uncertain,Medium]
HPA:053010_12	0.0282007539104	0.454545454545	ANP32E ANP32A SET NME8 ANP32B	testis; Leydig cells[Supported,Medium]
HPA:018010_03	0.029953240213	0.454545454545	ANP32B ANP32E ANP32A SET WDR55	fallopian tube; glandular cells[Uncertain,High]
HPA:003010_13	0.0304584298787	0.363636363636	ANP32E ANP32A SET ANP32B	bone marrow; hematopoietic cells[Supported,High]
HPA:032010_03	0.0306774084007	0.454545454545	ANP32B ANP32E ANP32A SET WDR55	pancreas; exocrine glandular cells[Uncertain,High]
HPA:043040_03	0.0322462985737	0.363636363636	ANP32E ANP32A SET ANP32B	skin 1; melanocytes[Uncertain,High]
HPA:015010_13	0.0353944334695	0.363636363636	ANP32E ANP32A SET ANP32B	epididymis; glandular cells[Supported,High]
HPA:024020_13	0.0360499569285	0.363636363636	ANP32E ANP32A SET ANP32B	kidney; cells in tubules[Supported,High]
HPA:029010_03	0.0434995701567	0.454545454545	ANP32B ANP32E ANP32A SET WDR55	nasopharynx; respiratory epithelial cells[Uncertain,High]
HPA:007030_03	0.045790560885	0.363636363636	ANP32E ANP32A SET ANP32B	cerebellum; cells in molecular layer[Uncertain,High]
HPA:026020_02	0.0466655603456	0.545454545455	ANP32A ANP32B ANP32E ZC3H3 SET WDR55	liver; hepatocytes[Uncertain,Medium]
HPA:005010_03	0.0472078182062	0.454545454545	ANP32B ANP32E ANP32A SET WDR55	bronchus; respiratory epithelial cells[Uncertain,High]
HPA:055010_13	0.0477847920692	0.363636363636	ANP32E ANP32A SET ANP32B	thyroid gland; glandular cells[Supported,High]
HPA:009020_03	0.0477847920692	0.363636363636	ANP32E ANP32A SET ANP32B	cervix, uterine; squamous epithelial cells[Uncertain,High]

Edges

Protein 1	Protein 2	Score	Precision	Evidence
ANP32A	SET	0.988	0.901	boldt gupta_WMM fraction boldt_WMM
REPIN1	SET	0.92	0.844	hein_WMM bioplex (REPIN1,SET) bioplex_WMM youn_WMM hein (SET)
ANP32B	ANP32E	0.754	0.748	bioplex_WMM boldt gupta_WMM fraction boldt_WMM treiber_WMM
ANP32A	ANP32B	0.646	0.686	bioplex_WMM boldt gupta_WMM fraction boldt_WMM treiber_WMM
SET	ANP32E	0.494	0.62	boldt youn_WMM gupta_WMM fraction boldt_WMM
ANP32A	ANP32E	0.407	0.566	bioplex_WMM boldt gupta_WMM fraction boldt_WMM treiber_WMM
REPIN1	POTEB2	0.31	0.503	bioplex (REPIN1) bioplex_WMM
TRIM23	POTEB2	0.195	0.448	bioplex (TRIM23) bioplex_WMM
REPIN1	ZNF672	0.152	0.41	bioplex (REPIN1) bioplex_WMM
SET	ANP32B	0.062	0.34	boldt gupta_WMM fraction boldt_WMM
REPIN1	NME8	0.044	0.274	bioplex (REPIN1) bioplex_WMM
TRIM23	NME8	0.041	0.27	bioplex (TRIM23) bioplex_WMM
SET	ZC3H3	0.029	0.233	hein_WMM bioplex (ZC3H3) bioplex_WMM hein (SET)
SET	TRIM23	0.026	0.219	bioplex (TRIM23) bioplex_WMM
SET	WDR55	0.015	0.14	bioplex (WDR55) gupta_WMM fraction
SET	NME8	0.01	0.104	bioplex (NME8) bioplex_WMM boldt_WMM
SET	ZNF672	0.008	0.088	bioplex_WMM WMM_only
NME8	ZNF672	0.008	0.087	bioplex_WMM WMM_only
ANP32E	WDR55	0.007	0.004	gupta_WMM WMM_only
ANP32A	WDR55	0.007	0.0	gupta_WMM WMM_only
REPIN1	ANP32E	0.007	0.001	youn_WMM WMM_only
ANP32B	WDR55	0.007	0.003	gupta_WMM WMM_only
POTEB2	ZNF672	0.007	0.004	bioplex_WMM WMM_only
SET	POTEB2	0.007	0.007	bioplex_WMM WMM_only
NME8	POTEB2	0.007	0.006	bioplex_WMM WMM_only
ANP32A	NME8	0.007	0.004	WMM_only boldt_WMM
NME8	ANP32E	0.007	0.005	WMM_only boldt_WMM
TRIM23	ANP32B	0.007	0.006	bioplex (TRIM23)
REPIN1	ZC3H3	0.006	0.0	hein_WMM WMM_only
REPIN1	ANP32B	0.006	0.001	bioplex (REPIN1)
NME8	ANP32B	0.006	0.002	bioplex (NME8) boldt_WMM
ANP32A	ZC3H3	0.006	0.003	bioplex (ZC3H3)
ANP32A	TRIM23	0.006	0.006	bioplex (TRIM23)

Images

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Complex HuMAP2_06511 has an average edge precision of 0.228 which is ranked 5727 out of all 6965 complexes.

Related Complexes

Genename	Complexes
ANP32A	HuMAP2_00594 HuMAP2_01842 HuMAP2_03625 HuMAP2_06511
TRIM23	HuMAP2_00904 HuMAP2_03543 HuMAP2_05087 HuMAP2_05104 HuMAP2_06186 HuMAP2_06511
ZC3H3	HuMAP2_00860 HuMAP2_02859 HuMAP2_03534 HuMAP2_06511
ANP32B	HuMAP2_01842 HuMAP2_02276 HuMAP2_03625 HuMAP2_06511 HuMAP2_06551
REPIN1	HuMAP2_00594 HuMAP2_05087 HuMAP2_05104 HuMAP2_06186 HuMAP2_06511
NME8	HuMAP2_00904 HuMAP2_05087 HuMAP2_05104 HuMAP2_06186 HuMAP2_06511
POTEB2	HuMAP2_03442 HuMAP2_03543 HuMAP2_05087 HuMAP2_05104 HuMAP2_06186 HuMAP2_06511
SET	HuMAP2_00594 HuMAP2_01842 HuMAP2_03625 HuMAP2_05220 HuMAP2_06511
ANP32E	HuMAP2_01842 HuMAP2_02276 HuMAP2_03625 HuMAP2_06511
WDR55	HuMAP2_02694 HuMAP2_03625 HuMAP2_06511
ZNF672	HuMAP2_05087 HuMAP2_05104 HuMAP2_06186 HuMAP2_06511

hu.MAP 2.0: Complex View

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Complex: HuMAP2_06511