hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_06514
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| WDR46 | WD repeat-containing protein 46 (WD repeat-containing protein BING4) | UniProt NCBI |
| RRP7A | Ribosomal RNA-processing protein 7 homolog A (Gastric cancer antigen Zg14) | UniProt NCBI |
| NOL6 | Nucleolar protein 6 (Nucleolar RNA-associated protein) (Nrap) | UniProt NCBI |
| ZFP37 | Zinc finger protein 37 homolog (Zfp-37) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-6790901 | 4.60801423694e-05 | 0.75 | RRP7A NOL6 WDR46 | rRNA modification in the nucleus and cytosol |
| REAC:R-HSA-6791226 | 0.00130084091532 | 0.75 | RRP7A NOL6 WDR46 | Major pathway of rRNA processing in the nucleolus and cytosol |
| REAC:R-HSA-8868773 | 0.00152914291965 | 0.75 | RRP7A NOL6 WDR46 | rRNA processing in the nucleus and cytosol |
| REAC:R-HSA-72312 | 0.00178261497865 | 0.75 | RRP7A NOL6 WDR46 | rRNA processing |
| GO:0032545 | 0.00270494046827 | 0.5 | RRP7A NOL6 | CURI complex |
| GO:0034456 | 0.00270494046827 | 0.5 | RRP7A NOL6 | UTP-C complex |
| KEGG:03008 | 0.00582341320088 | 0.5 | RRP7A NOL6 | Ribosome biogenesis in eukaryotes |
| GO:0030684 | 0.0225145500348 | 0.75 | RRP7A NOL6 WDR46 | preribosome |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RRP7A | NOL6 | 0.971 | 0.882 | bioplex (RRP7A) bioplex_WMM youn_WMM gupta_WMM fraction |
| RRP7A | WDR46 | 0.029 | 0.23 | bioplex (WDR46) bioplex_WMM youn_WMM |
| ZFP37 | WDR46 | 0.026 | 0.218 | bioplex (WDR46) bioplex_WMM |
| NOL6 | WDR46 | 0.023 | 0.207 | bioplex (WDR46) bioplex_WMM youn_WMM treiber_WMM |
| RRP7A | ZFP37 | 0.008 | 0.041 | bioplex_WMM WMM_only |
| NOL6 | ZFP37 | 0.008 | 0.037 | bioplex_WMM WMM_only |
Images
Click to enlarge
Complex HuMAP2_06514 has an average edge precision of 0.269 which is ranked 5041 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| WDR46 | HuMAP2_03031 HuMAP2_06514 |
| RRP7A | HuMAP2_02186 HuMAP2_02370 HuMAP2_03435 HuMAP2_04524 HuMAP2_06514 |
| NOL6 | HuMAP2_02186 HuMAP2_02370 HuMAP2_04524 HuMAP2_06514 |
| ZFP37 | HuMAP2_03031 HuMAP2_06514 |