hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06520
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| FARSB | Phenylalanine--tRNA ligase beta subunit (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase beta subunit) (PheRS) | UniProt NCBI |
| FARSA | Phenylalanine--tRNA ligase alpha subunit (EC 6.1.1.20) (CML33) (Phenylalanyl-tRNA synthetase alpha subunit) (PheRS) | UniProt NCBI |
| PPP1R8 | Nuclear inhibitor of protein phosphatase 1 (NIPP-1) (Protein phosphatase 1 regulatory inhibitor subunit 8) [Includes: Activator of RNA decay (EC 3.1.4.-) (ARD-1)] | UniProt NCBI |
| IRF2BP1 | Interferon regulatory factor 2-binding protein 1 (IRF-2-binding protein 1) (IRF-2BP1) (Probable E3 ubiquitin-protein ligase IRF2BP1) (EC 2.3.2.27) (Probable RING-type E3 ubiquitin transferase IRF2BP1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00970 | 0.00188834163584 | 0.5 | FARSB FARSA | Aminoacyl-tRNA biosynthesis |
| GO:0009328 | 0.00270494046827 | 0.5 | FARSB FARSA | phenylalanine-tRNA ligase complex |
| REAC:R-HSA-379716 | 0.00276986547413 | 0.5 | FARSB FARSA | Cytosolic tRNA aminoacylation |
| GO:0006432 | 0.00811409485621 | 0.5 | FARSB FARSA | phenylalanyl-tRNA aminoacylation |
| REAC:R-HSA-379724 | 0.00862684444961 | 0.5 | FARSB FARSA | tRNA Aminoacylation |
| GO:0004826 | 0.0162267366884 | 0.5 | FARSB FARSA | phenylalanine-tRNA ligase activity |
| HPA:031020_23 | 0.0431522217761 | 0.5 | FARSA IRF2BP1 | ovary; ovarian stroma cells[Approved,High] |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| FARSA | FARSB | 0.996 | 0.928 | bioplex (FARSA) bioplex_WMM Guru youn_WMM Malo gupta_WMM fraction treiber_WMM |
| PPP1R8 | FARSB | 0.846 | 0.789 | bioplex_WMM youn_WMM fraction |
| FARSA | PPP1R8 | 0.28 | 0.486 | youn_WMM fraction |
| PPP1R8 | IRF2BP1 | 0.14 | 0.406 | boldt fraction boldt_WMM |
| IRF2BP1 | FARSB | 0.067 | 0.352 | youn_WMM fraction bioplex_WMM |
| FARSA | IRF2BP1 | 0.003 | 0.017 | youn_WMM fraction |
Images
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Complex HuMAP2_06520 has an average edge precision of 0.496 which is ranked 2520 out of all 6965 complexes.
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