hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06521
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ZFP36L2 | mRNA decay activator protein ZFP36L2 (Butyrate response factor 2) (EGF-response factor 2) (ERF-2) (TPA-induced sequence 11d) (Zinc finger protein 36, C3H1 type-like 2) (ZFP36-like 2) | UniProt NCBI |
| UBE3A | Ubiquitin-protein ligase E3A (EC 2.3.2.26) (E6AP ubiquitin-protein ligase) (HECT-type ubiquitin transferase E3A) (Human papillomavirus E6-associated protein) (Oncogenic protein-associated protein E6-AP) (Renal carcinoma antigen NY-REN-54) | UniProt NCBI |
| FBF1 | Fas-binding factor 1 (FBF-1) (Protein albatross) | UniProt NCBI |
| ANKFY1 | Rabankyrin-5 (Rank-5) (Ankyrin repeat and FYVE domain-containing protein 1) (Ankyrin repeats hooked to a zinc finger motif) | UniProt NCBI |
| ASB8 | Ankyrin repeat and SOCS box protein 8 (ASB-8) | UniProt NCBI |
| OTUD7B | OTU domain-containing protein 7B (EC 3.4.19.12) (Cellular zinc finger anti-NF-kappa-B protein) (Cezanne) (Zinc finger A20 domain-containing protein 1) (Zinc finger protein Cezanne) | UniProt NCBI |
| CASKIN1 | Caskin-1 (CASK-interacting protein 1) | UniProt NCBI |
| RNASEL | 2-5A-dependent ribonuclease (2-5A-dependent RNase) (EC 3.1.26.-) (Ribonuclease 4) (Ribonuclease L) (RNase L) | UniProt NCBI |
| HIF1AN | Hypoxia-inducible factor 1-alpha inhibitor (EC 1.14.11.30) (EC 1.14.11.n4) (Factor inhibiting HIF-1) (FIH-1) (Hypoxia-inducible factor asparagine hydroxylase) | UniProt NCBI |
| NOTCH3 | Neurogenic locus notch homolog protein 3 (Notch 3) [Cleaved into: Notch 3 extracellular truncation; Notch 3 intracellular domain] | UniProt NCBI |
| RIPK4 | NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| HIF1AN | CASKIN1 | 0.697 | 0.718 | bioplex (HIF1AN) bioplex_WMM |
| HIF1AN | UBE3A | 0.458 | 0.597 | bioplex (HIF1AN) bioplex_WMM |
| HIF1AN | OTUD7B | 0.413 | 0.571 | bioplex (HIF1AN) bioplex_WMM |
| HIF1AN | RNASEL | 0.317 | 0.509 | bioplex (HIF1AN) bioplex_WMM |
| HIF1AN | NOTCH3 | 0.278 | 0.485 | bioplex (HIF1AN) bioplex_WMM |
| HIF1AN | ASB8 | 0.142 | 0.406 | bioplex (ASB8,HIF1AN) bioplex_WMM |
| HIF1AN | ZFP36L2 | 0.122 | 0.394 | bioplex (HIF1AN) bioplex_WMM |
| HIF1AN | FBF1 | 0.117 | 0.39 | bioplex (HIF1AN) bioplex_WMM |
| HIF1AN | ANKFY1 | 0.073 | 0.355 | bioplex (HIF1AN) bioplex_WMM |
| RIPK4 | HIF1AN | 0.06 | 0.335 | bioplex (HIF1AN) bioplex_WMM |
| FBF1 | ZFP36L2 | 0.009 | 0.105 | bioplex_WMM gupta_WMM WMM_only |
| ZFP36L2 | OTUD7B | 0.009 | 0.095 | bioplex_WMM WMM_only |
| CASKIN1 | OTUD7B | 0.009 | 0.095 | bioplex_WMM WMM_only |
| CASKIN1 | ZFP36L2 | 0.009 | 0.095 | bioplex_WMM WMM_only |
| CASKIN1 | FBF1 | 0.009 | 0.095 | bioplex_WMM WMM_only |
| FBF1 | OTUD7B | 0.009 | 0.095 | bioplex_WMM WMM_only |
| RIPK4 | ZFP36L2 | 0.008 | 0.085 | bioplex_WMM WMM_only boldt_WMM |
| CASKIN1 | ASB8 | 0.008 | 0.085 | bioplex_WMM WMM_only |
| ASB8 | OTUD7B | 0.008 | 0.085 | bioplex_WMM WMM_only |
| ASB8 | FBF1 | 0.008 | 0.085 | bioplex_WMM WMM_only |
| ASB8 | ZFP36L2 | 0.008 | 0.085 | bioplex_WMM WMM_only |
| CASKIN1 | UBE3A | 0.008 | 0.08 | bioplex_WMM WMM_only |
| UBE3A | FBF1 | 0.008 | 0.08 | bioplex_WMM WMM_only |
| UBE3A | ZFP36L2 | 0.008 | 0.08 | bioplex_WMM WMM_only |
| UBE3A | OTUD7B | 0.008 | 0.08 | bioplex_WMM WMM_only |
| FBF1 | RNASEL | 0.008 | 0.066 | bioplex_WMM WMM_only |
| OTUD7B | RNASEL | 0.008 | 0.066 | bioplex_WMM WMM_only |
| CASKIN1 | RNASEL | 0.008 | 0.066 | bioplex_WMM WMM_only |
| ZFP36L2 | RNASEL | 0.008 | 0.066 | bioplex_WMM WMM_only |
| RIPK4 | CASKIN1 | 0.008 | 0.06 | bioplex_WMM WMM_only |
| RIPK4 | OTUD7B | 0.008 | 0.06 | bioplex_WMM WMM_only |
| RIPK4 | FBF1 | 0.008 | 0.06 | bioplex_WMM WMM_only |
| UBE3A | ASB8 | 0.008 | 0.028 | bioplex_WMM WMM_only |
| NOTCH3 | ZFP36L2 | 0.008 | 0.016 | bioplex_WMM WMM_only |
| NOTCH3 | OTUD7B | 0.008 | 0.016 | bioplex_WMM WMM_only |
| CASKIN1 | NOTCH3 | 0.008 | 0.016 | bioplex_WMM WMM_only |
| NOTCH3 | FBF1 | 0.008 | 0.016 | bioplex_WMM WMM_only |
| ASB8 | RNASEL | 0.007 | 0.005 | bioplex_WMM WMM_only |
| RIPK4 | ASB8 | 0.007 | 0.008 | bioplex_WMM WMM_only |
| UBE3A | RNASEL | 0.007 | 0.008 | bioplex_WMM WMM_only |
| RIPK4 | UBE3A | 0.007 | 0.003 | bioplex_WMM WMM_only |
| ANKFY1 | ZFP36L2 | 0.007 | 0.007 | bioplex_WMM youn_WMM WMM_only |
| ANKFY1 | OTUD7B | 0.007 | 0.006 | bioplex_WMM WMM_only |
| CASKIN1 | ANKFY1 | 0.007 | 0.006 | bioplex_WMM WMM_only |
| ANKFY1 | FBF1 | 0.007 | 0.006 | bioplex_WMM WMM_only |
| RIPK4 | RNASEL | 0.007 | 0.008 | bioplex_WMM WMM_only |
| NOTCH3 | ASB8 | 0.007 | 0.002 | bioplex_WMM WMM_only |
| NOTCH3 | UBE3A | 0.007 | 0.005 | bioplex_WMM WMM_only |
| NOTCH3 | RNASEL | 0.007 | 0.0 | bioplex_WMM WMM_only |
| RIPK4 | NOTCH3 | 0.007 | 0.004 | bioplex_WMM WMM_only |
| ANKFY1 | ASB8 | 0.007 | 0.002 | bioplex_WMM WMM_only |
| ANKFY1 | UBE3A | 0.007 | 0.005 | bioplex_WMM WMM_only |
| ANKFY1 | RNASEL | 0.007 | 0.007 | bioplex_WMM WMM_only |
| RIPK4 | ANKFY1 | 0.007 | 0.006 | bioplex_WMM WMM_only |
| ANKFY1 | NOTCH3 | 0.006 | 0.005 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_06521 has an average edge precision of 0.122 which is ranked 6860 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ZFP36L2 | HuMAP2_06521 |
| UBE3A | HuMAP2_06521 |
| FBF1 | HuMAP2_06521 |
| ANKFY1 | HuMAP2_03754 HuMAP2_05058 HuMAP2_06521 |
| ASB8 | HuMAP2_06521 |
| OTUD7B | HuMAP2_06521 |
| CASKIN1 | HuMAP2_03299 HuMAP2_06521 |
| RNASEL | HuMAP2_06521 |
| HIF1AN | HuMAP2_03299 HuMAP2_06521 |
| NOTCH3 | HuMAP2_06268 HuMAP2_06521 |
| RIPK4 | HuMAP2_01550 HuMAP2_06521 |