hu.MAP 2.0: Complex View

Human Protein Complex Map

Complex: HuMAP2_06534

Confidence: Medium

Genename	Protein Name	Links
F11R	Junctional adhesion molecule A (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (Platelet F11 receptor) (Platelet adhesion molecule 1) (PAM-1) (CD antigen CD321)	UniProt NCBI
ICA1L	Islet cell autoantigen 1-like protein (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 14 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 15 protein)	UniProt NCBI
PRXL2C	Peroxiredoxin-like 2C (AhpC/TSA antioxidant enzyme domain-containing protein 1) (Thioredoxin-like protein AAED1)	UniProt NCBI
IL12A	Interleukin-12 subunit alpha (IL-12A) (Cytotoxic lymphocyte maturation factor 35 kDa subunit) (CLMF p35) (IL-12 subunit p35) (NK cell stimulatory factor chain 1) (NKSF1)	UniProt NCBI
FAM3D	Protein FAM3D	UniProt NCBI
GPATCH2	G patch domain-containing protein 2	UniProt NCBI
PKD2	Polycystin-2 (PC2) (Autosomal dominant polycystic kidney disease type II protein) (Polycystic kidney disease 2 protein) (Polycystwin) (R48321) (Transient receptor potential cation channel subfamily P member 2)	UniProt NCBI
C3orf14	Uncharacterized protein C3orf14	UniProt NCBI
CEP89	Centrosomal protein of 89 kDa (Cep89) (Centrosomal protein 123) (Cep123) (Coiled-coil domain-containing protein 123)	UniProt NCBI
JAM3	Junctional adhesion molecule C (JAM-C) (JAM-2) (Junctional adhesion molecule 3) (JAM-3) [Cleaved into: Soluble form of JAM-C (sJAM-C)]	UniProt NCBI
PICK1	PRKCA-binding protein (Protein interacting with C kinase 1) (Protein kinase C-alpha-binding protein)	UniProt NCBI
ICA1	Islet cell autoantigen 1 (69 kDa islet cell autoantigen) (ICA69) (Islet cell autoantigen p69) (ICAp69) (p69)	UniProt NCBI
PKD2L2	Polycystic kidney disease 2-like 2 protein (Polycystin-2L2) (Polycystin-L2)	UniProt NCBI
FAM117A	Protein FAM117A (C/EBP-induced protein)	UniProt NCBI
KLHL11	Kelch-like protein 11	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
KEGG:04940	0.0202125839972	0.133333333333	IL12A ICA1	Type I diabetes mellitus
REAC:R-HSA-202733	0.0359279974154	0.2	PICK1 JAM3 F11R	Cell surface interactions at the vascular wall
CORUM:1071	0.0498572752401	0.0666666666667	PKD2	PKD2-FPC complex
CORUM:2016	0.0498572752401	0.0666666666667	IL12A	IL12A homodimer complex
CORUM:2018	0.0498572752401	0.0666666666667	IL12A	IL12A-IL12B complex
CORUM:5548	0.0498572752401	0.0666666666667	IL12A	IL12A-IL12B complex

Edges

Protein 1	Protein 2	Score	Precision	Evidence
ICA1	PICK1	0.993	0.918	bioplex (PICK1) bioplex_WMM
ICA1L	PICK1	0.971	0.884	bioplex (PICK1) bioplex_WMM
PRXL2C	PICK1	0.785	0.756	bioplex (PICK1) bioplex_WMM
CEP89	PICK1	0.752	0.745	bioplex (PICK1) bioplex_WMM
PICK1	F11R	0.588	0.662	bioplex (PICK1) bioplex_WMM
PICK1	C3orf14	0.408	0.567	bioplex (PICK1) bioplex_WMM
PICK1	FAM117A	0.139	0.406	bioplex (PICK1) bioplex_WMM
IL12A	F11R	0.114	0.383	bioplex (IL12A) bioplex_WMM
PICK1	KLHL11	0.112	0.38	bioplex (PICK1) bioplex_WMM
PICK1	JAM3	0.078	0.352	bioplex (PICK1) bioplex_WMM
PKD2	PICK1	0.07	0.348	bioplex (PICK1) bioplex_WMM
PKD2	FAM3D	0.052	0.301	bioplex (FAM3D) bioplex_WMM
GPATCH2	PICK1	0.045	0.283	bioplex (PICK1) bioplex_WMM
PKD2	PKD2L2	0.041	0.269	bioplex (PKD2L2) bioplex_WMM
PRXL2C	FAM117A	0.009	0.095	bioplex_WMM WMM_only
PRXL2C	ICA1L	0.009	0.095	bioplex_WMM WMM_only
ICA1L	FAM117A	0.009	0.095	bioplex_WMM WMM_only
C3orf14	FAM117A	0.009	0.095	bioplex_WMM WMM_only
PRXL2C	C3orf14	0.009	0.095	bioplex_WMM WMM_only
ICA1L	C3orf14	0.009	0.095	bioplex_WMM WMM_only
GPATCH2	ICA1L	0.008	0.091	bioplex_WMM WMM_only
ICA1	ICA1L	0.008	0.091	bioplex_WMM WMM_only
GPATCH2	FAM117A	0.008	0.091	bioplex_WMM WMM_only
ICA1	PRXL2C	0.008	0.091	bioplex_WMM WMM_only
ICA1	C3orf14	0.008	0.091	bioplex_WMM WMM_only
GPATCH2	PRXL2C	0.008	0.091	bioplex_WMM WMM_only
ICA1	FAM117A	0.008	0.091	bioplex_WMM WMM_only
GPATCH2	C3orf14	0.008	0.091	bioplex_WMM WMM_only
CEP89	FAM117A	0.008	0.087	bioplex_WMM WMM_only
PRXL2C	JAM3	0.008	0.087	bioplex_WMM WMM_only
JAM3	C3orf14	0.008	0.087	bioplex_WMM WMM_only
CEP89	PRXL2C	0.008	0.087	bioplex_WMM WMM_only
CEP89	ICA1L	0.008	0.087	bioplex_WMM WMM_only
JAM3	FAM117A	0.008	0.087	bioplex_WMM WMM_only
ICA1L	JAM3	0.008	0.087	bioplex_WMM WMM_only
PRXL2C	F11R	0.008	0.085	bioplex_WMM WMM_only
GPATCH2	ICA1	0.008	0.085	bioplex_WMM WMM_only
F11R	FAM117A	0.008	0.085	bioplex_WMM WMM_only
ICA1L	F11R	0.008	0.085	bioplex_WMM WMM_only
F11R	C3orf14	0.008	0.085	bioplex_WMM WMM_only
JAM3	F11R	0.008	0.081	bioplex_WMM gupta_WMM WMM_only
GPATCH2	CEP89	0.008	0.067	bioplex_WMM WMM_only
ICA1	JAM3	0.008	0.067	bioplex_WMM WMM_only
CEP89	ICA1	0.008	0.067	bioplex_WMM WMM_only
GPATCH2	JAM3	0.008	0.067	bioplex_WMM WMM_only
KLHL11	FAM117A	0.008	0.066	bioplex_WMM WMM_only
ICA1L	KLHL11	0.008	0.066	bioplex_WMM WMM_only
KLHL11	C3orf14	0.008	0.066	bioplex_WMM WMM_only
PRXL2C	KLHL11	0.008	0.066	bioplex_WMM WMM_only
ICA1	F11R	0.008	0.06	bioplex_WMM WMM_only
GPATCH2	F11R	0.008	0.06	bioplex_WMM WMM_only
CEP89	JAM3	0.008	0.06	bioplex_WMM WMM_only
CEP89	F11R	0.008	0.04	bioplex_WMM WMM_only
ICA1	KLHL11	0.008	0.034	bioplex_WMM WMM_only
GPATCH2	KLHL11	0.008	0.034	bioplex_WMM WMM_only
PKD2	ICA1L	0.008	0.02	bioplex_WMM WMM_only
PKD2	PRXL2C	0.008	0.02	bioplex_WMM WMM_only
PKD2	FAM117A	0.008	0.02	bioplex_WMM WMM_only
PKD2	C3orf14	0.008	0.02	bioplex_WMM WMM_only
CEP89	KLHL11	0.008	0.012	bioplex_WMM WMM_only
JAM3	KLHL11	0.008	0.012	bioplex_WMM WMM_only
F11R	KLHL11	0.007	0.005	bioplex_WMM WMM_only
PKD2	GPATCH2	0.007	0.009	bioplex_WMM WMM_only
PKD2	ICA1	0.007	0.009	bioplex_WMM WMM_only
PKD2	JAM3	0.007	0.007	bioplex_WMM WMM_only
PKD2	CEP89	0.007	0.007	bioplex_WMM WMM_only
CEP89	C3orf14	0.007	0.01	bioplex_WMM gupta (C3orf14,CEP89)
PKD2	F11R	0.007	0.004	bioplex_WMM WMM_only
PKD2	KLHL11	0.007	0.004	bioplex_WMM WMM_only

Images

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Complex HuMAP2_06534 has an average edge precision of 0.154 which is ranked 6674 out of all 6965 complexes.

Related Complexes

Genename	Complexes
F11R	HuMAP2_02969 HuMAP2_03208 HuMAP2_05676 HuMAP2_06534
ICA1L	HuMAP2_00559 HuMAP2_03208 HuMAP2_06534
PRXL2C	HuMAP2_00559 HuMAP2_03208 HuMAP2_06534
IL12A	HuMAP2_02969 HuMAP2_05676 HuMAP2_06534
FAM3D	HuMAP2_00110 HuMAP2_06534
GPATCH2	HuMAP2_00169 HuMAP2_00633 HuMAP2_05740 HuMAP2_06534
PKD2	HuMAP2_00110 HuMAP2_06534
C3orf14	HuMAP2_06534
CEP89	HuMAP2_00559 HuMAP2_02644 HuMAP2_03208 HuMAP2_05248 HuMAP2_06534 HuMAP2_06786
JAM3	HuMAP2_02142 HuMAP2_06289 HuMAP2_06534 HuMAP2_06933
PICK1	HuMAP2_00559 HuMAP2_03208 HuMAP2_06534
ICA1	HuMAP2_00559 HuMAP2_04281 HuMAP2_04564 HuMAP2_05256 HuMAP2_06534 HuMAP2_06873
PKD2L2	HuMAP2_00110 HuMAP2_06534
FAM117A	HuMAP2_06534
KLHL11	HuMAP2_03890 HuMAP2_05546 HuMAP2_06534

hu.MAP 2.0: Complex View

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Complex: HuMAP2_06534