hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06542
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RBM10 | RNA-binding protein 10 (G patch domain-containing protein 9) (RNA-binding motif protein 10) (RNA-binding protein S1-1) (S1-1) | UniProt NCBI |
| RBM5 | RNA-binding protein 5 (Protein G15) (Putative tumor suppressor LUCA15) (RNA-binding motif protein 5) (Renal carcinoma antigen NY-REN-9) | UniProt NCBI |
| SFSWAP | Splicing factor, suppressor of white-apricot homolog (Splicing factor, arginine/serine-rich 8) (Suppressor of white apricot protein homolog) | UniProt NCBI |
| U2SURP | U2 snRNP-associated SURP motif-containing protein (140 kDa Ser/Arg-rich domain protein) (U2-associated protein SR140) | UniProt NCBI |
| CHERP | Calcium homeostasis endoplasmic reticulum protein (ERPROT 213-21) (SR-related CTD-associated factor 6) | UniProt NCBI |
| RBM17 | Splicing factor 45 (45 kDa-splicing factor) (RNA-binding motif protein 17) | UniProt NCBI |
| ZRSR2P1 | NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:2755 | 1.11287657592e-05 | 0.5 | CHERP RBM17 U2SURP | 17S U2 snRNP |
| REAC:R-HSA-72163 | 4.76078002862e-05 | 0.666666666667 | CHERP RBM5 U2SURP RBM17 | mRNA Splicing - Major Pathway |
| REAC:R-HSA-72172 | 5.67951064007e-05 | 0.666666666667 | CHERP RBM5 U2SURP RBM17 | mRNA Splicing |
| REAC:R-HSA-72203 | 0.000144935124655 | 0.666666666667 | CHERP RBM5 U2SURP RBM17 | Processing of Capped Intron-Containing Pre-mRNA |
| WP:WP411 | 0.000468249477071 | 0.5 | RBM17 RBM5 SFSWAP | mRNA Processing |
| KEGG:03040 | 0.000590221771159 | 0.5 | CHERP RBM17 U2SURP | Spliceosome |
| GO:0000377 | 0.00115243061952 | 0.833333333333 | CHERP RBM17 RBM5 U2SURP SFSWAP | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile |
| GO:0000398 | 0.00115243061952 | 0.833333333333 | CHERP RBM17 RBM5 U2SURP SFSWAP | mRNA splicing, via spliceosome |
| GO:0000375 | 0.00120907776661 | 0.833333333333 | CHERP RBM17 RBM5 U2SURP SFSWAP | RNA splicing, via transesterification reactions |
| GO:0008380 | 0.00270779091032 | 0.833333333333 | CHERP RBM17 RBM5 U2SURP SFSWAP | RNA splicing |
| GO:0006397 | 0.00390084589509 | 0.833333333333 | CHERP RBM17 RBM5 U2SURP SFSWAP | mRNA processing |
| REAC:R-HSA-8953854 | 0.00833913786065 | 0.666666666667 | CHERP RBM5 U2SURP RBM17 | Metabolism of RNA |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CHERP | U2SURP | 0.999 | 0.949 | hein_WMM bioplex_WMM youn_WMM Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| RBM17 | CHERP | 0.977 | 0.893 | hein_WMM bioplex (RBM17) bioplex_WMM youn_WMM gupta_WMM fraction boldt_WMM |
| RBM17 | U2SURP | 0.387 | 0.551 | hein_WMM bioplex (RBM17,U2SURP) bioplex_WMM youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
| RBM10 | RBM17 | 0.147 | 0.408 | hein_WMM bioplex (RBM17) bioplex_WMM youn_WMM gupta_WMM treiber_WMM |
| RBM5 | RBM17 | 0.119 | 0.392 | hein_WMM bioplex (RBM17) bioplex_WMM youn_WMM |
| SFSWAP | RBM17 | 0.024 | 0.215 | bioplex (RBM17) bioplex_WMM youn_WMM |
| ZRSR2P1 | RBM17 | 0.023 | 0.209 | bioplex (RBM17) bioplex_WMM |
| RBM5 | CHERP | 0.012 | 0.149 | hein_WMM bioplex_WMM youn_WMM WMM_only treiber_WMM |
| ZRSR2P1 | U2SURP | 0.01 | 0.112 | bioplex_WMM WMM_only |
| RBM10 | RBM5 | 0.01 | 0.1 | hein_WMM bioplex_WMM youn_WMM WMM_only treiber_WMM |
| RBM10 | CHERP | 0.009 | 0.111 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
| RBM5 | U2SURP | 0.009 | 0.109 | hein_WMM bioplex_WMM youn_WMM WMM_only treiber_WMM |
| SFSWAP | ZRSR2P1 | 0.009 | 0.092 | bioplex_WMM WMM_only |
| ZRSR2P1 | CHERP | 0.009 | 0.09 | bioplex_WMM WMM_only |
| SFSWAP | CHERP | 0.009 | 0.095 | bioplex_WMM youn_WMM WMM_only treiber_WMM |
| SFSWAP | U2SURP | 0.008 | 0.096 | bioplex_WMM youn_WMM WMM_only treiber_WMM |
| RBM5 | ZRSR2P1 | 0.008 | 0.033 | bioplex_WMM WMM_only |
| SFSWAP | RBM10 | 0.008 | 0.032 | hein_WMM bioplex_WMM youn_WMM WMM_only treiber_WMM |
| SFSWAP | RBM5 | 0.007 | 0.007 | bioplex_WMM youn_WMM WMM_only treiber_WMM |
| RBM10 | U2SURP | 0.007 | 0.008 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only boldt_WMM treiber_WMM |
| RBM10 | ZRSR2P1 | 0.007 | 0.006 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_06542 has an average edge precision of 0.222 which is ranked 5827 out of all 6965 complexes.
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