hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06548
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PPA1 | Inorganic pyrophosphatase (EC 3.6.1.1) (Pyrophosphate phospho-hydrolase) (PPase) | UniProt NCBI |
| SLC9A3R1 | Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (NHERF-1) (Ezrin-radixin-moesin-binding phosphoprotein 50) (EBP50) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform A3 regulatory factor 1) | UniProt NCBI |
| ALKBH6 | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 6 (EC 1.14.11.-) (Alkylated DNA repair protein alkB homolog 6) | UniProt NCBI |
| RNPEP | Aminopeptidase B (AP-B) (EC 3.4.11.6) (Arginine aminopeptidase) (Arginyl aminopeptidase) | UniProt NCBI |
| CTBP2 | C-terminal-binding protein 2 (CtBP2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:687 | 0.0499494897235 | 0.2 | SLC9A3R1 | CFTR-NHERF-beta(2)AR signaling complex |
| CORUM:6702 | 0.0499494897235 | 0.2 | SLC9A3R1 | CXCR2-NHERF1-PLC-beta-3 complex |
| CORUM:6788 | 0.0499494897235 | 0.2 | SLC9A3R1 | SLC9A3R1-ACTN4 complex |
| CORUM:6790 | 0.0499494897235 | 0.2 | SLC9A3R1 | NHERF1-PRKCZ complex |
| CORUM:6791 | 0.0499494897235 | 0.2 | SLC9A3R1 | NHERF1-NPT2A-EZR complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RNPEP | PPA1 | 0.046 | 0.293 | bioplex_WMM fraction |
| PPA1 | CTBP2 | 0.035 | 0.261 | bioplex_WMM youn_WMM gupta_WMM fraction treiber_WMM |
| PPA1 | SLC9A3R1 | 0.031 | 0.241 | bioplex_WMM youn_WMM gupta_WMM fraction |
| ALKBH6 | PPA1 | 0.025 | 0.213 | fraction |
| CTBP2 | SLC9A3R1 | 0.007 | 0.005 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| RNPEP | CTBP2 | 0.007 | 0.003 | bioplex_WMM WMM_only |
| RNPEP | SLC9A3R1 | 0.004 | 0.014 | bioplex_WMM WMM_only treiber_WMM |
Images
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Complex HuMAP2_06548 has an average edge precision of 0.147 which is ranked 6720 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PPA1 | HuMAP2_02492 HuMAP2_04965 HuMAP2_06360 HuMAP2_06548 |
| SLC9A3R1 | HuMAP2_05594 HuMAP2_06180 HuMAP2_06548 HuMAP2_06957 |
| ALKBH6 | HuMAP2_01614 HuMAP2_03934 HuMAP2_05261 HuMAP2_06340 HuMAP2_06548 |
| RNPEP | HuMAP2_00452 HuMAP2_03318 HuMAP2_03586 HuMAP2_03858 HuMAP2_06360 HuMAP2_06548 |
| CTBP2 | HuMAP2_03746 HuMAP2_06548 |