hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06553
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| AURKA | Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (hARK1) (Breast tumor-amplified kinase) (Serine/threonine-protein kinase 15) (Serine/threonine-protein kinase 6) (Serine/threonine-protein kinase aurora-A) | UniProt NCBI |
| CEP192 | Centrosomal protein of 192 kDa (Cep192) (Cep192/SPD-2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP2361 | 0.000121088932808 | 1.0 | CEP192 AURKA | Gastric Cancer Network 1 |
| REAC:R-HSA-8854518 | 0.00404735516163 | 1.0 | CEP192 AURKA | AURKA Activation by TPX2 |
| REAC:R-HSA-2565942 | 0.00584226918984 | 1.0 | CEP192 AURKA | Regulation of PLK1 Activity at G2/M Transition |
| REAC:R-HSA-8854521 | 0.0249595281251 | 0.5 | AURKA | Interaction between PHLDA1 and AURKA |
| REAC:R-HSA-69275 | 0.0300912057669 | 1.0 | CEP192 AURKA | G2/M Transition |
| REAC:R-HSA-453274 | 0.0307297326061 | 1.0 | CEP192 AURKA | Mitotic G2-G2/M phases |
| CORUM:6412 | 0.0499173803268 | 0.5 | AURKA | AURKA-HDAC6 cilia-disassembly complex |
| CORUM:6740 | 0.0499173803268 | 0.5 | AURKA | AURKA-INPP5E complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CEP192 | AURKA | 0.521 | 0.634 | bioplex (AURKA) bioplex_WMM youn_WMM gupta_WMM |
Images
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Complex HuMAP2_06553 has an average edge precision of 0.634 which is ranked 1750 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| AURKA | HuMAP2_02352 HuMAP2_03018 HuMAP2_06553 |
| CEP192 | HuMAP2_02023 HuMAP2_02573 HuMAP2_06553 |