hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06558
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PRRG1 | Transmembrane gamma-carboxyglutamic acid protein 1 (Proline-rich gamma-carboxyglutamic acid protein 1) (Proline-rich Gla protein 1) | UniProt NCBI |
| TMEM255A | Transmembrane protein 255A (Protein FAM70A) | UniProt NCBI |
| GCA | Grancalcin | UniProt NCBI |
| WWP2 | NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 2.3.2.26) (Atrophin-1-interacting protein 2) (AIP2) (HECT-type E3 ubiquitin transferase WWP2) (WW domain-containing protein 2) | UniProt NCBI |
| WWP1 | NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 2.3.2.26) (Atrophin-1-interacting protein 5) (AIP5) (HECT-type E3 ubiquitin transferase WWP1) (TGIF-interacting ubiquitin ligase 1) (Tiul1) (WW domain-containing protein 1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04120 | 0.0353865382697 | 0.4 | WWP1 WWP2 | Ubiquitin mediated proteolysis |
| CORUM:5371 | 0.0499494897235 | 0.2 | GCA | Grancalcin-sorcin complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| TMEM255A | GCA | 0.467 | 0.604 | bioplex (TMEM255A) bioplex_WMM |
| WWP2 | TMEM255A | 0.096 | 0.358 | bioplex (TMEM255A) bioplex_WMM |
| WWP2 | PRRG1 | 0.09 | 0.355 | bioplex (WWP2) bioplex_WMM |
| WWP1 | TMEM255A | 0.056 | 0.315 | bioplex (TMEM255A) bioplex_WMM |
| WWP1 | WWP2 | 0.03 | 0.237 | bioplex_WMM WMM_only treiber_WMM |
| WWP1 | GCA | 0.007 | 0.004 | bioplex_WMM WMM_only |
| WWP2 | GCA | 0.007 | 0.003 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_06558 has an average edge precision of 0.268 which is ranked 5075 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PRRG1 | HuMAP2_06558 |
| TMEM255A | HuMAP2_06558 |
| GCA | HuMAP2_06558 |
| WWP2 | HuMAP2_06558 |
| WWP1 | HuMAP2_02724 HuMAP2_04200 HuMAP2_06558 |