hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_06565
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| EHD4 | EH domain-containing protein 4 (Hepatocellular carcinoma-associated protein 10/11) (PAST homolog 4) | UniProt NCBI |
| ACOT13 | Acyl-coenzyme A thioesterase 13 (Acyl-CoA thioesterase 13) (EC 3.1.2.-) (Thioesterase superfamily member 2) [Cleaved into: Acyl-coenzyme A thioesterase 13, N-terminally processed] | UniProt NCBI |
| EHD3 | EH domain-containing protein 3 (PAST homolog 3) | UniProt NCBI |
| VPS45 | Vacuolar protein sorting-associated protein 45 (h-VPS45) (hlVps45) | UniProt NCBI |
| RBSN | Rabenosyn-5 (110 kDa protein) (FYVE finger-containing Rab5 effector protein rabenosyn-5) (RAB effector RBSN) (Zinc finger FYVE domain-containing protein 20) | UniProt NCBI |
| GALE | UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase) (UDP-N-acetylgalactosamine 4-epimerase) (UDP-GalNAc 4-epimerase) (UDP-N-acetylglucosamine 4-epimerase) (UDP-GlcNAc 4-epimerase) (EC 5.1.3.7) (UDP-galactose 4-epimerase) | UniProt NCBI |
| STX16 | Syntaxin-16 (Syn16) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04144 | 9.9712356068e-05 | 0.571428571429 | EHD4 VPS45 EHD3 RBSN | Endocytosis |
| REAC:R-HSA-983231 | 0.0067714376714 | 0.428571428571 | RBSN EHD3 VPS45 | Factors involved in megakaryocyte development and platelet production |
| REAC:R-HSA-6811438 | 0.0296729390946 | 0.285714285714 | STX16 VPS45 | Intra-Golgi traffic |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| VPS45 | RBSN | 0.987 | 0.901 | bioplex (RBSN,VPS45) bioplex_WMM youn_WMM Malo gupta_WMM fraction boldt_WMM |
| VPS45 | STX16 | 0.703 | 0.723 | bioplex (VPS45) bioplex_WMM youn_WMM gupta_WMM boldt_WMM |
| RBSN | EHD3 | 0.191 | 0.444 | bioplex (RBSN) bioplex_WMM |
| VPS45 | ACOT13 | 0.094 | 0.357 | fraction |
| RBSN | EHD4 | 0.083 | 0.349 | bioplex (RBSN) bioplex_WMM |
| GALE | EHD4 | 0.028 | 0.231 | Guru fraction |
| STX16 | RBSN | 0.008 | 0.066 | bioplex_WMM youn_WMM WMM_only |
| VPS45 | EHD3 | 0.008 | 0.066 | bioplex_WMM WMM_only |
| EHD3 | EHD4 | 0.008 | 0.011 | bioplex_WMM WMM_only boldt_WMM |
| STX16 | EHD4 | 0.007 | 0.006 | gupta_WMM WMM_only |
| VPS45 | EHD4 | 0.006 | 0.004 | bioplex_WMM Guru youn_WMM gupta_WMM fraction |
| GALE | ACOT13 | 0.004 | 0.015 | fraction |
Images
Click to enlarge
Complex HuMAP2_06565 has an average edge precision of 0.264 which is ranked 5140 out of all 6965 complexes.
Related Complexes