hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06568
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| BCAN | Brevican core protein (Brain-enriched hyaluronan-binding protein) (BEHAB) (Chondroitin sulfate proteoglycan 7) | UniProt NCBI |
| VCAN | Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Glial hyaluronate-binding protein) (GHAP) (Large fibroblast proteoglycan) (PG-M) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-3595177 | 3.51943927099e-05 | 1.0 | BCAN VCAN | Defective CHSY1 causes TPBS |
| REAC:R-HSA-3595172 | 3.51943927099e-05 | 1.0 | BCAN VCAN | Defective CHST3 causes SEDCJD |
| REAC:R-HSA-3595174 | 3.51943927099e-05 | 1.0 | BCAN VCAN | Defective CHST14 causes EDS, musculocontractural type |
| REAC:R-HSA-2022923 | 7.54165558069e-05 | 1.0 | BCAN VCAN | Dermatan sulfate biosynthesis |
| REAC:R-HSA-2024101 | 0.000130722030065 | 1.0 | BCAN VCAN | CS/DS degradation |
| REAC:R-HSA-2022870 | 0.000256416289743 | 1.0 | BCAN VCAN | Chondroitin sulfate biosynthesis |
| REAC:R-HSA-3560783 | 0.000286582912066 | 1.0 | BCAN VCAN | Defective B4GALT7 causes EDS, progeroid type |
| REAC:R-HSA-4420332 | 0.000286582912066 | 1.0 | BCAN VCAN | Defective B3GALT6 causes EDSP2 and SEMDJL1 |
| REAC:R-HSA-3560801 | 0.000286582912066 | 1.0 | BCAN VCAN | Defective B3GAT3 causes JDSSDHD |
| REAC:R-HSA-1971475 | 0.000462554875615 | 1.0 | BCAN VCAN | A tetrasaccharide linker sequence is required for GAG synthesis |
| REAC:R-HSA-3560782 | 0.00124185928562 | 1.0 | BCAN VCAN | Diseases associated with glycosaminoglycan metabolism |
| WP:WP2431 | 0.00145902849501 | 1.0 | BCAN VCAN | Spinal Cord Injury |
| REAC:R-HSA-1793185 | 0.00181167326283 | 1.0 | BCAN VCAN | Chondroitin sulfate/dermatan sulfate metabolism |
| REAC:R-HSA-1638091 | 0.00205300624141 | 1.0 | BCAN VCAN | Heparan sulfate/heparin (HS-GAG) metabolism |
| REAC:R-HSA-3000178 | 0.00359485582679 | 1.0 | BCAN VCAN | ECM proteoglycans |
| REAC:R-HSA-1630316 | 0.0102315127378 | 1.0 | BCAN VCAN | Glycosaminoglycan metabolism |
| REAC:R-HSA-3781865 | 0.0125744537382 | 1.0 | BCAN VCAN | Diseases of glycosylation |
| GO:0030208 | 0.0247952876258 | 1.0 | BCAN VCAN | dermatan sulfate biosynthetic process |
| GO:0030207 | 0.029754345151 | 1.0 | BCAN VCAN | chondroitin sulfate catabolic process |
| GO:0030205 | 0.029754345151 | 1.0 | BCAN VCAN | dermatan sulfate metabolic process |
| GO:0050651 | 0.0410249304355 | 1.0 | BCAN VCAN | dermatan sulfate proteoglycan biosynthetic process |
| GO:0050655 | 0.0473364581948 | 1.0 | BCAN VCAN | dermatan sulfate proteoglycan metabolic process |
| HP:0007643 | 0.0497341708567 | 0.5 | VCAN | Peripheral tractional retinal detachment |
| HP:0030663 | 0.0497341708567 | 0.5 | VCAN | Optically empty vitreous |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| VCAN | BCAN | 0.034 | 0.263 | bioplex (BCAN) bioplex_WMM |
Images
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Complex HuMAP2_06568 has an average edge precision of 0.263 which is ranked 5168 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| BCAN | HuMAP2_06568 |
| VCAN | HuMAP2_01081 HuMAP2_06568 |