hu.MAP 2.0: Complex View

Human Protein Complex Map

Genename	Protein Name	Links
SNTB2	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin-3) (SNT3) (Syntrophin-like) (SNTL)	UniProt NCBI
DTNA	Dystrobrevin alpha (DTN-A) (Alpha-dystrobrevin) (Dystrophin-related protein 3)	UniProt NCBI
SNTA1	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin-1)	UniProt NCBI
SNTB1	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (BSYN2) (Syntrophin-2) (Tax interaction protein 43) (TIP-43)	UniProt NCBI
DTNB	Dystrobrevin beta (DTN-B) (Beta-dystrobrevin)	UniProt NCBI
SNTG2	Gamma-2-syntrophin (G2SYN) (Syntrophin-5) (SYN5)	UniProt NCBI
DMD	Dystrophin	UniProt NCBI
CTNNAL1	Alpha-catulin (Alpha-catenin-related protein) (ACRP) (Catenin alpha-like protein 1)	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0016010	9.17026171826e-10	0.625	DMD SNTA1 SNTG2 SNTB2 SNTB1	dystrophin-associated glycoprotein complex
GO:0090665	9.17026171826e-10	0.625	DMD SNTA1 SNTG2 SNTB2 SNTB1	glycoprotein complex
CORUM:7341	1.16880143691e-05	0.25	DTNA CTNNAL1	CTNNAL1-DNTA complex
GO:0016013	2.03382379613e-05	0.375	SNTA1 SNTG2 DMD	syntrophin complex
GO:0098797	0.0348252240904	0.625	DMD SNTA1 SNTG2 SNTB2 SNTB1	plasma membrane protein complex
GO:1902083	0.0378589948753	0.25	SNTA1 DMD	negative regulation of peptidyl-cysteine S-nitrosylation
CORUM:4095	0.0497224828424	0.125	CTNNAL1	CTNNAL1-CTNNB1 complex

Protein 1	Protein 2	Score	Precision	Evidence
DMD	CTNNAL1	0.939	0.85	bioplex (DMD) bioplex_WMM fraction
DMD	SNTB1	0.904	0.827	bioplex (DMD) bioplex_WMM
DMD	SNTG2	0.867	0.801	bioplex (SNTG2) bioplex_WMM
SNTB1	SNTG2	0.842	0.786	bioplex (SNTG2) bioplex_WMM
DMD	DTNB	0.656	0.694	bioplex (DMD) bioplex_WMM
DMD	DTNA	0.649	0.687	bioplex (DMD) bioplex_WMM boldt_WMM
DMD	SNTA1	0.578	0.66	bioplex (DMD) bioplex_WMM
DTNA	SNTG2	0.538	0.642	bioplex (SNTG2) bioplex_WMM
DTNB	SNTG2	0.445	0.589	bioplex (SNTG2) bioplex_WMM
SNTA1	SNTG2	0.344	0.534	bioplex (SNTG2) bioplex_WMM
SNTB2	SNTG2	0.268	0.482	bioplex (SNTG2) bioplex_WMM
DMD	SNTB2	0.242	0.468	bioplex (DMD) bioplex_WMM
CTNNAL1	SNTG2	0.23	0.468	bioplex (SNTG2) bioplex_WMM
SNTB1	SNTA1	0.015	0.144	bioplex_WMM WMM_only
SNTB2	DTNB	0.013	0.144	bioplex_WMM gupta_WMM WMM_only
SNTB2	SNTA1	0.013	0.154	bioplex_WMM WMM_only
SNTB1	SNTB2	0.012	0.147	bioplex_WMM gupta_WMM WMM_only
DTNA	DTNB	0.012	0.15	bioplex_WMM WMM_only
DTNA	SNTB2	0.011	0.141	bioplex_WMM youn_WMM gupta_WMM WMM_only
DTNA	SNTA1	0.011	0.142	bioplex_WMM WMM_only
SNTB1	DTNA	0.01	0.118	bioplex_WMM WMM_only
SNTB1	CTNNAL1	0.009	0.106	bioplex_WMM WMM_only
CTNNAL1	SNTA1	0.009	0.107	bioplex_WMM WMM_only
CTNNAL1	DTNB	0.009	0.093	bioplex_WMM gupta_WMM WMM_only
DTNB	SNTA1	0.009	0.096	bioplex_WMM WMM_only
SNTB1	DTNB	0.009	0.097	bioplex_WMM WMM_only
CTNNAL1	SNTB2	0.008	0.095	bioplex_WMM youn_WMM gupta_WMM WMM_only
CTNNAL1	DTNA	0.008	0.096	bioplex_WMM youn_WMM gupta_WMM WMM_only

Click to enlarge

Complex HuMAP2_06572 has an average edge precision of 0.368 which is ranked 3660 out of all 6965 complexes.

Genename	Complexes
SNTB2	HuMAP2_00771 HuMAP2_05558 HuMAP2_06572
DTNA	HuMAP2_00771 HuMAP2_06572
SNTA1	HuMAP2_00771 HuMAP2_06572
SNTB1	HuMAP2_00439 HuMAP2_00771 HuMAP2_06572
DTNB	HuMAP2_00771 HuMAP2_05097 HuMAP2_06572
SNTG2	HuMAP2_00771 HuMAP2_05930 HuMAP2_06572
DMD	HuMAP2_00439 HuMAP2_00771 HuMAP2_06572
CTNNAL1	HuMAP2_00439 HuMAP2_00771 HuMAP2_03044 HuMAP2_05845 HuMAP2_06572