hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06612
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CMPK1 | UMP-CMP kinase (EC 2.7.4.14) (Deoxycytidylate kinase) (CK) (dCMP kinase) (Nucleoside-diphosphate kinase) (EC 2.7.4.6) (Uridine monophosphate/cytidine monophosphate kinase) (UMP/CMP kinase) (UMP/CMPK) | UniProt NCBI |
| PGK1 | Phosphoglycerate kinase 1 (EC 2.7.2.3) (Cell migration-inducing gene 10 protein) (Primer recognition protein 2) (PRP 2) | UniProt NCBI |
| GART | Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (Glycinamide ribonucleotide synthetase) (GARS) (Phosphoribosylglycinamide synthetase); Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) (AIR synthase) (AIRS) (Phosphoribosyl-aminoimidazole synthetase); Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) (5'-phosphoribosylglycinamide transformylase) (GAR transformylase) (GART)] | UniProt NCBI |
| PLPBP | Pyridoxal phosphate homeostasis protein (PLP homeostasis protein) (Proline synthase co-transcribed bacterial homolog protein) (Pyridoxal phosphate-binding protein) | UniProt NCBI |
| TPPP3 | Tubulin polymerization-promoting protein family member 3 (TPPP/p20) | UniProt NCBI |
| CKMT2 | Creatine kinase S-type, mitochondrial (EC 2.7.3.2) (Basic-type mitochondrial creatine kinase) (Mib-CK) (Sarcomeric mitochondrial creatine kinase) (S-MtCK) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4290 | 0.00477752328717 | 0.333333333333 | PGK1 GART | Metabolic reprogramming in colon cancer |
| KEGG:01100 | 0.0331288091988 | 0.666666666667 | PGK1 CMPK1 CKMT2 GART | Metabolic pathways |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CMPK1 | CKMT2 | 0.994 | 0.921 | fraction |
| GART | CMPK1 | 0.922 | 0.843 | bioplex_WMM gupta_WMM fraction |
| TPPP3 | CMPK1 | 0.858 | 0.796 | fraction |
| PLPBP | PGK1 | 0.587 | 0.662 | bioplex_WMM Guru fraction |
| PLPBP | CMPK1 | 0.573 | 0.655 | bioplex_WMM youn_WMM fraction |
| PGK1 | CKMT2 | 0.544 | 0.643 | Guru fraction |
| TPPP3 | PLPBP | 0.004 | 0.007 | fraction |
| PGK1 | CMPK1 | 0.0 | 0.007 | bioplex (CMPK1) bioplex_WMM fraction treiber_WMM |
| GART | PGK1 | 0.0 | 0.003 | bioplex_WMM boldt fraction boldt_WMM treiber_WMM |
| TPPP3 | PGK1 | 0.0 | 0.003 | fraction |
| GART | PLPBP | 0.0 | 0.0 | bioplex_WMM gupta_WMM fraction |
Images
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Complex HuMAP2_06612 has an average edge precision of 0.413 which is ranked 3171 out of all 6965 complexes.
Related Complexes