hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06622
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| HMMR | Hyaluronan mediated motility receptor (Intracellular hyaluronic acid-binding protein) (Receptor for hyaluronan-mediated motility) (CD antigen CD168) | UniProt NCBI |
| NFE2L3 | Nuclear factor erythroid 2-related factor 3 (NF-E2-related factor 3) (NFE2-related factor 3) (Nuclear factor, erythroid derived 2, like 3) | UniProt NCBI |
| FAM83D | Protein FAM83D (Spindle protein CHICA) | UniProt NCBI |
| FBXO22 | F-box only protein 22 (F-box protein FBX22p44) | UniProt NCBI |
| MAFB | Transcription factor MafB (Maf-B) (V-maf musculoaponeurotic fibrosarcoma oncogene homolog B) | UniProt NCBI |
| MAFG | Transcription factor MafG (V-maf musculoaponeurotic fibrosarcoma oncogene homolog G) (hMAF) | UniProt NCBI |
| BACH1 | Transcription regulator protein BACH1 (BTB and CNC homolog 1) (HA2303) | UniProt NCBI |
| MAFK | Transcription factor MafK (Erythroid transcription factor NF-E2 p18 subunit) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4269 | 0.000573702400868 | 0.25 | MAFG MAFK | Ethanol metabolism resulting in production of ROS by CYP2E1 |
| CORUM:6359 | 0.0497224828424 | 0.125 | HMMR | RHAMM-beta-catenin complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| HMMR | FAM83D | 0.989 | 0.904 | hein_WMM bioplex (HMMR) bioplex_WMM hein (FAM83D) gupta_WMM boldt_WMM |
| BACH1 | MAFG | 0.984 | 0.899 | hein_WMM bioplex (BACH1) bioplex_WMM hein (BACH1) |
| MAFK | BACH1 | 0.982 | 0.897 | hein_WMM bioplex (BACH1) bioplex_WMM hein (BACH1) |
| BACH1 | HMMR | 0.959 | 0.865 | hein_WMM bioplex (BACH1) bioplex_WMM boldt hein (BACH1) boldt_WMM |
| MAFK | NFE2L3 | 0.877 | 0.811 | bioplex (NFE2L3) bioplex_WMM |
| BACH1 | MAFB | 0.777 | 0.752 | bioplex (BACH1) bioplex_WMM |
| MAFG | NFE2L3 | 0.376 | 0.547 | bioplex (NFE2L3) bioplex_WMM |
| BACH1 | FAM83D | 0.219 | 0.466 | hein_WMM bioplex (BACH1) bioplex_WMM hein (BACH1) boldt_WMM |
| BACH1 | FBXO22 | 0.029 | 0.232 | bioplex (BACH1) bioplex_WMM |
| MAFK | MAFG | 0.012 | 0.144 | hein_WMM bioplex_WMM WMM_only |
| MAFK | MAFB | 0.008 | 0.091 | bioplex_WMM WMM_only |
| MAFK | HMMR | 0.008 | 0.09 | hein_WMM bioplex_WMM WMM_only |
| MAFK | FAM83D | 0.008 | 0.088 | hein_WMM bioplex_WMM WMM_only |
| MAFG | MAFB | 0.008 | 0.087 | bioplex_WMM WMM_only |
| BACH1 | NFE2L3 | 0.008 | 0.085 | bioplex_WMM WMM_only |
| MAFG | HMMR | 0.008 | 0.085 | hein_WMM bioplex_WMM WMM_only |
| MAFG | FAM83D | 0.008 | 0.082 | hein_WMM bioplex_WMM WMM_only |
| MAFB | HMMR | 0.008 | 0.041 | bioplex_WMM WMM_only |
| MAFB | FAM83D | 0.008 | 0.042 | bioplex_WMM WMM_only |
| MAFB | FBXO22 | 0.008 | 0.01 | bioplex_WMM WMM_only |
| MAFK | FBXO22 | 0.007 | 0.008 | bioplex_WMM WMM_only |
| NFE2L3 | FBXO22 | 0.007 | 0.008 | bioplex_WMM WMM_only |
| MAFG | FBXO22 | 0.007 | 0.007 | bioplex_WMM WMM_only |
| HMMR | FBXO22 | 0.007 | 0.004 | bioplex_WMM WMM_only |
| FAM83D | FBXO22 | 0.007 | 0.002 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_06622 has an average edge precision of 0.29 which is ranked 4752 out of all 6965 complexes.
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