hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06631
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SLC25A13 | Calcium-binding mitochondrial carrier protein Aralar2 (Citrin) (Mitochondrial aspartate glutamate carrier 2) (Solute carrier family 25 member 13) | UniProt NCBI |
| SLC25A12 | Calcium-binding mitochondrial carrier protein Aralar1 (Mitochondrial aspartate glutamate carrier 1) (Solute carrier family 25 member 12) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-8963693 | 9.21757904306e-05 | 1.0 | SLC25A13 SLC25A12 | Aspartate and asparagine metabolism |
| REAC:R-HSA-70263 | 0.000729026706133 | 1.0 | SLC25A13 SLC25A12 | Gluconeogenesis |
| GO:0043490 | 0.00270494046827 | 1.0 | SLC25A13 SLC25A12 | malate-aspartate shuttle |
| REAC:R-HSA-1268020 | 0.0029663845284 | 1.0 | SLC25A13 SLC25A12 | Mitochondrial protein import |
| GO:0015183 | 0.00450823411379 | 1.0 | SLC25A13 SLC25A12 | L-aspartate transmembrane transporter activity |
| REAC:R-HSA-70326 | 0.00556574181855 | 1.0 | SLC25A13 SLC25A12 | Glucose metabolism |
| GO:0015810 | 0.00676235117068 | 1.0 | SLC25A13 SLC25A12 | aspartate transmembrane transport |
| REAC:R-HSA-9609507 | 0.0177396498492 | 1.0 | SLC25A13 SLC25A12 | Protein localization |
| GO:0005313 | 0.020287053512 | 1.0 | SLC25A13 SLC25A12 | L-glutamate transmembrane transporter activity |
| GO:0015740 | 0.020287053512 | 1.0 | SLC25A13 SLC25A12 | C4-dicarboxylate transport |
| GO:0015556 | 0.020287053512 | 1.0 | SLC25A13 SLC25A12 | C4-dicarboxylate transmembrane transporter activity |
| GO:0015172 | 0.020287053512 | 1.0 | SLC25A13 SLC25A12 | acidic amino acid transmembrane transporter activity |
| GO:0015813 | 0.029754345151 | 1.0 | SLC25A13 SLC25A12 | L-glutamate transmembrane transport |
| HP:0045082 | 0.0497341708567 | 0.5 | SLC25A13 | Decreased body mass index |
| HP:0011966 | 0.0497341708567 | 0.5 | SLC25A13 | Elevated plasma citrulline |
| HP:0012164 | 0.0497341708567 | 0.5 | SLC25A13 | Asterixis |
| HP:0025235 | 0.0497341708567 | 0.5 | SLC25A13 | Non-rapid eye movement parasomnia |
| HP:0030765 | 0.0497341708567 | 0.5 | SLC25A13 | Sleep terror |
| WP:WP4571 | 0.0499262710315 | 0.5 | SLC25A13 | Urea cycle and related diseases |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SLC25A12 | SLC25A13 | 0.065 | 0.347 | hein_WMM bioplex (SLC25A13) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
Images
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Complex HuMAP2_06631 has an average edge precision of 0.347 which is ranked 4018 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| SLC25A13 | HuMAP2_06631 |
| SLC25A12 | HuMAP2_06446 HuMAP2_06631 |