hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06670
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| GPRC5A | Retinoic acid-induced protein 3 (G-protein coupled receptor family C group 5 member A) (Phorbol ester induced gene 1) (PEIG-1) (Retinoic acid-induced gene 1 protein) (RAIG-1) | UniProt NCBI |
| FLOT2 | Flotillin-2 (Epidermal surface antigen) (ESA) (Membrane component chromosome 17 surface marker 1) | UniProt NCBI |
| DSG2 | Desmoglein-2 (Cadherin family member 5) (HDGC) | UniProt NCBI |
| TMEM79 | Transmembrane protein 79 (Mattrin) | UniProt NCBI |
| MPZL3 | Myelin protein zero-like protein 3 | UniProt NCBI |
| FLOT1 | Flotillin-1 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-8849932 | 0.00419905151199 | 0.333333333333 | FLOT2 FLOT1 | Synaptic adhesion-like molecules |
| GO:0044291 | 0.0207293189685 | 0.5 | FLOT1 DSG2 FLOT2 | cell-cell contact zone |
| WP:WP3915 | 0.0416969783243 | 0.333333333333 | FLOT2 FLOT1 | Angiopoietin Like Protein 8 Regulatory Pathway |
| KEGG:04910 | 0.0474671394747 | 0.333333333333 | FLOT2 FLOT1 | Insulin signaling pathway |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| FLOT2 | FLOT1 | 0.99 | 0.909 | hein_WMM bioplex_WMM youn_WMM hein (FLOT1,FLOT2) |
| FLOT2 | TMEM79 | 0.978 | 0.894 | bioplex (FLOT2) bioplex_WMM |
| MPZL3 | FLOT2 | 0.887 | 0.818 | bioplex (FLOT2) bioplex_WMM |
| MPZL3 | TMEM79 | 0.169 | 0.426 | bioplex (TMEM79) bioplex_WMM |
| DSG2 | FLOT2 | 0.078 | 0.353 | hein_WMM bioplex (FLOT2) bioplex_WMM youn_WMM hein (FLOT2) gupta_WMM |
| FLOT2 | GPRC5A | 0.049 | 0.293 | hein_WMM hein (FLOT2) gupta_WMM |
| DSG2 | FLOT1 | 0.023 | 0.209 | hein_WMM bioplex_WMM youn_WMM hein (FLOT1) |
| FLOT1 | GPRC5A | 0.014 | 0.137 | hein_WMM hein (FLOT1) |
| DSG2 | TMEM79 | 0.007 | 0.001 | bioplex_WMM WMM_only |
| MPZL3 | DSG2 | 0.007 | 0.001 | bioplex_WMM WMM_only |
| DSG2 | GPRC5A | 0.005 | 0.013 | hein_WMM gupta_WMM WMM_only |
Images
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Complex HuMAP2_06670 has an average edge precision of 0.369 which is ranked 3658 out of all 6965 complexes.
Related Complexes