hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06674
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| H2BC1 | Histone H2B type 1-A (Histone H2B, testis) (TSH2B.1) (hTSH2B) (Testis-specific histone H2B) | UniProt NCBI |
| H2BC13 | Histone H2B type 1-L (Histone H2B.c) (H2B/c) | UniProt NCBI |
| MIER1 | Mesoderm induction early response protein 1 (Early response 1) (Er1) (Mi-er1) (hMi-er1) | UniProt NCBI |
| BAHD1 | Bromo adjacent homology domain-containing 1 protein (BAH domain-containing protein 1) | UniProt NCBI |
| C16orf87 | UPF0547 protein C16orf87 | UniProt NCBI |
| MIER3 | Mesoderm induction early response protein 3 (Mi-er3) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-171306 | 0.0280217040903 | 0.333333333333 | H2BC1 H2BC13 | Packaging Of Telomere Ends |
| REAC:R-HSA-110331 | 0.0314333263146 | 0.333333333333 | H2BC1 H2BC13 | Cleavage of the damaged purine |
| REAC:R-HSA-73927 | 0.0314333263146 | 0.333333333333 | H2BC1 H2BC13 | Depurination |
| REAC:R-HSA-110330 | 0.0314333263146 | 0.333333333333 | H2BC1 H2BC13 | Recognition and association of DNA glycosylase with site containing an affected purine |
| REAC:R-HSA-8866654 | 0.0338154872995 | 0.333333333333 | H2BC1 H2BC13 | E3 ubiquitin ligases ubiquitinate target proteins |
| REAC:R-HSA-110329 | 0.036283735834 | 0.333333333333 | H2BC1 H2BC13 | Cleavage of the damaged pyrimidine |
| REAC:R-HSA-73928 | 0.036283735834 | 0.333333333333 | H2BC1 H2BC13 | Depyrimidination |
| REAC:R-HSA-110328 | 0.036283735834 | 0.333333333333 | H2BC1 H2BC13 | Recognition and association of DNA glycosylase with site containing an affected pyrimidine |
| REAC:R-HSA-73929 | 0.0375501136505 | 0.333333333333 | H2BC1 H2BC13 | Base-Excision Repair, AP Site Formation |
| KEGG:05322 | 0.0388413362769 | 0.333333333333 | H2BC1 H2BC13 | Systemic lupus erythematosus |
| REAC:R-HSA-73728 | 0.0414781208299 | 0.333333333333 | H2BC1 H2BC13 | RNA Polymerase I Promoter Opening |
| REAC:R-HSA-5334118 | 0.0442040700727 | 0.333333333333 | H2BC1 H2BC13 | DNA methylation |
| REAC:R-HSA-5625886 | 0.0470157324282 | 0.333333333333 | H2BC1 H2BC13 | Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 |
| REAC:R-HSA-427359 | 0.0484536768126 | 0.333333333333 | H2BC1 H2BC13 | SIRT1 negatively regulates rRNA expression |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| MIER1 | H2BC1 | 0.999 | 0.949 | bioplex (H2BC1) bioplex_WMM |
| H2BC1 | BAHD1 | 0.998 | 0.942 | bioplex (H2BC1) bioplex_WMM |
| H2BC1 | MIER3 | 0.988 | 0.901 | bioplex (H2BC1) bioplex_WMM |
| H2BC1 | H2BC13 | 0.94 | 0.852 | bioplex (H2BC1) bioplex_WMM |
| H2BC1 | C16orf87 | 0.823 | 0.774 | bioplex (H2BC1) bioplex_WMM |
| C16orf87 | MIER3 | 0.777 | 0.752 | bioplex (C16orf87) bioplex_WMM |
| MIER1 | C16orf87 | 0.186 | 0.441 | bioplex (C16orf87) bioplex_WMM |
| MIER1 | MIER3 | 0.014 | 0.138 | hein_WMM bioplex_WMM WMM_only |
| C16orf87 | BAHD1 | 0.011 | 0.145 | bioplex_WMM WMM_only |
| BAHD1 | MIER3 | 0.011 | 0.145 | bioplex_WMM WMM_only |
| MIER1 | BAHD1 | 0.01 | 0.121 | bioplex_WMM WMM_only |
| BAHD1 | H2BC13 | 0.008 | 0.084 | bioplex_WMM WMM_only |
| C16orf87 | H2BC13 | 0.008 | 0.06 | bioplex_WMM WMM_only |
| H2BC13 | MIER3 | 0.008 | 0.06 | bioplex_WMM WMM_only |
| MIER1 | H2BC13 | 0.008 | 0.014 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_06674 has an average edge precision of 0.425 which is ranked 3070 out of all 6965 complexes.
Related Complexes