hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06686
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PER1 | Period circadian protein homolog 1 (hPER1) (Circadian clock protein PERIOD 1) (Circadian pacemaker protein Rigui) | UniProt NCBI |
| CRY2 | Cryptochrome-2 | UniProt NCBI |
| CRY1 | Cryptochrome-1 | UniProt NCBI |
| TEKT4 | Tektin-4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04710 | 9.81974852015e-07 | 0.75 | CRY2 PER1 CRY1 | Circadian rhythm |
| WP:WP3298 | 1.01280445831e-06 | 0.75 | CRY2 PER1 CRY1 | Melatonin metabolism and effects |
| WP:WP410 | 2.58521566797e-06 | 0.75 | CRY2 PER1 CRY1 | Exercise-induced Circadian Regulation |
| GO:2000323 | 7.26438828159e-06 | 0.75 | CRY2 PER1 CRY1 | negative regulation of glucocorticoid receptor signaling pathway |
| GO:2000322 | 7.26438828159e-06 | 0.75 | CRY2 PER1 CRY1 | regulation of glucocorticoid receptor signaling pathway |
| GO:0031958 | 4.35775472874e-05 | 0.75 | CRY2 PER1 CRY1 | corticosteroid receptor signaling pathway |
| GO:0042921 | 4.35775472874e-05 | 0.75 | CRY2 PER1 CRY1 | glucocorticoid receptor signaling pathway |
| REAC:R-HSA-400253 | 5.88039824914e-05 | 0.75 | CRY2 PER1 CRY1 | Circadian Clock |
| WP:WP3594 | 0.000155677737629 | 0.75 | CRY2 PER1 CRY1 | Circadian rhythm related genes |
| GO:0043153 | 0.000296207880886 | 0.75 | CRY2 PER1 CRY1 | entrainment of circadian clock by photoperiod |
| GO:0009648 | 0.000351729129078 | 0.75 | CRY2 PER1 CRY1 | photoperiodism |
| GO:0009649 | 0.000482716802139 | 0.75 | CRY2 PER1 CRY1 | entrainment of circadian clock |
| GO:0033144 | 0.00106129291317 | 0.75 | CRY2 PER1 CRY1 | negative regulation of intracellular steroid hormone receptor signaling pathway |
| GO:0009882 | 0.00270494046827 | 0.5 | CRY2 CRY1 | blue light photoreceptor activity |
| GO:0009785 | 0.00270494046827 | 0.5 | CRY2 CRY1 | blue light signaling pathway |
| GO:0009637 | 0.00270494046827 | 0.5 | CRY2 CRY1 | response to blue light |
| GO:0071483 | 0.00270494046827 | 0.5 | CRY2 CRY1 | cellular response to blue light |
| GO:0032922 | 0.0100430829723 | 0.75 | CRY2 PER1 CRY1 | circadian regulation of gene expression |
| GO:0033143 | 0.011776375189 | 0.75 | CRY2 PER1 CRY1 | regulation of intracellular steroid hormone receptor signaling pathway |
| GO:0042752 | 0.0297308662285 | 0.75 | CRY2 PER1 CRY1 | regulation of circadian rhythm |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CRY1 | PER1 | 0.998 | 0.944 | hein_WMM bioplex (CRY1,PER1) bioplex_WMM hein (CRY1) |
| CRY2 | CRY1 | 0.996 | 0.929 | hein_WMM bioplex (CRY1) bioplex_WMM |
| CRY2 | TEKT4 | 0.076 | 0.357 | bioplex (TEKT4) bioplex_WMM |
| CRY1 | TEKT4 | 0.074 | 0.356 | bioplex (TEKT4) bioplex_WMM |
| CRY2 | PER1 | 0.011 | 0.148 | hein_WMM bioplex_WMM WMM_only |
Images
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Complex HuMAP2_06686 has an average edge precision of 0.547 which is ranked 2218 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PER1 | HuMAP2_02639 HuMAP2_02822 HuMAP2_03989 HuMAP2_05794 HuMAP2_06686 |
| CRY2 | HuMAP2_02639 HuMAP2_02822 HuMAP2_06178 HuMAP2_06686 |
| CRY1 | HuMAP2_02639 HuMAP2_02822 HuMAP2_05794 HuMAP2_06178 HuMAP2_06686 |
| TEKT4 | HuMAP2_02639 HuMAP2_06049 HuMAP2_06178 HuMAP2_06217 HuMAP2_06686 |