hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_06696
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ULBP3 | UL16-binding protein 3 (ALCAN-gamma) (NKG2D ligand 3) (N2DL-3) (NKG2DL3) (Retinoic acid early transcript 1N) | UniProt NCBI |
| ULBP1 | UL16-binding protein 1 (ALCAN-beta) (NKG2D ligand 1) (N2DL-1) (NKG2DL1) (Retinoic acid early transcript 1I) | UniProt NCBI |
| SLC39A5 | Zinc transporter ZIP5 (Solute carrier family 39 member 5) (Zrt- and Irt-like protein 5) (ZIP-5) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04650 | 0.00216302764905 | 0.666666666667 | ULBP3 ULBP1 | Natural killer cell mediated cytotoxicity |
| GO:0046703 | 0.0135228859698 | 0.666666666667 | ULBP3 ULBP1 | natural killer cell lectin-like receptor binding |
| REAC:R-HSA-198933 | 0.0216163677069 | 0.666666666667 | ULBP3 ULBP1 | Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| CORUM:1773 | 0.0249904952816 | 0.333333333333 | ULBP3 | ULBP3-KLRK1-HCST complex |
| CORUM:3213 | 0.0249904952816 | 0.333333333333 | ULBP1 | ULBP1-KLRK1-HCST complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ULBP1 | ULBP3 | 0.535 | 0.64 | bioplex (ULBP1) bioplex_WMM |
| ULBP1 | SLC39A5 | 0.098 | 0.357 | bioplex (SLC39A5) bioplex_WMM |
| ULBP3 | SLC39A5 | 0.017 | 0.174 | bioplex (SLC39A5) bioplex_WMM |
Images
Click to enlarge
Complex HuMAP2_06696 has an average edge precision of 0.39 which is ranked 3422 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ULBP3 | HuMAP2_03740 HuMAP2_06696 |
| ULBP1 | HuMAP2_03740 HuMAP2_06696 |
| SLC39A5 | HuMAP2_03925 HuMAP2_06696 |