hu.MAP 2.0: Complex View

Human Protein Complex Map

Genename	Protein Name	Links
EGLN1	Egl nine homolog 1 (EC 1.14.11.29) (Hypoxia-inducible factor prolyl hydroxylase 2) (HIF-PH2) (HIF-prolyl hydroxylase 2) (HPH-2) (Prolyl hydroxylase domain-containing protein 2) (PHD2) (SM-20)	UniProt NCBI
GIPC1	PDZ domain-containing protein GIPC1 (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (RGS19-interacting protein 1) (Synectin) (Tax interaction protein 2) (TIP-2)	UniProt NCBI
DHX15	Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 (EC 3.6.4.13) (ATP-dependent RNA helicase #46) (DEAH box protein 15)	UniProt NCBI
SERPINE1	Plasminogen activator inhibitor 1 (PAI) (PAI-1) (Endothelial plasminogen activator inhibitor) (Serpin E1)	UniProt NCBI
EML2	Echinoderm microtubule-associated protein-like 2 (EMAP-2) (HuEMAP-2)	UniProt NCBI
APIP	Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) (APAF1-interacting protein) (hAPIP)	UniProt NCBI
UTP14A	U3 small nucleolar RNA-associated protein 14 homolog A (Antigen NY-CO-16) (Serologically defined colon cancer antigen 16)	UniProt NCBI
HMGB2	High mobility group protein B2 (High mobility group protein 2) (HMG-2)	UniProt NCBI
ERH	Enhancer of rudimentary homolog	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
WP:WP3614	0.0101633326185	0.222222222222	SERPINE1 EGLN1	Photodynamic therapy-induced HIF-1 survival signaling
HPA:032020_22	0.0469668390052	0.666666666667	GIPC1 EGLN1 EML2 DHX15 ERH APIP	pancreas; islets of Langerhans[Approved,Medium]
CORUM:2486	0.0499262710315	0.111111111111	GIPC1	GIPC1-LHCGR complex

Protein 1	Protein 2	Score	Precision	Evidence
DHX15	EML2	0.135	0.406	fraction
UTP14A	DHX15	0.064	0.348	bioplex_WMM gupta_WMM fraction treiber_WMM
DHX15	HMGB2	0.042	0.27	bioplex_WMM gupta_WMM fraction
DHX15	ERH	0.026	0.22	bioplex_WMM gupta_WMM fraction
GIPC1	DHX15	0.023	0.208	bioplex_WMM gupta_WMM fraction
DHX15	SERPINE1	0.023	0.211	fraction
DHX15	EGLN1	0.022	0.211	bioplex_WMM gupta_WMM fraction
GIPC1	APIP	0.02	0.188	bioplex (APIP) fraction
GIPC1	ERH	0.007	0.006	bioplex_WMM gupta_WMM WMM_only
GIPC1	EGLN1	0.007	0.005	bioplex_WMM youn_WMM gupta_WMM WMM_only
GIPC1	UTP14A	0.007	0.003	bioplex_WMM WMM_only
HMGB2	ERH	0.007	0.006	bioplex_WMM gupta_WMM WMM_only
ERH	EGLN1	0.007	0.002	bioplex_WMM youn_WMM gupta_WMM WMM_only
UTP14A	EGLN1	0.007	0.005	bioplex_WMM youn_WMM gupta_WMM WMM_only
GIPC1	HMGB2	0.007	0.0	bioplex_WMM WMM_only
EML2	ERH	0.007	0.006	bioplex_WMM WMM_only
UTP14A	HMGB2	0.007	0.003	bioplex_WMM gupta_WMM WMM_only
HMGB2	APIP	0.007	0.009	hein_WMM WMM_only
HMGB2	EGLN1	0.007	0.004	bioplex_WMM gupta_WMM WMM_only
APIP	ERH	0.007	0.002	bioplex (APIP)
UTP14A	ERH	0.0	0.018	bioplex_WMM youn_WMM gupta_WMM fraction
GIPC1	EML2	0.0	0.011	fraction

Click to enlarge

Complex HuMAP2_06704 has an average edge precision of 0.097 which is ranked 6939 out of all 6965 complexes.

Genename	Complexes
EGLN1	HuMAP2_03627 HuMAP2_06704
GIPC1	HuMAP2_00349 HuMAP2_00995 HuMAP2_01966 HuMAP2_06704
DHX15	HuMAP2_00420 HuMAP2_00707 HuMAP2_04312 HuMAP2_06071 HuMAP2_06704
SERPINE1	HuMAP2_03975 HuMAP2_06704
EML2	HuMAP2_00420 HuMAP2_00602 HuMAP2_01476 HuMAP2_02303 HuMAP2_02498 HuMAP2_06704
APIP	HuMAP2_00995 HuMAP2_01037 HuMAP2_01966 HuMAP2_02594 HuMAP2_02608 HuMAP2_03446 HuMAP2_04166 HuMAP2_06704
UTP14A	HuMAP2_00420 HuMAP2_02559 HuMAP2_06704
HMGB2	HuMAP2_00876 HuMAP2_03246 HuMAP2_05394 HuMAP2_05836 HuMAP2_06704
ERH	HuMAP2_03008 HuMAP2_03398 HuMAP2_06704