hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06709
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SLC7A1 | High affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (Ecotropic retroviral leukemia receptor homolog) (Ecotropic retrovirus receptor homolog) (Solute carrier family 7 member 1) (System Y+ basic amino acid transporter) | UniProt NCBI |
| SIGMAR1 | Sigma non-opioid intracellular receptor 1 (Aging-associated gene 8 protein) (SR31747-binding protein) (SR-BP) (Sigma 1-type opioid receptor) (SIG-1R) (Sigma1-receptor) (Sigma1R) (hSigmaR1) | UniProt NCBI |
| SLC33A1 | Acetyl-coenzyme A transporter 1 (AT-1) (Acetyl-CoA transporter 1) (Solute carrier family 33 member 1) | UniProt NCBI |
| AGPAT4 | 1-acyl-sn-glycerol-3-phosphate acyltransferase delta (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 4) (1-AGP acyltransferase 4) (1-AGPAT 4) (Lysophosphatidic acid acyltransferase delta) (LPAAT-delta) | UniProt NCBI |
| SCAMP2 | Secretory carrier-associated membrane protein 2 (Secretory carrier membrane protein 2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| MIRNA:hsa-miR-6850-3p | 0.0103546923852 | 0.4 | AGPAT4 SLC33A1 | hsa-miR-6850-3p |
| CORUM:1695 | 0.0499494897235 | 0.2 | SCAMP2 | SCAMP1-SCAMP2 complex |
| CORUM:6735 | 0.0499494897235 | 0.2 | SIGMAR1 | SIGMAR1-KCNH2 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SLC7A1 | SLC33A1 | 0.585 | 0.663 | hein_WMM bioplex (SLC7A1) bioplex_WMM hein (SLC33A1) gupta_WMM |
| AGPAT4 | SLC7A1 | 0.081 | 0.349 | bioplex (SLC7A1) bioplex_WMM boldt boldt_WMM |
| SCAMP2 | SLC7A1 | 0.055 | 0.31 | bioplex (SLC7A1) bioplex_WMM boldt gupta_WMM boldt_WMM |
| SLC7A1 | SIGMAR1 | 0.044 | 0.274 | bioplex (SLC7A1) bioplex_WMM boldt gupta_WMM boldt_WMM |
| AGPAT4 | SIGMAR1 | 0.008 | 0.066 | bioplex_WMM boldt boldt_WMM |
| SCAMP2 | SIGMAR1 | 0.006 | 0.003 | bioplex_WMM boldt gupta_WMM boldt_WMM |
| SCAMP2 | AGPAT4 | 0.006 | 0.005 | bioplex_WMM boldt boldt_WMM |
| AGPAT4 | SLC33A1 | 0.003 | 0.014 | bioplex_WMM WMM_only |
| SCAMP2 | SLC33A1 | 0.003 | 0.014 | bioplex_WMM gupta_WMM WMM_only |
| SIGMAR1 | SLC33A1 | 0.003 | 0.016 | bioplex_WMM gupta_WMM WMM_only |
Images
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Complex HuMAP2_06709 has an average edge precision of 0.171 which is ranked 6512 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| SLC7A1 | HuMAP2_02958 HuMAP2_03820 HuMAP2_06709 |
| SIGMAR1 | HuMAP2_02958 HuMAP2_05696 HuMAP2_06709 |
| SLC33A1 | HuMAP2_03820 HuMAP2_06537 HuMAP2_06709 |
| AGPAT4 | HuMAP2_02958 HuMAP2_06709 |
| SCAMP2 | HuMAP2_00889 HuMAP2_06709 |