hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06712
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| MORF4L1 | Mortality factor 4-like protein 1 (MORF-related gene 15 protein) (Protein MSL3-1) (Transcription factor-like protein MRG15) | UniProt NCBI |
| MRFAP1 | MORF4 family-associated protein 1 (Protein PGR1) (Protein associated with MRG of 14 kDa) | UniProt NCBI |
| MORF4L2 | Mortality factor 4-like protein 2 (MORF-related gene X protein) (Protein MSL3-2) (Transcription factor-like protein MRGX) | UniProt NCBI |
| MRGBP | MRG/MORF4L-binding protein (MRG-binding protein) (Up-regulated in colon cancer 4) (Urcc4) | UniProt NCBI |
| PALB2 | Partner and localizer of BRCA2 | UniProt NCBI |
| MRFAP1L1 | MORF4 family-associated protein 1-like 1 | UniProt NCBI |
| EP400P1 | NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:528 | 1.02351294033e-06 | 0.5 | MORF4L2 MRGBP MORF4L1 | NuA4/Tip60-HAT complex |
| CORUM:529 | 1.25951779514e-06 | 0.5 | MORF4L2 MRGBP MORF4L1 | NuA4/Tip60-HAT complex |
| CORUM:722 | 2.51655344529e-05 | 0.333333333333 | MRFAP1 MORF4L1 | MRG15-PAM14-RB complex |
| CORUM:723 | 2.51655344529e-05 | 0.333333333333 | MRFAP1 MORF4L1 | MRG15-PAM14-RB complex |
| CORUM:798 | 0.000878902571644 | 0.333333333333 | MRGBP MORF4L1 | NuA4/Tip60-HAT complex A |
| GO:0035267 | 0.00175581235783 | 0.5 | MORF4L2 MRGBP MORF4L1 | NuA4 histone acetyltransferase complex |
| GO:0043189 | 0.00175581235783 | 0.5 | MORF4L2 MRGBP MORF4L1 | H4/H2A histone acetyltransferase complex |
| REAC:R-HSA-3214847 | 0.00272420329871 | 0.5 | MORF4L2 MRGBP MORF4L1 | HATs acetylate histones |
| REAC:R-HSA-3247509 | 0.0183482160149 | 0.5 | MORF4L2 MRGBP MORF4L1 | Chromatin modifying enzymes |
| REAC:R-HSA-4839726 | 0.0183482160149 | 0.5 | MORF4L2 MRGBP MORF4L1 | Chromatin organization |
| GO:1902562 | 0.0192515670318 | 0.5 | MORF4L2 MRGBP MORF4L1 | H4 histone acetyltransferase complex |
| CORUM:724 | 0.0499726005494 | 0.166666666667 | MORF4L1 | MAF2 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| MORF4L1 | EP400P1 | 1.0 | 0.949 | bioplex (MORF4L1) bioplex_WMM |
| MORF4L1 | MRFAP1L1 | 1.0 | 0.949 | bioplex (MORF4L1) bioplex_WMM |
| MORF4L1 | MRGBP | 0.997 | 0.934 | hein_WMM bioplex (MORF4L1,MRGBP) bioplex_WMM Guru fraction |
| MORF4L1 | MORF4L2 | 0.994 | 0.92 | hein_WMM bioplex (MORF4L1,MORF4L2) bioplex_WMM |
| MRFAP1L1 | MORF4L2 | 0.945 | 0.856 | bioplex (MORF4L2) bioplex_WMM |
| MRFAP1 | MORF4L1 | 0.941 | 0.854 | bioplex (MORF4L1) bioplex_WMM |
| PALB2 | MORF4L1 | 0.925 | 0.843 | bioplex (MORF4L1) bioplex_WMM |
| MRGBP | EP400P1 | 0.875 | 0.809 | bioplex (MRGBP) bioplex_WMM |
| EP400P1 | MORF4L2 | 0.742 | 0.739 | bioplex (MORF4L2) bioplex_WMM |
| PALB2 | MORF4L2 | 0.261 | 0.482 | bioplex (MORF4L2) bioplex_WMM |
| MRFAP1 | MORF4L2 | 0.133 | 0.406 | bioplex (MORF4L2) bioplex_WMM |
| MRGBP | MORF4L2 | 0.051 | 0.296 | hein_WMM bioplex (MORF4L2,MRGBP) bioplex_WMM Guru fraction |
| PALB2 | MRFAP1L1 | 0.012 | 0.149 | bioplex_WMM WMM_only |
| MRFAP1 | MRFAP1L1 | 0.011 | 0.14 | bioplex_WMM WMM_only |
| MRFAP1 | PALB2 | 0.011 | 0.14 | bioplex_WMM WMM_only |
| EP400P1 | MRFAP1L1 | 0.011 | 0.137 | bioplex_WMM WMM_only |
| PALB2 | EP400P1 | 0.011 | 0.137 | bioplex_WMM WMM_only |
| MRFAP1 | EP400P1 | 0.011 | 0.143 | bioplex_WMM WMM_only |
| PALB2 | MRGBP | 0.009 | 0.106 | bioplex_WMM WMM_only |
| MRGBP | MRFAP1L1 | 0.009 | 0.106 | bioplex_WMM WMM_only |
| MRFAP1 | MRGBP | 0.009 | 0.1 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_06712 has an average edge precision of 0.485 which is ranked 2590 out of all 6965 complexes.
Related Complexes