hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06714
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| HSPA1B | Heat shock 70 kDa protein 1B (Heat shock 70 kDa protein 2) (HSP70-2) (HSP70.2) | UniProt NCBI |
| LDB3 | LIM domain-binding protein 3 (Protein cypher) (Z-band alternatively spliced PDZ-motif protein) | UniProt NCBI |
| ASAP3 | Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 (Development and differentiation-enhancing factor-like 1) (Protein up-regulated in liver cancer 1) | UniProt NCBI |
| ASAP1 | Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 (130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein) (ADP-ribosylation factor-directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (DEF-1) (Differentiation-enhancing factor 1) (PIP2-dependent ARF1 GAP) | UniProt NCBI |
| CER1 | Cerberus (Cerberus-related protein) (DAN domain family member 4) | UniProt NCBI |
| KLHL15 | Kelch-like protein 15 | UniProt NCBI |
| CD96 | T-cell surface protein tactile (Cell surface antigen CD96) (T cell-activated increased late expression protein) (CD antigen CD96) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04144 | 0.00645172813212 | 0.428571428571 | ASAP1 ASAP3 HSPA1B | Endocytosis |
| KEGG:04666 | 0.0372632222286 | 0.285714285714 | ASAP1 ASAP3 | Fc gamma R-mediated phagocytosis |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CD96 | HSPA1B | 0.984 | 0.899 | bioplex (CD96) bioplex_WMM |
| LDB3 | HSPA1B | 0.896 | 0.821 | bioplex (LDB3) bioplex_WMM |
| CER1 | HSPA1B | 0.433 | 0.578 | bioplex (CER1) bioplex_WMM |
| ASAP3 | HSPA1B | 0.379 | 0.549 | bioplex (ASAP3) bioplex_WMM boldt_WMM |
| ASAP1 | ASAP3 | 0.124 | 0.396 | bioplex (ASAP3) bioplex_WMM |
| CER1 | KLHL15 | 0.023 | 0.209 | bioplex (CER1) bioplex_WMM |
| ASAP1 | HSPA1B | 0.008 | 0.045 | bioplex_WMM WMM_only boldt_WMM |
| ASAP1 | KLHL15 | 0.007 | 0.001 | bioplex_WMM youn_WMM WMM_only |
| HSPA1B | KLHL15 | 0.007 | 0.003 | bioplex_WMM WMM_only |
| ASAP3 | KLHL15 | 0.004 | 0.009 | bioplex (ASAP3) bioplex_WMM |
Images
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Complex HuMAP2_06714 has an average edge precision of 0.351 which is ranked 3929 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| HSPA1B | HuMAP2_02246 HuMAP2_04057 HuMAP2_06714 |
| LDB3 | HuMAP2_02246 HuMAP2_04057 HuMAP2_06714 |
| ASAP3 | HuMAP2_01102 HuMAP2_02246 HuMAP2_03828 HuMAP2_06714 |
| ASAP1 | HuMAP2_00974 HuMAP2_01102 HuMAP2_03828 HuMAP2_06714 |
| CER1 | HuMAP2_02246 HuMAP2_04673 HuMAP2_06714 |
| KLHL15 | HuMAP2_04673 HuMAP2_06714 |
| CD96 | HuMAP2_02246 HuMAP2_04057 HuMAP2_04188 HuMAP2_06714 |